(12 nodes) Hepatocyte differentiation network (Ornithorhynchus anatinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PCK1	Phosphoenolpyruvate carboxykinase 1. (695 aa)
	PROX1	Prospero homeobox 1. (781 aa)
	PCK2	Phosphoenolpyruvate carboxykinase 2, mitochondrial. (662 aa)
	E2F7	Uncharacterized protein. (408 aa)
	F6WWD2_ORNAN	Uncharacterized protein. (304 aa)
	F6PUY7_ORNAN	Uncharacterized protein. (451 aa)
	F7FJY7_ORNAN	NTR domain-containing protein. (173 aa)
	E2F8	E2F transcription factor 8. (815 aa)
	CPS1	ATP-grasp domain-containing protein. (704 aa)
	ANXA1	Annexin. (357 aa)
	SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1. (348 aa)
	F7FKQ1_ORNAN	Glutamine amidotransferase type-1 domain-containing protein. (520 aa)

Your Current Organism:

Ornithorhynchus anatinus

NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CPS1	F7FKQ1_ORNAN	ENSOANP00000017521	ENSOANP00000017520	ATP-grasp domain-containing protein.	Glutamine amidotransferase type-1 domain-containing protein.	0.922
E2F7	E2F8	ENSOANP00000011861	ENSOANP00000017888	Uncharacterized protein.	E2F transcription factor 8.	0.668
E2F7	F6WWD2_ORNAN	ENSOANP00000011861	ENSOANP00000011859	Uncharacterized protein.	Uncharacterized protein.	0.900
E2F8	E2F7	ENSOANP00000017888	ENSOANP00000011861	E2F transcription factor 8.	Uncharacterized protein.	0.668
E2F8	F6WWD2_ORNAN	ENSOANP00000017888	ENSOANP00000011859	E2F transcription factor 8.	Uncharacterized protein.	0.679
F6WWD2_ORNAN	E2F7	ENSOANP00000011859	ENSOANP00000011861	Uncharacterized protein.	Uncharacterized protein.	0.900
F6WWD2_ORNAN	E2F8	ENSOANP00000011859	ENSOANP00000017888	Uncharacterized protein.	E2F transcription factor 8.	0.679
F7FKQ1_ORNAN	CPS1	ENSOANP00000017520	ENSOANP00000017521	Glutamine amidotransferase type-1 domain-containing protein.	ATP-grasp domain-containing protein.	0.922
PCK1	PCK2	ENSOANP00000014739	ENSOANP00000012548	Phosphoenolpyruvate carboxykinase 1.	Phosphoenolpyruvate carboxykinase 2, mitochondrial.	0.907
PCK2	PCK1	ENSOANP00000012548	ENSOANP00000014739	Phosphoenolpyruvate carboxykinase 2, mitochondrial.	Phosphoenolpyruvate carboxykinase 1.	0.907