STRINGSTRING
CPSF7 CPSF7 PIWIL2 PIWIL2 ANGEL1 ANGEL1 LOC100083007 LOC100083007 CNOT7 CNOT7 CNOT6 CNOT6 F6WAA7_ORNAN F6WAA7_ORNAN DIS3 DIS3 TBL3 TBL3 F6SU25_ORNAN F6SU25_ORNAN DIS3L DIS3L MRPL44 MRPL44 SAMHD1 SAMHD1 F6S170_ORNAN F6S170_ORNAN KRI1 KRI1 RNASEH2A RNASEH2A PAN3 PAN3 TSR1 TSR1 CPSF3 CPSF3 ERI1 ERI1 ANGEL2 ANGEL2 EXOSC9 EXOSC9 TSEN34 TSEN34 K7EHK2_ORNAN K7EHK2_ORNAN K7EI68_ORNAN K7EI68_ORNAN EXOSC7 EXOSC7 XRN1 XRN1 PCF11 PCF11 ISG20 ISG20 K7E856_ORNAN K7E856_ORNAN K7E841_ORNAN K7E841_ORNAN K7E822_ORNAN K7E822_ORNAN K7E7W7_ORNAN K7E7W7_ORNAN K7E7Q9_ORNAN K7E7Q9_ORNAN B4GALNT4 B4GALNT4 K7E750_ORNAN K7E750_ORNAN ENSOANP00000029244 ENSOANP00000029244 RNASET2 RNASET2 RPP14 RPP14 RIDA RIDA CNOT8 CNOT8 CNOT2 CNOT2 F7EI45_ORNAN F7EI45_ORNAN SMG6 SMG6 F7ETK8_ORNAN F7ETK8_ORNAN POP4 POP4 F7BMQ4_ORNAN F7BMQ4_ORNAN F7CBH6_ORNAN F7CBH6_ORNAN PARN PARN RNASEK RNASEK F6VVM7_ORNAN F6VVM7_ORNAN DIS3L2 DIS3L2 F7G9I3_ORNAN F7G9I3_ORNAN F7G9J6_ORNAN F7G9J6_ORNAN XRN2 XRN2 EXOSC8 EXOSC8 ZC3H12C ZC3H12C CPSF6 CPSF6 NUDT12 NUDT12 F6VKJ3_ORNAN F6VKJ3_ORNAN PAN2 PAN2 MARF1 MARF1 HELZ2 HELZ2 UTP23 UTP23 F6S3B0_ORNAN F6S3B0_ORNAN F6TV77_ORNAN F6TV77_ORNAN CSTF2 CSTF2 CPSF2 CPSF2 CNOT6L CNOT6L RPP30 RPP30 RPS21 RPS21 ISG20L2 ISG20L2 EXD2-2 EXD2-2 F6TRH5_ORNAN F6TRH5_ORNAN ZC3H12A ZC3H12A NCBP1 NCBP1 RNASE4 RNASE4 TTC38 TTC38 POP5 POP5 REXO2 REXO2 POP7 POP7 F7F8E2_ORNAN F7F8E2_ORNAN F7G348_ORNAN F7G348_ORNAN RPP40 RPP40 EXOSC2 EXOSC2 SWT1 SWT1 RNASEL RNASEL EXOSC3 EXOSC3 SND1 SND1 BMS1 BMS1 N4BP1 N4BP1 ENSOANP00000032946 ENSOANP00000032946 KPNB1 KPNB1 F7BCF3_ORNAN F7BCF3_ORNAN AGO2 AGO2 F6UFC4_ORNAN F6UFC4_ORNAN CPSF4 CPSF4 DBR1 DBR1 FEN1 FEN1 ERN1 ERN1 ELAC1 ELAC1 K7E942_ORNAN K7E942_ORNAN K7E9A0_ORNAN K7E9A0_ORNAN POP1 POP1 K7E9F0_ORNAN K7E9F0_ORNAN K7E9F3_ORNAN K7E9F3_ORNAN LRRC27 LRRC27 K7E9U3_ORNAN K7E9U3_ORNAN K7EA36_ORNAN K7EA36_ORNAN K7EAA0_ORNAN K7EAA0_ORNAN ERN1-2 ERN1-2 K7EAT6_ORNAN K7EAT6_ORNAN K7EBH5_ORNAN K7EBH5_ORNAN ERN2 ERN2 TOE1-2 TOE1-2 K7ECS6_ORNAN K7ECS6_ORNAN K7ED14_ORNAN K7ED14_ORNAN K7ED54_ORNAN K7ED54_ORNAN K7EDQ7_ORNAN K7EDQ7_ORNAN ENSOANP00000031697 ENSOANP00000031697 K7EE54_ORNAN K7EE54_ORNAN K7EFB5_ORNAN K7EFB5_ORNAN K7EFE1_ORNAN K7EFE1_ORNAN ELAC2 ELAC2 ENSOANP00000032545 ENSOANP00000032545 NOB1 NOB1 K7EGF0_ORNAN K7EGF0_ORNAN F6YL78_ORNAN F6YL78_ORNAN ABT1 ABT1 POLR3K POLR3K ERI2 ERI2 LACTB2 LACTB2 PRORP PRORP NOCT NOCT YBEY YBEY EXOSC10 EXOSC10 F7A1N5_ORNAN F7A1N5_ORNAN F6WQY8_ORNAN F6WQY8_ORNAN RCL1 RCL1 F6RCX8_ORNAN F6RCX8_ORNAN PDE12 PDE12 NUDT21 NUDT21 EXD2 EXD2 F7FZR1_ORNAN F7FZR1_ORNAN RRS1 RRS1 F7FVF8_ORNAN F7FVF8_ORNAN PNLDC1 PNLDC1 USB1 USB1 CNOT1 CNOT1 DICER1 DICER1 PIWIL1 PIWIL1 TOE1 TOE1 LOC114810098 LOC114810098 NOL9 NOL9 TSEN2 TSEN2 F7GEV5_ORNAN F7GEV5_ORNAN PNPT1 PNPT1 DCP2 DCP2 B4GALNT3 B4GALNT3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CPSF7Cleavage and polyadenylation specific factor 7. (467 aa)
