(25 nodes) Myoblast differentiation network (Ornithorhynchus anatinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MEGF10	Multiple EGF like domains 10. (792 aa)
	F6TH47_ORNAN	Uncharacterized protein; Belongs to the DEAD box helicase family. (338 aa)
	F7EV44_ORNAN	Uncharacterized protein. (900 aa)
	LGALS1	Galectin. (137 aa)
	DDX5	Uncharacterized protein; Belongs to the DEAD box helicase family. (614 aa)
	HINFP	Uncharacterized protein. (304 aa)
	MBNL1	Muscleblind like splicing regulator 1. (379 aa)
	LOC100080465	Uncharacterized protein. (472 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (819 aa)
	IGF1	Insulin like growth factor 1. (153 aa)
	F6TBC3_ORNAN	SAP domain-containing protein. (666 aa)
	TCF7L2	Transcription factor 7 like 2. (388 aa)
	PLEKHM3	PH domain-containing protein. (119 aa)
	NOTCH1	Notch receptor 1. (2492 aa)
	SDC1	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (314 aa)
	BCL9	Uncharacterized protein. (246 aa)
	F7B9S8_ORNAN	PAS domain-containing protein. (611 aa)
	F7DUQ1_ORNAN	Uncharacterized protein. (149 aa)
	RB1	Uncharacterized protein. (725 aa)
	F7FW04_ORNAN	Uncharacterized protein. (545 aa)
	K7ECV0_ORNAN	Uncharacterized protein. (83 aa)
	K7E9L3_ORNAN	Uncharacterized protein. (102 aa)
	K7E756_ORNAN	Uncharacterized protein. (93 aa)
	FGF6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (195 aa)
	F6UZ37_ORNAN	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (133 aa)

Your Current Organism:

Ornithorhynchus anatinus

NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL9	TCF7L2	ENSOANP00000024372	ENSOANP00000002523	Uncharacterized protein.	Transcription factor 7 like 2.	0.798
F7B9S8_ORNAN	F7DUQ1_ORNAN	ENSOANP00000024166	ENSOANP00000021755	PAS domain-containing protein.	Uncharacterized protein.	0.491
F7B9S8_ORNAN	NOTCH1	ENSOANP00000024166	ENSOANP00000004000	PAS domain-containing protein.	Notch receptor 1.	0.491
F7DUQ1_ORNAN	F7B9S8_ORNAN	ENSOANP00000021755	ENSOANP00000024166	Uncharacterized protein.	PAS domain-containing protein.	0.491
F7DUQ1_ORNAN	F7FW04_ORNAN	ENSOANP00000021755	ENSOANP00000021429	Uncharacterized protein.	Uncharacterized protein.	0.940
F7FW04_ORNAN	F7DUQ1_ORNAN	ENSOANP00000021429	ENSOANP00000021755	Uncharacterized protein.	Uncharacterized protein.	0.940
F7FW04_ORNAN	NOTCH1	ENSOANP00000021429	ENSOANP00000004000	Uncharacterized protein.	Notch receptor 1.	0.960
FGF6	SDC1	ENSOANP00000026402	ENSOANP00000001808	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.532
ITGB1	SDC1	ENSOANP00000009655	ENSOANP00000001808	Integrin beta; Belongs to the integrin beta chain family.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.491
NOTCH1	F7B9S8_ORNAN	ENSOANP00000004000	ENSOANP00000024166	Notch receptor 1.	PAS domain-containing protein.	0.491
NOTCH1	F7FW04_ORNAN	ENSOANP00000004000	ENSOANP00000021429	Notch receptor 1.	Uncharacterized protein.	0.960
SDC1	FGF6	ENSOANP00000001808	ENSOANP00000026402	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.532
SDC1	ITGB1	ENSOANP00000001808	ENSOANP00000009655	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	Integrin beta; Belongs to the integrin beta chain family.	0.491
TCF7L2	BCL9	ENSOANP00000002523	ENSOANP00000024372	Transcription factor 7 like 2.	Uncharacterized protein.	0.798