61 items (Ornithorhynchus anatinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EDN1	Endothelin 1. (204 aa)
	COPA	COPI_C domain-containing protein. (97 aa)
	RFLB	IlGF domain-containing protein. (212 aa)
	K7EE70_ORNAN	Uncharacterized protein. (92 aa)
	K7EDK9_ORNAN	COPI_C domain-containing protein. (90 aa)
	F7EPU8_ORNAN	Uncharacterized protein. (249 aa)
	LOC103165823	Uncharacterized protein. (111 aa)
	STC1	Stanniocalcin 1. (247 aa)
	F6WQV7_ORNAN	Uncharacterized protein. (674 aa)
	F7ECZ0_ORNAN	C1q domain-containing protein. (336 aa)
	GPHB5	Glycoprotein hormone subunit beta 5. (146 aa)
	F6UH39_ORNAN	Uncharacterized protein. (2515 aa)
	INHBA	Inhibin subunit beta A. (429 aa)
	FSHB	Follicle stimulating hormone subunit beta. (129 aa)
	PRL	Prolactin. (229 aa)
	CALCA	CALCITONIN domain-containing protein. (143 aa)
	F7E613_ORNAN	Gastrin domain-containing protein. (119 aa)
	NPPC	C-type natriuretic peptide 39; Venom component with vasorelaxant activity. In vitro stimulates the production of cGMP in rat aortic smooth muscle cells and histamine release from rat peritoneal mast cells. Induces relaxation of isolated rat uterus. Induces local edema following subplantar injection into rat hind paw. Forms voltage-dependent cation channels which are weakly selective for potassium relative to sodium, and whose conductance decreases with increasing dehydration energy of the monovalent cation. The activity of the fast cation channels is calcium dependent and is characteri [...] (39 aa)
	FBN1	Fibrillin 1. (2404 aa)
	AVP	Uncharacterized protein; Belongs to the vasopressin/oxytocin family. (164 aa)
	OXT	Uncharacterized protein; Belongs to the vasopressin/oxytocin family. (124 aa)
	NPY	Uncharacterized protein. (97 aa)
	F7F846_ORNAN	TGF_BETA_2 domain-containing protein. (289 aa)
	F6QAC6_ORNAN	Uncharacterized protein. (82 aa)
	PYY	Uncharacterized protein. (70 aa)
	F7EBQ7_ORNAN	WD_REPEATS_REGION domain-containing protein. (234 aa)
	GAL	Uncharacterized protein. (80 aa)
	UTS2	Uncharacterized protein. (124 aa)
	F7G073_ORNAN	CALCITONIN domain-containing protein. (86 aa)
	F6Y8N5_ORNAN	IlGF domain-containing protein. (148 aa)
	MLN	Motilin. (116 aa)
	F6TAA8_ORNAN	TGF_BETA_2 domain-containing protein. (353 aa)
	STC2	Uncharacterized protein. (84 aa)
	ENSOANP00000030659	annotation not available (73 aa)
	GRP	Uncharacterized protein. (98 aa)
	IAPP	Uncharacterized protein. (141 aa)
	K7E6G1_ORNAN	Uncharacterized protein. (82 aa)
	F6X3T4_ORNAN	Uncharacterized protein. (138 aa)
	LEP	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
	SST	Somatostatin. (116 aa)
	QRFP	Uncharacterized protein. (136 aa)
	F7FEI9_ORNAN	Uncharacterized protein. (280 aa)
	PTHLH	Parathyroid hormone like hormone. (177 aa)
	CRH	Corticotropin releasing hormone. (164 aa)
	NPPA	Natriuretic peptide A. (150 aa)
	ANGPTL8	Uncharacterized protein. (199 aa)
	AGRP	Agouti domain-containing protein. (140 aa)
	VIP	Vasoactive intestinal peptide. (200 aa)
	ADIPOQ	Adiponectin, C1Q and collagen domain containing. (249 aa)
	OSTN	Uncharacterized protein. (135 aa)
	TSHB	Thyroid stimulating hormone subunit beta. (136 aa)
	IGF1	Insulin like growth factor 1. (153 aa)
	PMCH	Pro-melanin concentrating hormone. (168 aa)
	TTR	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (149 aa)
	FNDC4	Fibronectin type III domain containing 4. (399 aa)
	METRNL	Meteorin like, glial cell differentiation regulator. (261 aa)
	FNDC5	Fibronectin type III domain containing 5. (225 aa)
	F7CI36_ORNAN	Uncharacterized protein. (159 aa)
	NTS	Neurotensin. (168 aa)
	F6WBC6_ORNAN	Uncharacterized protein. (179 aa)
	CGA	Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (121 aa)

