(37 nodes) Energy homeostasis network (Ornithorhynchus anatinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LEPR	Uncharacterized protein. (1155 aa)
	FMO3	Dimethylaniline monooxygenase [N-oxide-forming]. (540 aa)
	FMO2	Dimethylaniline monooxygenase [N-oxide-forming]. (535 aa)
	FMO1	Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
	FMO4	Dimethylaniline monooxygenase [N-oxide-forming]. (563 aa)
	TSKU	Tsukushi, small leucine rich proteoglycan. (356 aa)
	FLCN	UDENN FLCN/SMCR8-type domain-containing protein. (579 aa)
	METRNL	Meteorin like, glial cell differentiation regulator. (261 aa)
	PPARGC1A	PPARG coactivator 1 alpha. (795 aa)
	F6Q195_ORNAN	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (505 aa)
	MEX3C	Mex-3 RNA binding family member C. (408 aa)
	F6U8Z0_ORNAN	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (515 aa)
	PRCP	Prolylcarboxypeptidase. (449 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
	F7BY83_ORNAN	Uncharacterized protein. (63 aa)
	SQSTM1	Sequestosome 1. (434 aa)
	F6W2G5_ORNAN	Uncharacterized protein. (437 aa)
	PASK	Uncharacterized protein. (1305 aa)
	F6XGM3_ORNAN	STAT_bind domain-containing protein. (193 aa)
	NR1D2	Nuclear receptor subfamily 1 group D member 2. (590 aa)
	F7E5J9_ORNAN	Uncharacterized protein. (90 aa)
	DLL1	EGF-like domain-containing protein. (52 aa)
	ENSOANP00000031210	annotation not available (90 aa)
	MRAP2	Uncharacterized protein. (76 aa)
	STAT3	STAT_alpha domain-containing protein. (156 aa)
	K7E8H2_ORNAN	A_deaminase domain-containing protein. (81 aa)
	K7E6Z5_ORNAN	M20_dimer domain-containing protein. (164 aa)
	MLXIPL	Uncharacterized protein. (122 aa)
	PRKAA1	Non-specific serine/threonine protein kinase. (575 aa)
	SGIP1	Uncharacterized protein. (158 aa)
	ENSOANP00000026171	annotation not available (132 aa)
	NR4A3	Nuclear receptor subfamily 4 group A member 3. (562 aa)
	PM20D1	Uncharacterized protein. (270 aa)
	F7E554_ORNAN	TORC_M domain-containing protein. (197 aa)
	SIRT1	Uncharacterized protein. (226 aa)
	NMU	NMU domain-containing protein. (132 aa)
	SLC35D3	Uncharacterized protein. (226 aa)

Your Current Organism:

Ornithorhynchus anatinus

NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOANP00000026171	ENSOANP00000031210	ENSOANP00000026171	ENSOANP00000031210	annotation not available	annotation not available	0.900
ENSOANP00000031210	ENSOANP00000026171	ENSOANP00000031210	ENSOANP00000026171	annotation not available	annotation not available	0.900
F6Q195_ORNAN	SGIP1	ENSOANP00000010925	ENSOANP00000027833	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	Uncharacterized protein.	0.900
F6U8Z0_ORNAN	F7E5J9_ORNAN	ENSOANP00000016505	ENSOANP00000007225	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.	Uncharacterized protein.	0.433
F6XGM3_ORNAN	LEPR	ENSOANP00000025933	ENSOANP00000000644	STAT_bind domain-containing protein.	Uncharacterized protein.	0.453
F6XGM3_ORNAN	STAT3	ENSOANP00000025933	ENSOANP00000030106	STAT_bind domain-containing protein.	STAT_alpha domain-containing protein.	0.938
F7E5J9_ORNAN	F6U8Z0_ORNAN	ENSOANP00000007225	ENSOANP00000016505	Uncharacterized protein.	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.	0.433
K7E6Z5_ORNAN	PM20D1	ENSOANP00000029302	ENSOANP00000004689	M20_dimer domain-containing protein.	Uncharacterized protein.	0.950
LEPR	F6XGM3_ORNAN	ENSOANP00000000644	ENSOANP00000025933	Uncharacterized protein.	STAT_bind domain-containing protein.	0.453
LEPR	STAT3	ENSOANP00000000644	ENSOANP00000030106	Uncharacterized protein.	STAT_alpha domain-containing protein.	0.559
METRNL	SIRT1	ENSOANP00000009273	ENSOANP00000007323	Meteorin like, glial cell differentiation regulator.	Uncharacterized protein.	0.420
NR1D2	NR4A3	ENSOANP00000005607	ENSOANP00000003373	Nuclear receptor subfamily 1 group D member 2.	Nuclear receptor subfamily 4 group A member 3.	0.423
NR4A3	NR1D2	ENSOANP00000003373	ENSOANP00000005607	Nuclear receptor subfamily 4 group A member 3.	Nuclear receptor subfamily 1 group D member 2.	0.423
PM20D1	K7E6Z5_ORNAN	ENSOANP00000004689	ENSOANP00000029302	Uncharacterized protein.	M20_dimer domain-containing protein.	0.950
PPARGC1A	PRKAA1	ENSOANP00000010663	ENSOANP00000028274	PPARG coactivator 1 alpha.	Non-specific serine/threonine protein kinase.	0.941
PPARGC1A	SIRT1	ENSOANP00000010663	ENSOANP00000007323	PPARG coactivator 1 alpha.	Uncharacterized protein.	0.980
PRKAA1	PPARGC1A	ENSOANP00000028274	ENSOANP00000010663	Non-specific serine/threonine protein kinase.	PPARG coactivator 1 alpha.	0.941
PRKAA1	SIRT1	ENSOANP00000028274	ENSOANP00000007323	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.517
SGIP1	F6Q195_ORNAN	ENSOANP00000027833	ENSOANP00000010925	Uncharacterized protein.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.900
SIRT1	METRNL	ENSOANP00000007323	ENSOANP00000009273	Uncharacterized protein.	Meteorin like, glial cell differentiation regulator.	0.420