72 items (Ornithorhynchus anatinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6QH54_ORNAN	Uncharacterized protein. (258 aa)
	COX7A2	Cytochrome c oxidase subunit 7A2. (81 aa)
	NCOR2	Nuclear receptor corepressor 2. (2532 aa)
	F7D3P6_ORNAN	DUF1518 domain-containing protein. (553 aa)
	F6YD21_ORNAN	PAS domain-containing protein. (626 aa)
	F6TNE0_ORNAN	Uncharacterized protein. (279 aa)
	F6RVT0_ORNAN	Uncharacterized protein. (80 aa)
	HMOX2	Heme oxygenase 2. (315 aa)
	COX4I1	Cytochrome c oxidase subunit 4I1. (169 aa)
	COX5B	Cytochrome c oxidase subunit 5B. (98 aa)
	COX19	Cytochrome c oxidase assembly factor COX19. (92 aa)
	F7ECC3_ORNAN	PAS domain-containing protein. (1176 aa)
	HELZ2	RNB domain-containing protein. (1963 aa)
	F7C4X2_ORNAN	VWFD domain-containing protein. (975 aa)
	CREBBP	CREB binding protein. (2473 aa)
	SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (378 aa)
	PPARA	Peroxisome proliferator activated receptor alpha. (409 aa)
	COX5A	Cytochrome c oxidase subunit 5A. (141 aa)
	COX6B1	Cytochrome c oxidase subunit 6B1. (86 aa)
	F7BCD0_ORNAN	Uncharacterized protein. (222 aa)
	F7EHE8_ORNAN	Nucleic_acid_bd domain-containing protein. (951 aa)
	F7CKD2_ORNAN	Uncharacterized protein. (72 aa)
	COX7A2L	Cytochrome c oxidase subunit 7A2 like. (131 aa)
	HBZ	Hemoglobin subunit zeta; Belongs to the globin family. (142 aa)
	LOC100077443	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	DESI1	Desumoylating isopeptidase 1. (167 aa)
	TBL1XR1	Uncharacterized protein. (388 aa)
	F6TS63_ORNAN	Uncharacterized protein. (230 aa)
	F6TRR2_ORNAN	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (455 aa)
	TBL1X	Uncharacterized protein. (527 aa)
	COX20	Cytochrome c oxidase assembly factor COX20. (106 aa)
	DESI2	Desumoylating isopeptidase 2. (199 aa)
	FABP1	Fatty acid binding protein 1. (127 aa)
	SIN3A	SIN3 transcription regulator family member A. (1277 aa)
	BLVRA	Biliverdin reductase A; Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor; Belongs to the Gfo/Idh/MocA family. Biliverdin reductase subfamily. (295 aa)
	HMOX1	Heme oxygenase 1. (290 aa)
	NCOR1	Nuclear receptor corepressor 1. (2463 aa)
	HBA	Hemoglobin subunit alpha; Involved in oxygen transport from the lung to the various peripheral tissues. (121 aa)
	SIN3B	SIN3 transcription regulator family member B. (1137 aa)
	CHD9	Chromodomain helicase DNA binding protein 9. (2901 aa)
	F7CXT1_ORNAN	Uncharacterized protein. (767 aa)
	F7EPH9_ORNAN	Uncharacterized protein. (159 aa)
	SPPL3	Signal peptide peptidase like 3. (347 aa)
	COX3	Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (261 aa)
	COX2	Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (230 aa)
	COX1	Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (513 aa)
	F7ECQ4_ORNAN	WD_REPEATS_REGION domain-containing protein. (137 aa)
	F6R0K4_ORNAN	Uncharacterized protein. (75 aa)
	CLCC1	Uncharacterized protein. (113 aa)
	TGS1	Trimethylguanosine synthase 1. (790 aa)
	LRPPRC	Uncharacterized protein. (275 aa)
	F6X4C6_ORNAN	SURF1-like protein; Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. Belongs to the SURF1 family. (127 aa)
	K7E6I7_ORNAN	NAD(P)-bd_dom domain-containing protein. (97 aa)
	CARM1	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (136 aa)
	K7E6Q2_ORNAN	DUF862 domain-containing protein. (103 aa)
	K7E7M0_ORNAN	Uncharacterized protein. (98 aa)
	K7E8A8_ORNAN	Uncharacterized protein. (127 aa)
	K7E9B4_ORNAN	SURF1-like protein; Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. Belongs to the SURF1 family. (189 aa)
	NPVF	Uncharacterized protein. (210 aa)
	K7EA10_ORNAN	Uncharacterized protein. (154 aa)
	HM13	Uncharacterized protein. (57 aa)
	BLVRB	Uncharacterized protein. (76 aa)
	K7ECZ1_ORNAN	Uncharacterized protein. (92 aa)
	K7EDK1_ORNAN	BHLH domain-containing protein. (101 aa)
	NCOR2-2	SANT domain-containing protein. (109 aa)
	K7EEB3_ORNAN	Uncharacterized protein. (55 aa)
	K7EFP3_ORNAN	GLOBIN domain-containing protein; Belongs to the globin family. (145 aa)
	K7EGQ5_ORNAN	CARM1 domain-containing protein. (154 aa)
	K7EH38_ORNAN	BRK domain-containing protein. (139 aa)
	K7EI39_ORNAN	Uncharacterized protein. (142 aa)
	K7EI68_ORNAN	Uncharacterized protein. (264 aa)
	K7EI71_ORNAN	SURF1-like protein; Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. Belongs to the SURF1 family. (122 aa)