PIWIL2Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family. (971 aa)
ANGEL1Angel homolog 1. (672 aa)
LOC100083007Uncharacterized protein. (512 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (285 aa)
CNOT6CCR4-NOT transcription complex subunit 6. (557 aa)
F6WAA7_ORNANRNB domain-containing protein. (265 aa)
DIS3DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1007 aa)
TBL3Transducin beta like 3. (787 aa)
F6SU25_ORNANEST1_DNA_bind domain-containing protein. (60 aa)
DIS3LDIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (994 aa)
MRPL44Mitochondrial ribosomal protein L44. (313 aa)
SAMHD1HD domain-containing protein. (141 aa)
F6S170_ORNANUncharacterized protein. (272 aa)
KRI1Kri1_C domain-containing protein. (481 aa)
RNASEH2ARibonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (300 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (671 aa)
TSR1TSR1 ribosome maturation factor. (728 aa)
CPSF3Cleavage and polyadenylation specific factor 3. (564 aa)
ERI1Exoribonuclease 1. (316 aa)
ANGEL2Angel homolog 2. (523 aa)
EXOSC9Exosome component 9. (439 aa)
TSEN34tRNA_int_endo domain-containing protein. (219 aa)
K7EHK2_ORNANUncharacterized protein. (79 aa)
K7EI68_ORNANUncharacterized protein. (264 aa)
EXOSC7Exosome component 7. (277 aa)
XRN15'-3' exoribonuclease 1. (1598 aa)
PCF11PCF11 cleavage and polyadenylation factor subunit. (1455 aa)
ISG20Interferon stimulated exonuclease gene 20. (184 aa)
K7E856_ORNANUncharacterized protein. (64 aa)
K7E841_ORNANUncharacterized protein. (512 aa)
K7E822_ORNANNot1 domain-containing protein. (177 aa)
K7E7W7_ORNANRrp44_CSD1 domain-containing protein. (82 aa)
K7E7Q9_ORNANR3H domain-containing protein. (214 aa)
B4GALNT4Uncharacterized protein. (72 aa)
K7E750_ORNANUncharacterized protein. (68 aa)
ENSOANP00000029244annotation not available (72 aa)
RNASET2Uncharacterized protein; Belongs to the RNase T2 family. (249 aa)
RPP14Uncharacterized protein. (115 aa)
RIDAReactive intermediate imine deaminase A homolog. (133 aa)
CNOT8Uncharacterized protein. (292 aa)
CNOT2CCR4-NOT transcription complex subunit 2. (550 aa)
F7EI45_ORNANXendoU domain-containing protein. (207 aa)
SMG6Uncharacterized protein. (452 aa)
F7ETK8_ORNANRNase_Zc3h12a domain-containing protein. (163 aa)
POP4POP4 domain-containing protein. (93 aa)
F7BMQ4_ORNANFip1 domain-containing protein. (569 aa)
F7CBH6_ORNANUncharacterized protein. (875 aa)
PARNRNA_bind domain-containing protein. (388 aa)
RNASEKUncharacterized protein. (104 aa)
F6VVM7_ORNANUncharacterized protein. (77 aa)
DIS3L2RNB domain-containing protein. (233 aa)
F7G9I3_ORNANUncharacterized protein. (767 aa)
F7G9J6_ORNANUncharacterized protein. (384 aa)
XRN25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (950 aa)
