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F6YRH5_ORNAN F6YRH5_ORNAN COX5B COX5B F6SB95_ORNAN F6SB95_ORNAN NDUFAF1 NDUFAF1 NDUFA8 NDUFA8 NDUFA5 NDUFA5 NDUFV2 NDUFV2 F7BE85_ORNAN F7BE85_ORNAN SDHAF2 SDHAF2 THAP11 THAP11 FDX1 FDX1 F6R4E9_ORNAN F6R4E9_ORNAN COX5A COX5A NDUFA12 NDUFA12 PPARGC1A PPARGC1A F7EGX2_ORNAN F7EGX2_ORNAN ETFA ETFA NDUFB3 NDUFB3 DGUOK DGUOK NDUFS3 NDUFS3 POLG2 POLG2 NDUFB8 NDUFB8 SLC25A12 SLC25A12 F7FX85_ORNAN F7FX85_ORNAN NDUFV1 NDUFV1 COX7A2L COX7A2L LOC100077443 LOC100077443 F7F063_ORNAN F7F063_ORNAN SDHC SDHC COQ9 COQ9 F7GBR6_ORNAN F7GBR6_ORNAN F6RZD5_ORNAN F6RZD5_ORNAN WDR93 WDR93 SDHA SDHA PPP1R32 PPP1R32 BID BID F6YGN7_ORNAN F6YGN7_ORNAN AIFM2 AIFM2 ETFRF1 ETFRF1 TAZ TAZ F6UXN2_ORNAN F6UXN2_ORNAN VSIG10L VSIG10L NDUFS7 NDUFS7 COX4I1 COX4I1 F7FC11_ORNAN F7FC11_ORNAN B3GNTL1 B3GNTL1 SLC25A18 SLC25A18 F6THK4_ORNAN F6THK4_ORNAN NDUFA10 NDUFA10 F6RVT0_ORNAN F6RVT0_ORNAN NDUFS1 NDUFS1 UQCRFS1 UQCRFS1 ETFB ETFB UQCRC1 UQCRC1 NDUFS4 NDUFS4 F7ERV2_ORNAN F7ERV2_ORNAN F7D2R6_ORNAN F7D2R6_ORNAN STEAP4 STEAP4 COX7A2 COX7A2 AFG1L AFG1L CIAPIN1 CIAPIN1 COX2 COX2 COX1 COX1 MT-ND2 MT-ND2 ND1 ND1 NDUFB9 NDUFB9 F6VR07_ORNAN F6VR07_ORNAN F6QXP8_ORNAN F6QXP8_ORNAN F6QXN8_ORNAN F6QXN8_ORNAN F7E0V4_ORNAN F7E0V4_ORNAN F6TB01_ORNAN F6TB01_ORNAN FDX2 FDX2 F6X4C6_ORNAN F6X4C6_ORNAN NDUFB6 NDUFB6 K7E9B4_ORNAN K7E9B4_ORNAN K7E9P9_ORNAN K7E9P9_ORNAN UQCRQ UQCRQ K7EI71_ORNAN K7EI71_ORNAN COX3 COX3 MT-ND3 MT-ND3 ND4L ND4L MT-ND4 MT-ND4 MT-ND5 MT-ND5 ND6 ND6 CYTB CYTB ETFDH ETFDH NQO2 NQO2 F7EPH9_ORNAN F7EPH9_ORNAN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F6YRH5_ORNANProtein kinase domain-containing protein. (453 aa)
COX5BCytochrome c oxidase subunit 5B. (98 aa)
F6SB95_ORNANUncharacterized protein. (56 aa)
NDUFAF1NADH:ubiquinone oxidoreductase complex assembly factor 1. (321 aa)
NDUFA8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (156 aa)
NDUFA5NADH:ubiquinone oxidoreductase subunit A5. (116 aa)
NDUFV2NADH:ubiquinone oxidoreductase core subunit V2. (225 aa)
F7BE85_ORNANUncharacterized protein. (538 aa)
SDHAF2Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (166 aa)
THAP11THAP domain containing 11. (294 aa)
FDX1Ferredoxin 1. (146 aa)
F6R4E9_ORNANUncharacterized protein. (486 aa)
COX5ACytochrome c oxidase subunit 5A. (141 aa)
NDUFA12NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (198 aa)
PPARGC1APPARG coactivator 1 alpha. (795 aa)
F7EGX2_ORNANUncharacterized protein. (95 aa)
ETFAUncharacterized protein. (232 aa)
NDUFB3NADH:ubiquinone oxidoreductase subunit B3. (96 aa)
DGUOKdNK domain-containing protein. (192 aa)
NDUFS3NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (264 aa)
POLG2DNA polymerase gamma 2, accessory subunit. (378 aa)
NDUFB8Uncharacterized protein. (128 aa)
SLC25A12Solute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family. (665 aa)
F7FX85_ORNANUncharacterized protein. (110 aa)
NDUFV1NADH_4Fe-4S domain-containing protein. (73 aa)
COX7A2LCytochrome c oxidase subunit 7A2 like. (131 aa)
LOC100077443Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
F7F063_ORNANNADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (570 aa)
SDHCUncharacterized protein. (89 aa)
COQ9Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (292 aa)
F7GBR6_ORNANUncharacterized protein. (90 aa)
F6RZD5_ORNANUncharacterized protein. (87 aa)
WDR93Uncharacterized protein. (690 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (652 aa)
PPP1R32Uncharacterized protein. (257 aa)
