STRINGSTRING
NOTCH1 NOTCH1 ITGB1 ITGB1 K7EEE4_ORNAN K7EEE4_ORNAN ENSOANP00000031210 ENSOANP00000031210 K7E7K6_ORNAN K7E7K6_ORNAN F7EBT7_ORNAN F7EBT7_ORNAN ENSOANP00000026171 ENSOANP00000026171 ENSOANP00000023661 ENSOANP00000023661 CAV1 CAV1 F7C3G9_ORNAN F7C3G9_ORNAN PIK3CA PIK3CA F7DUQ1_ORNAN F7DUQ1_ORNAN PTRH2 PTRH2 ITGA5 ITGA5 SNAI2 SNAI2 PTK2 PTK2 NTRK2 NTRK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NOTCH1Notch receptor 1. (2492 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (819 aa)
K7EEE4_ORNANUncharacterized protein. (161 aa)
ENSOANP00000031210annotation not available (90 aa)
K7E7K6_ORNANProtein kinase domain-containing protein. (111 aa)
F7EBT7_ORNANWD_REPEATS_REGION domain-containing protein. (264 aa)
ENSOANP00000026171annotation not available (132 aa)
ENSOANP00000023661annotation not available (113 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (113 aa)
F7C3G9_ORNANProtein-serine/threonine kinase. (390 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
F7DUQ1_ORNANUncharacterized protein. (149 aa)
PTRH2Peptidyl-tRNA hydrolase 2. (179 aa)
ITGA5Integrin_alpha2 domain-containing protein. (543 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1142 aa)
NTRK2Ig-like domain-containing protein. (415 aa)
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
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