(12 nodes) Retromer complex network (Ornithorhynchus anatinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SNX2	Sorting nexin 2. (489 aa)
	K7EGD6_ORNAN	Uncharacterized protein. (213 aa)
	K7EF66_ORNAN	Uncharacterized protein. (154 aa)
	SNX3	Sorting nexin 3. (164 aa)
	K7EEE5_ORNAN	Uncharacterized protein. (197 aa)
	F7GCF7_ORNAN	Vps5 domain-containing protein. (112 aa)
	F7AXN6_ORNAN	Uncharacterized protein. (646 aa)
	F6QH21_ORNAN	Uncharacterized protein. (341 aa)
	TBC1D5	Rab-GAP TBC domain-containing protein. (331 aa)
	VPS29	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (186 aa)
	VPS26A	VPS26, retromer complex component A. (302 aa)
	VPS35	Uncharacterized protein. (457 aa)

Your Current Organism:

Ornithorhynchus anatinus

NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6QH21_ORNAN	F7GCF7_ORNAN	ENSOANP00000013223	ENSOANP00000026627	Uncharacterized protein.	Vps5 domain-containing protein.	0.852
F6QH21_ORNAN	K7EF66_ORNAN	ENSOANP00000013223	ENSOANP00000032173	Uncharacterized protein.	Uncharacterized protein.	0.611
F6QH21_ORNAN	K7EGD6_ORNAN	ENSOANP00000013223	ENSOANP00000032593	Uncharacterized protein.	Uncharacterized protein.	0.575
F6QH21_ORNAN	SNX2	ENSOANP00000013223	ENSOANP00000015928	Uncharacterized protein.	Sorting nexin 2.	0.852
F6QH21_ORNAN	SNX3	ENSOANP00000013223	ENSOANP00000031959	Uncharacterized protein.	Sorting nexin 3.	0.956
F6QH21_ORNAN	TBC1D5	ENSOANP00000013223	ENSOANP00000007917	Uncharacterized protein.	Rab-GAP TBC domain-containing protein.	0.611
F6QH21_ORNAN	VPS26A	ENSOANP00000013223	ENSOANP00000006646	Uncharacterized protein.	VPS26, retromer complex component A.	0.977
F6QH21_ORNAN	VPS29	ENSOANP00000013223	ENSOANP00000007567	Uncharacterized protein.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.967
F6QH21_ORNAN	VPS35	ENSOANP00000013223	ENSOANP00000003564	Uncharacterized protein.	Uncharacterized protein.	0.950
F7AXN6_ORNAN	K7EEE5_ORNAN	ENSOANP00000018109	ENSOANP00000031902	Uncharacterized protein.	Uncharacterized protein.	0.900
F7GCF7_ORNAN	F6QH21_ORNAN	ENSOANP00000026627	ENSOANP00000013223	Vps5 domain-containing protein.	Uncharacterized protein.	0.852
F7GCF7_ORNAN	SNX2	ENSOANP00000026627	ENSOANP00000015928	Vps5 domain-containing protein.	Sorting nexin 2.	0.915
F7GCF7_ORNAN	SNX3	ENSOANP00000026627	ENSOANP00000031959	Vps5 domain-containing protein.	Sorting nexin 3.	0.731
F7GCF7_ORNAN	VPS26A	ENSOANP00000026627	ENSOANP00000006646	Vps5 domain-containing protein.	VPS26, retromer complex component A.	0.967
F7GCF7_ORNAN	VPS29	ENSOANP00000026627	ENSOANP00000007567	Vps5 domain-containing protein.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.966
F7GCF7_ORNAN	VPS35	ENSOANP00000026627	ENSOANP00000003564	Vps5 domain-containing protein.	Uncharacterized protein.	0.901
K7EEE5_ORNAN	F7AXN6_ORNAN	ENSOANP00000031902	ENSOANP00000018109	Uncharacterized protein.	Uncharacterized protein.	0.900
K7EF66_ORNAN	F6QH21_ORNAN	ENSOANP00000032173	ENSOANP00000013223	Uncharacterized protein.	Uncharacterized protein.	0.611
K7EF66_ORNAN	K7EGD6_ORNAN	ENSOANP00000032173	ENSOANP00000032593	Uncharacterized protein.	Uncharacterized protein.	0.948
K7EF66_ORNAN	TBC1D5	ENSOANP00000032173	ENSOANP00000007917	Uncharacterized protein.	Rab-GAP TBC domain-containing protein.	0.826