BIDUncharacterized protein. (138 aa)
F6YGN7_ORNAN4Fe-4S ferredoxin-type domain-containing protein. (303 aa)
AIFM2Apoptosis inducing factor mitochondria associated 2. (372 aa)
ETFRF1Electron transfer flavoprotein regulatory factor 1; Belongs to the complex I LYR family. (90 aa)
TAZTafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (262 aa)
F6UXN2_ORNANUncharacterized protein. (255 aa)
VSIG10LUncharacterized protein. (436 aa)
NDUFS7NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family. (170 aa)
COX4I1Cytochrome c oxidase subunit 4I1. (169 aa)
F7FC11_ORNANUncharacterized protein. (95 aa)
B3GNTL1UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1. (355 aa)
SLC25A18Solute carrier family 25 member 18; Belongs to the mitochondrial carrier (TC 2.A.29) family. (228 aa)
F6THK4_ORNANPUM-HD domain-containing protein. (429 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (314 aa)
F6RVT0_ORNANUncharacterized protein. (80 aa)
NDUFS1Uncharacterized protein; Belongs to the complex I 75 kDa subunit family. (400 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (202 aa)
ETFBETF domain-containing protein. (213 aa)
UQCRC1Ubiquinol-cytochrome c reductase core protein 1. (480 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (180 aa)
F7ERV2_ORNANzf-CHCC domain-containing protein. (107 aa)
F7D2R6_ORNANCytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (91 aa)
STEAP4STEAP4 metalloreductase. (469 aa)
COX7A2Cytochrome c oxidase subunit 7A2. (81 aa)
AFG1LAFG1 like ATPase. (530 aa)
CIAPIN1Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] (193 aa)
COX2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (230 aa)
COX1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (513 aa)
MT-ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (347 aa)
ND1NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (318 aa)
NDUFB9NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (165 aa)
F6VR07_ORNANProtein kinase domain-containing protein. (259 aa)
F6QXP8_ORNANUncharacterized protein. (154 aa)
F6QXN8_ORNANUncharacterized protein. (223 aa)
F7E0V4_ORNANUncharacterized protein. (57 aa)
F6TB01_ORNANETF domain-containing protein. (121 aa)
FDX2Uncharacterized protein. (48 aa)
F6X4C6_ORNANSURF1-like protein; Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. Belongs to the SURF1 family. (127 aa)
NDUFB6Uncharacterized protein. (121 aa)
K7E9B4_ORNANSURF1-like protein; Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. Belongs to the SURF1 family. (189 aa)
K7E9P9_ORNANUncharacterized protein. (309 aa)
UQCRQUbiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
K7EI71_ORNANSURF1-like protein; Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. Belongs to the SURF1 family. (122 aa)
COX3Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (261 aa)
MT-ND3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (115 aa)
ND4LNADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (98 aa)
MT-ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (460 aa)
MT-ND5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (604 aa)
ND6NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (166 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa)
ETFDHElectron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (619 aa)
NQO2N-ribosyldihydronicotinamide:quinone reductase 2. (230 aa)
F7EPH9_ORNANUncharacterized protein. (159 aa)
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
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