(44 nodes) Positive regulation of nuclear division network (Ornithorhynchus anatinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6UGB6_ORNAN	EGF-like domain-containing protein. (127 aa)
	F6Q038_ORNAN	Uncharacterized protein. (656 aa)
	F7G5E7_ORNAN	Uncharacterized protein. (358 aa)
	ANAPC7	Anaphase promoting complex subunit 7. (531 aa)
	NUSAP1	Uncharacterized protein. (451 aa)
	F6TGR1_ORNAN	TPR_REGION domain-containing protein. (364 aa)
	MAD2L1BP	MAD2L1 binding protein. (238 aa)
	F7EVG8_ORNAN	Receptor protein-tyrosine kinase. (1063 aa)
	F7FAA9_ORNAN	Cullin domain-containing protein; Belongs to the cullin family. (91 aa)
	PHIP	Uncharacterized protein. (1789 aa)
	ANAPC5	Uncharacterized protein. (438 aa)
	F7BY41_ORNAN	Uncharacterized protein. (290 aa)
	WNT4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (233 aa)
	HOXA13	Homeobox A13. (351 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1096 aa)
	dmrt1	Doublesex and mab-3 related transcription factor 1. (93 aa)
	CDC27	Uncharacterized protein. (400 aa)
	EDN1	Endothelin 1. (204 aa)
	BTC	Betacellulin. (182 aa)
	EREG	Epiregulin. (163 aa)
	EPGN	Epithelial mitogen. (114 aa)
	RB1	Uncharacterized protein. (725 aa)
	NSMCE2	SP-RING-type domain-containing protein. (91 aa)
	K7EH90_ORNAN	ANAPC8 domain-containing protein. (143 aa)
	ENSOANP00000032545	annotation not available (51 aa)
	K7EDR4_ORNAN	Bromo domain-containing protein. (138 aa)
	K7ECV0_ORNAN	Uncharacterized protein. (83 aa)
	NPM2	Nucleoplasmin domain-containing protein. (221 aa)
	K7EAK0_ORNAN	Uncharacterized protein. (142 aa)
	K7EAD1_ORNAN	DAGKc domain-containing protein. (48 aa)
	CDC16	TPR_REGION domain-containing protein. (313 aa)
	MSX1	Msh homeobox 1. (304 aa)
	ANAPC11	Uncharacterized protein. (96 aa)
	F6YQH5_ORNAN	Uncharacterized protein. (113 aa)
	F7FIT2_ORNAN	Uncharacterized protein. (235 aa)
	PDGFB	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (212 aa)
	IGF1	Insulin like growth factor 1. (153 aa)
	F7E3J1_ORNAN	CDT1 domain-containing protein. (445 aa)
	CUL3	Cullin 3; Belongs to the cullin family. (642 aa)
	SPHK1	Uncharacterized protein. (270 aa)
	SMPD3	Sphingomyelin phosphodiesterase 3. (664 aa)
	PIWIL2	Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family. (971 aa)
	RGCC	Regulator of cell cycle. (172 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (290 aa)

Your Current Organism:

Ornithorhynchus anatinus

NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANAPC11	ANAPC5	ENSOANP00000029341	ENSOANP00000001245	Uncharacterized protein.	Uncharacterized protein.	0.996
ANAPC11	ANAPC7	ENSOANP00000029341	ENSOANP00000007565	Uncharacterized protein.	Anaphase promoting complex subunit 7.	0.994
ANAPC11	CDC16	ENSOANP00000029341	ENSOANP00000030411	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.996
ANAPC11	CDC27	ENSOANP00000029341	ENSOANP00000011546	Uncharacterized protein.	Uncharacterized protein.	0.996
ANAPC11	F6TGR1_ORNAN	ENSOANP00000029341	ENSOANP00000005396	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.962
ANAPC11	F7E3J1_ORNAN	ENSOANP00000029341	ENSOANP00000021918	Uncharacterized protein.	CDT1 domain-containing protein.	0.560
ANAPC11	F7FIT2_ORNAN	ENSOANP00000029341	ENSOANP00000026083	Uncharacterized protein.	Uncharacterized protein.	0.962
ANAPC11	K7EAK0_ORNAN	ENSOANP00000029341	ENSOANP00000030557	Uncharacterized protein.	Uncharacterized protein.	0.962
ANAPC11	K7ECV0_ORNAN	ENSOANP00000029341	ENSOANP00000031357	Uncharacterized protein.	Uncharacterized protein.	0.496
ANAPC11	K7EDR4_ORNAN	ENSOANP00000029341	ENSOANP00000031671	Uncharacterized protein.	Bromo domain-containing protein.	0.416
ANAPC11	K7EH90_ORNAN	ENSOANP00000029341	ENSOANP00000032897	Uncharacterized protein.	ANAPC8 domain-containing protein.	0.998
ANAPC11	PHIP	ENSOANP00000029341	ENSOANP00000001488	Uncharacterized protein.	Uncharacterized protein.	0.416
ANAPC11	RB1	ENSOANP00000029341	ENSOANP00000024505	Uncharacterized protein.	Uncharacterized protein.	0.496
ANAPC5	ANAPC11	ENSOANP00000001245	ENSOANP00000029341	Uncharacterized protein.	Uncharacterized protein.	0.996
ANAPC5	ANAPC7	ENSOANP00000001245	ENSOANP00000007565	Uncharacterized protein.	Anaphase promoting complex subunit 7.	0.996
ANAPC5	CDC16	ENSOANP00000001245	ENSOANP00000030411	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.988
ANAPC5	CDC27	ENSOANP00000001245	ENSOANP00000011546	Uncharacterized protein.	Uncharacterized protein.	0.988
ANAPC5	F6TGR1_ORNAN	ENSOANP00000001245	ENSOANP00000005396	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.948
ANAPC5	F7E3J1_ORNAN	ENSOANP00000001245	ENSOANP00000021918	Uncharacterized protein.	CDT1 domain-containing protein.	0.488
ANAPC5	F7FIT2_ORNAN	ENSOANP00000001245	ENSOANP00000026083	Uncharacterized protein.	Uncharacterized protein.	0.949