(20 nodes) RHOJ GTPase cycle network (Ornithorhynchus anatinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	K7EDH1_ORNAN	DH domain-containing protein. (106 aa)
	PIK3R2	Uncharacterized protein. (724 aa)
	ARHGAP35	Rho GTPase activating protein 35. (1421 aa)
	PIK3R1	SH2 domain-containing protein. (230 aa)
	ARHGAP26	Uncharacterized protein. (657 aa)
	F7BVI1_ORNAN	Rho-GAP domain-containing protein. (284 aa)
	ARHGAP21	Rho GTPase activating protein 21. (1942 aa)
	F7G762_ORNAN	Uncharacterized protein. (158 aa)
	TRIO	Trio Rho guanine nucleotide exchange factor. (3046 aa)
	F7BIB5_ORNAN	WH2 domain-containing protein. (448 aa)
	OCRL	Rho-GAP domain-containing protein. (850 aa)
	F7E214_ORNAN	Uncharacterized protein. (359 aa)
	ARHGAP5	Rho GTPase activating protein 5. (1500 aa)
	F6WWU5_ORNAN	DEP domain-containing protein. (475 aa)
	F7BU59_ORNAN	Uncharacterized protein. (406 aa)
	F7EB29_ORNAN	DHR-2 domain-containing protein; Belongs to the DOCK family. (294 aa)
	ARHGAP1	Rho GTPase activating protein 1. (422 aa)
	K7ED18_ORNAN	Rho-GAP domain-containing protein. (96 aa)
	OPHN1	Uncharacterized protein. (130 aa)
	ENSOANP00000032985	annotation not available (62 aa)

Your Current Organism:

Ornithorhynchus anatinus

NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP1	ENSOANP00000032985	ENSOANP00000028117	ENSOANP00000032985	Rho GTPase activating protein 1.	annotation not available	0.410
ARHGAP1	F7BU59_ORNAN	ENSOANP00000028117	ENSOANP00000023980	Rho GTPase activating protein 1.	Uncharacterized protein.	0.522
ARHGAP1	F7G762_ORNAN	ENSOANP00000028117	ENSOANP00000014480	Rho GTPase activating protein 1.	Uncharacterized protein.	0.610
ARHGAP1	OCRL	ENSOANP00000028117	ENSOANP00000019054	Rho GTPase activating protein 1.	Rho-GAP domain-containing protein.	0.410
ARHGAP35	ARHGAP5	ENSOANP00000005427	ENSOANP00000022136	Rho GTPase activating protein 35.	Rho GTPase activating protein 5.	0.901
ARHGAP35	F7G762_ORNAN	ENSOANP00000005427	ENSOANP00000014480	Rho GTPase activating protein 35.	Uncharacterized protein.	0.472
ARHGAP5	ARHGAP35	ENSOANP00000022136	ENSOANP00000005427	Rho GTPase activating protein 5.	Rho GTPase activating protein 35.	0.901
ARHGAP5	F7G762_ORNAN	ENSOANP00000022136	ENSOANP00000014480	Rho GTPase activating protein 5.	Uncharacterized protein.	0.472
ENSOANP00000032985	ARHGAP1	ENSOANP00000032985	ENSOANP00000028117	annotation not available	Rho GTPase activating protein 1.	0.410
F7BIB5_ORNAN	F7BU59_ORNAN	ENSOANP00000018957	ENSOANP00000023980	WH2 domain-containing protein.	Uncharacterized protein.	0.956
F7BU59_ORNAN	ARHGAP1	ENSOANP00000023980	ENSOANP00000028117	Uncharacterized protein.	Rho GTPase activating protein 1.	0.522
F7BU59_ORNAN	F7BIB5_ORNAN	ENSOANP00000023980	ENSOANP00000018957	Uncharacterized protein.	WH2 domain-containing protein.	0.956
F7BU59_ORNAN	F7EB29_ORNAN	ENSOANP00000023980	ENSOANP00000026778	Uncharacterized protein.	DHR-2 domain-containing protein; Belongs to the DOCK family.	0.618
F7BU59_ORNAN	F7G762_ORNAN	ENSOANP00000023980	ENSOANP00000014480	Uncharacterized protein.	Uncharacterized protein.	0.598
F7BU59_ORNAN	PIK3R1	ENSOANP00000023980	ENSOANP00000007081	Uncharacterized protein.	SH2 domain-containing protein.	0.425
F7E214_ORNAN	F7EB29_ORNAN	ENSOANP00000019803	ENSOANP00000026778	Uncharacterized protein.	DHR-2 domain-containing protein; Belongs to the DOCK family.	0.927
F7E214_ORNAN	F7G762_ORNAN	ENSOANP00000019803	ENSOANP00000014480	Uncharacterized protein.	Uncharacterized protein.	0.518
F7EB29_ORNAN	F7BU59_ORNAN	ENSOANP00000026778	ENSOANP00000023980	DHR-2 domain-containing protein; Belongs to the DOCK family.	Uncharacterized protein.	0.618
F7EB29_ORNAN	F7E214_ORNAN	ENSOANP00000026778	ENSOANP00000019803	DHR-2 domain-containing protein; Belongs to the DOCK family.	Uncharacterized protein.	0.927
F7EB29_ORNAN	F7G762_ORNAN	ENSOANP00000026778	ENSOANP00000014480	DHR-2 domain-containing protein; Belongs to the DOCK family.	Uncharacterized protein.	0.717