EXOSC8Exosome component 8. (305 aa)
ZC3H12CZinc finger CCCH-type containing 12C. (633 aa)
CPSF6Cleavage and polyadenylation specific factor 6. (530 aa)
NUDT12Nudix hydrolase 12. (460 aa)
F6VKJ3_ORNANUBA_6 domain-containing protein. (192 aa)
PAN2Poly(A) specific ribonuclease subunit PAN2. (993 aa)
MARF1Uncharacterized protein. (1753 aa)
HELZ2RNB domain-containing protein. (1963 aa)
UTP23UTP23 small subunit processome component. (237 aa)
F6S3B0_ORNANHexosyltransferase. (310 aa)
F6TV77_ORNANUncharacterized protein. (229 aa)
CSTF2Cleavage stimulation factor subunit 2. (627 aa)
CPSF2Cleavage and polyadenylation specificity factor subunit 2. (782 aa)
CNOT6LCCR4-NOT transcription complex subunit 6 like. (550 aa)
RPP30Ribonuclease P/MRP subunit p30. (267 aa)
RPS21Ribosomal protein S21. (107 aa)
ISG20L2Exonuclease domain-containing protein. (99 aa)
EXD2-2Uncharacterized protein. (128 aa)
F6TRH5_ORNANXendoU domain-containing protein. (191 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (603 aa)
NCBP1Nuclear cap binding protein subunit 1. (623 aa)
RNASE4Ribonuclease A family member 4; Belongs to the pancreatic ribonuclease family. (149 aa)
TTC38Tetratricopeptide repeat domain 38. (466 aa)
POP5Uncharacterized protein. (114 aa)
REXO2RNA exonuclease 2. (238 aa)
POP7Ribonuclease P protein subunit p20; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences; Belongs to the histone-like Alba family. (129 aa)
F7F8E2_ORNANRNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (203 aa)
F7G348_ORNANUncharacterized protein. (708 aa)
RPP40Ribonuclease P/MRP subunit p40. (304 aa)
EXOSC2Exosome component 2. (293 aa)
SWT1PINc domain-containing protein. (792 aa)
RNASELUncharacterized protein. (694 aa)
EXOSC3Exosome component 3. (254 aa)
SND1Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. (909 aa)
BMS1Bms1-type G domain-containing protein. (1284 aa)
N4BP1NEDD4 binding protein 1. (936 aa)
ENSOANP00000032946annotation not available (60 aa)
KPNB1Uncharacterized protein. (242 aa)
F7BCF3_ORNANProtein kinase domain-containing protein. (406 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (860 aa)
F6UFC4_ORNANRNase_Zc3h12a domain-containing protein. (637 aa)
CPSF4Cleavage and polyadenylation specific factor 4. (234 aa)
DBR1Debranching RNA lariats 1. (490 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (387 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (900 aa)
ELAC1ElaC ribonuclease Z 1. (349 aa)
K7E942_ORNANGAGE domain-containing protein. (76 aa)
K7E9A0_ORNANUncharacterized protein. (167 aa)
POP1Uncharacterized protein. (274 aa)
K7E9F0_ORNANLactamase_B domain-containing protein. (176 aa)
K7E9F3_ORNANPINc domain-containing protein. (328 aa)
LRRC27Uncharacterized protein. (184 aa)
K7E9U3_ORNANCLP1_P domain-containing protein. (153 aa)
K7EA36_ORNANUncharacterized protein. (147 aa)
