(23 nodes) Negative regulation of B cell proliferation network (Ornithorhynchus anatinus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	K7E9X2_ORNAN	Uncharacterized protein. (110 aa)
	TNFRSF13B	Uncharacterized protein. (246 aa)
	BTK	Tyrosine-protein kinase. (657 aa)
	F7DL14_ORNAN	Uncharacterized protein. (51 aa)
	LYN	Tyrosine-protein kinase. (514 aa)
	ATM	FAT domain-containing protein. (1029 aa)
	PKN1	Uncharacterized protein. (504 aa)
	F7BZD5_ORNAN	SH2 domain-containing protein. (871 aa)
	K7E960_ORNAN	Uncharacterized protein. (152 aa)
	TNFRSF21	TNF receptor superfamily member 21. (699 aa)
	IL10	Interleukin 10. (181 aa)
	F6T986_ORNAN	Tyrosine-protein kinase. (502 aa)
	CTLA4	Cytotoxic T-lymphocyte associated protein 4. (225 aa)
	F7EMW0_ORNAN	Uncharacterized protein. (86 aa)
	F7EMV6_ORNAN	TAN domain-containing protein. (316 aa)
	F7EMV0_ORNAN	TAN domain-containing protein. (121 aa)
	F7EE63_ORNAN	Uncharacterized protein. (73 aa)
	F6QB51_ORNAN	Uncharacterized protein. (91 aa)
	INPP5D	Uncharacterized protein. (221 aa)
	K7E7U9_ORNAN	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (77 aa)
	K7EAL5_ORNAN	FAT domain-containing protein. (153 aa)
	K7EA92_ORNAN	FAT domain-containing protein. (108 aa)
	RC3H1	Ring finger and CCCH-type domains 1. (1144 aa)

Your Current Organism:

Ornithorhynchus anatinus

NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATM	F7EMV0_ORNAN	ENSOANP00000009993	ENSOANP00000024948	FAT domain-containing protein.	TAN domain-containing protein.	0.901
ATM	F7EMV6_ORNAN	ENSOANP00000009993	ENSOANP00000024947	FAT domain-containing protein.	TAN domain-containing protein.	0.940
ATM	K7E960_ORNAN	ENSOANP00000009993	ENSOANP00000030067	FAT domain-containing protein.	Uncharacterized protein.	0.858
BTK	F6QB51_ORNAN	ENSOANP00000006710	ENSOANP00000025806	Tyrosine-protein kinase.	Uncharacterized protein.	0.439
BTK	F7EE63_ORNAN	ENSOANP00000006710	ENSOANP00000024999	Tyrosine-protein kinase.	Uncharacterized protein.	0.439
BTK	INPP5D	ENSOANP00000006710	ENSOANP00000026585	Tyrosine-protein kinase.	Uncharacterized protein.	0.537
BTK	LYN	ENSOANP00000006710	ENSOANP00000008740	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.982
CTLA4	IL10	ENSOANP00000017263	ENSOANP00000015289	Cytotoxic T-lymphocyte associated protein 4.	Interleukin 10.	0.596
CTLA4	LYN	ENSOANP00000017263	ENSOANP00000008740	Cytotoxic T-lymphocyte associated protein 4.	Tyrosine-protein kinase.	0.498
F6QB51_ORNAN	BTK	ENSOANP00000025806	ENSOANP00000006710	Uncharacterized protein.	Tyrosine-protein kinase.	0.439
F6QB51_ORNAN	F7EE63_ORNAN	ENSOANP00000025806	ENSOANP00000024999	Uncharacterized protein.	Uncharacterized protein.	0.900
F7BZD5_ORNAN	INPP5D	ENSOANP00000012394	ENSOANP00000026585	SH2 domain-containing protein.	Uncharacterized protein.	0.930
F7BZD5_ORNAN	LYN	ENSOANP00000012394	ENSOANP00000008740	SH2 domain-containing protein.	Tyrosine-protein kinase.	0.664
F7EE63_ORNAN	BTK	ENSOANP00000024999	ENSOANP00000006710	Uncharacterized protein.	Tyrosine-protein kinase.	0.439
F7EE63_ORNAN	F6QB51_ORNAN	ENSOANP00000024999	ENSOANP00000025806	Uncharacterized protein.	Uncharacterized protein.	0.900
F7EMV0_ORNAN	ATM	ENSOANP00000024948	ENSOANP00000009993	TAN domain-containing protein.	FAT domain-containing protein.	0.901
F7EMV0_ORNAN	K7E960_ORNAN	ENSOANP00000024948	ENSOANP00000030067	TAN domain-containing protein.	Uncharacterized protein.	0.932
F7EMV0_ORNAN	K7E9X2_ORNAN	ENSOANP00000024948	ENSOANP00000030329	TAN domain-containing protein.	Uncharacterized protein.	0.939
F7EMV0_ORNAN	K7EA92_ORNAN	ENSOANP00000024948	ENSOANP00000030449	TAN domain-containing protein.	FAT domain-containing protein.	0.938
F7EMV0_ORNAN	K7EAL5_ORNAN	ENSOANP00000024948	ENSOANP00000030572	TAN domain-containing protein.	FAT domain-containing protein.	0.938