Your Current Organism:

Ornithorhynchus anatinus

NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADIPOQ	AGRP	ENSOANP00000006343	ENSOANP00000005612	Adiponectin, C1Q and collagen domain containing.	Agouti domain-containing protein.	0.412
ADIPOQ	LEP	ENSOANP00000006343	ENSOANP00000001265	Adiponectin, C1Q and collagen domain containing.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	0.867
ADIPOQ	LOC103165823	ENSOANP00000006343	ENSOANP00000012516	Adiponectin, C1Q and collagen domain containing.	Uncharacterized protein.	0.835
AGRP	ADIPOQ	ENSOANP00000005612	ENSOANP00000006343	Agouti domain-containing protein.	Adiponectin, C1Q and collagen domain containing.	0.412
AGRP	CRH	ENSOANP00000005612	ENSOANP00000003650	Agouti domain-containing protein.	Corticotropin releasing hormone.	0.400
AGRP	F6QAC6_ORNAN	ENSOANP00000005612	ENSOANP00000022113	Agouti domain-containing protein.	Uncharacterized protein.	0.574
AGRP	F7E613_ORNAN	ENSOANP00000005612	ENSOANP00000019000	Agouti domain-containing protein.	Gastrin domain-containing protein.	0.679
AGRP	F7EPU8_ORNAN	ENSOANP00000005612	ENSOANP00000011257	Agouti domain-containing protein.	Uncharacterized protein.	0.726
AGRP	GAL	ENSOANP00000005612	ENSOANP00000026788	Agouti domain-containing protein.	Uncharacterized protein.	0.404
AGRP	LEP	ENSOANP00000005612	ENSOANP00000001265	Agouti domain-containing protein.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	0.751
AGRP	NPY	ENSOANP00000005612	ENSOANP00000021119	Agouti domain-containing protein.	Uncharacterized protein.	0.688
AGRP	NTS	ENSOANP00000005612	ENSOANP00000010598	Agouti domain-containing protein.	Neurotensin.	0.501
AGRP	PMCH	ENSOANP00000005612	ENSOANP00000008848	Agouti domain-containing protein.	Pro-melanin concentrating hormone.	0.560
AGRP	PYY	ENSOANP00000005612	ENSOANP00000026546	Agouti domain-containing protein.	Uncharacterized protein.	0.510
AVP	CRH	ENSOANP00000020603	ENSOANP00000003650	Uncharacterized protein; Belongs to the vasopressin/oxytocin family.	Corticotropin releasing hormone.	0.437
AVP	EDN1	ENSOANP00000020603	ENSOANP00000011454	Uncharacterized protein; Belongs to the vasopressin/oxytocin family.	Endothelin 1.	0.406
AVP	F6QAC6_ORNAN	ENSOANP00000020603	ENSOANP00000022113	Uncharacterized protein; Belongs to the vasopressin/oxytocin family.	Uncharacterized protein.	0.589
AVP	F7E613_ORNAN	ENSOANP00000020603	ENSOANP00000019000	Uncharacterized protein; Belongs to the vasopressin/oxytocin family.	Gastrin domain-containing protein.	0.593
AVP	F7EPU8_ORNAN	ENSOANP00000020603	ENSOANP00000011257	Uncharacterized protein; Belongs to the vasopressin/oxytocin family.	Uncharacterized protein.	0.539
AVP	NPPA	ENSOANP00000020603	ENSOANP00000004354	Uncharacterized protein; Belongs to the vasopressin/oxytocin family.	Natriuretic peptide A.	0.414