K7EAA0_ORNANPiwi domain-containing protein. (106 aa)
ERN1-2Uncharacterized protein. (67 aa)
K7EAT6_ORNANOB_Dis3 domain-containing protein. (117 aa)
K7EBH5_ORNANLactamase_B domain-containing protein. (236 aa)
ERN2Uncharacterized protein. (88 aa)
TOE1-2Target of EGR1 protein 1. (68 aa)
K7ECS6_ORNANUncharacterized protein. (100 aa)
K7ED14_ORNANUncharacterized protein. (168 aa)
K7ED54_ORNANPAZ domain-containing protein. (86 aa)
K7EDQ7_ORNANUncharacterized protein. (207 aa)
ENSOANP00000031697annotation not available (104 aa)
K7EE54_ORNANUncharacterized protein. (86 aa)
K7EFB5_ORNANUncharacterized protein. (159 aa)
K7EFE1_ORNANUncharacterized protein. (106 aa)
ELAC2Uncharacterized protein. (144 aa)
ENSOANP00000032545annotation not available (51 aa)
NOB1Uncharacterized protein. (123 aa)
K7EGF0_ORNAN3'-5' exonuclease domain-containing protein. (79 aa)
F6YL78_ORNANC3H1-type domain-containing protein. (527 aa)
ABT1Uncharacterized protein. (211 aa)
POLR3KRNA polymerase III subunit K. (72 aa)
ERI2Exonuclease domain-containing protein. (699 aa)
LACTB2Lactamase beta 2. (237 aa)
PRORPPRORP domain-containing protein. (448 aa)
NOCTNocturnin. (437 aa)
YBEYYbeY metalloendoribonuclease. (165 aa)
EXOSC10Exosome component 10. (898 aa)
F7A1N5_ORNANRTC domain-containing protein. (132 aa)
F6WQY8_ORNANRNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (150 aa)
RCL1Uncharacterized protein. (253 aa)
F6RCX8_ORNANRMMBL domain-containing protein. (500 aa)
PDE12Phosphodiesterase 12. (552 aa)
NUDT21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa)
EXD2Exonuclease 3'-5' domain containing 2. (498 aa)
F7FZR1_ORNANRRM domain-containing protein. (500 aa)
RRS1Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (372 aa)
F7FVF8_ORNANUncharacterized protein. (80 aa)
PNLDC1PARN like, ribonuclease domain containing 1. (507 aa)
USB1U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate; Belongs to the 2H phosphoesterase superfamily. USB1 family. (239 aa)
CNOT1Uncharacterized protein. (2149 aa)
DICER1Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1921 aa)
PIWIL1Uncharacterized protein; Belongs to the argonaute family. (808 aa)
TOE1C3H1-type domain-containing protein. (464 aa)
LOC114810098Uncharacterized protein. (280 aa)
NOL9CLP1_P domain-containing protein. (466 aa)
TSEN2tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] (432 aa)
F7GEV5_ORNANNuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (108 aa)
PNPT1S1 motif domain-containing protein. (704 aa)
DCP2Decapping mRNA 2. (446 aa)
B4GALNT3Beta-1,4-N-acetylgalactosaminyltransferase; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'- diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. (925 aa)
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
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