Your Current Organism:

Ornithorhynchus anatinus

NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BLVRA	BLVRB	ENSOANP00000016952	ENSOANP00000031010	Biliverdin reductase A; Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor; Belongs to the Gfo/Idh/MocA family. Biliverdin reductase subfamily.	Uncharacterized protein.	0.757
BLVRA	HMOX1	ENSOANP00000016952	ENSOANP00000017223	Biliverdin reductase A; Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor; Belongs to the Gfo/Idh/MocA family. Biliverdin reductase subfamily.	Heme oxygenase 1.	0.655
BLVRA	HMOX2	ENSOANP00000016952	ENSOANP00000003830	Biliverdin reductase A; Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor; Belongs to the Gfo/Idh/MocA family. Biliverdin reductase subfamily.	Heme oxygenase 2.	0.648
BLVRA	K7E6I7_ORNAN	ENSOANP00000016952	ENSOANP00000029144	Biliverdin reductase A; Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor; Belongs to the Gfo/Idh/MocA family. Biliverdin reductase subfamily.	NAD(P)-bd_dom domain-containing protein.	0.757
BLVRB	BLVRA	ENSOANP00000031010	ENSOANP00000016952	Uncharacterized protein.	Biliverdin reductase A; Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor; Belongs to the Gfo/Idh/MocA family. Biliverdin reductase subfamily.	0.757
BLVRB	COX1	ENSOANP00000031010	ENSOANP00000024995	Uncharacterized protein.	Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]	0.735
BLVRB	COX2	ENSOANP00000031010	ENSOANP00000024994	Uncharacterized protein.	Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]	0.729
BLVRB	COX3	ENSOANP00000031010	ENSOANP00000024991	Uncharacterized protein.	Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]	0.720
BLVRB	COX4I1	ENSOANP00000031010	ENSOANP00000005940	Uncharacterized protein.	Cytochrome c oxidase subunit 4I1.	0.621
BLVRB	COX5A	ENSOANP00000031010	ENSOANP00000010425	Uncharacterized protein.	Cytochrome c oxidase subunit 5A.	0.696
BLVRB	COX5B	ENSOANP00000031010	ENSOANP00000006082	Uncharacterized protein.	Cytochrome c oxidase subunit 5B.	0.628
BLVRB	COX6B1	ENSOANP00000031010	ENSOANP00000010523	Uncharacterized protein.	Cytochrome c oxidase subunit 6B1.	0.549
BLVRB	COX7A2L	ENSOANP00000031010	ENSOANP00000014318	Uncharacterized protein.	Cytochrome c oxidase subunit 7A2 like.	0.468
BLVRB	F6RVT0_ORNAN	ENSOANP00000031010	ENSOANP00000003787	Uncharacterized protein.	Uncharacterized protein.	0.464
BLVRB	F7EPH9_ORNAN	ENSOANP00000031010	ENSOANP00000023241	Uncharacterized protein.	Uncharacterized protein.	0.629
BLVRB	HMOX1	ENSOANP00000031010	ENSOANP00000017223	Uncharacterized protein.	Heme oxygenase 1.	0.933
CARM1	CREBBP	ENSOANP00000029152	ENSOANP00000009307	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	CREB binding protein.	0.730
CARM1	F6TS63_ORNAN	ENSOANP00000029152	ENSOANP00000015142	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Uncharacterized protein.	0.947
CARM1	F6YD21_ORNAN	ENSOANP00000029152	ENSOANP00000003097	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	PAS domain-containing protein.	0.452
CARM1	F7D3P6_ORNAN	ENSOANP00000029152	ENSOANP00000002214	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	DUF1518 domain-containing protein.	0.452