STRINGSTRING
SMAD2 SMAD2 BRCA1 BRCA1 PIK3CA PIK3CA KRAS KRAS F6QE10_ORNAN F6QE10_ORNAN SMAD4 SMAD4 F7EH46_ORNAN F7EH46_ORNAN TGFB3 TGFB3 GAPDH GAPDH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD2Mothers against decapentaplegic homolog. (467 aa)
BRCA1Uncharacterized protein. (208 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
KRASKRAS proto-oncogene, GTPase. (188 aa)
F6QE10_ORNANTransforming growth factor beta; Belongs to the TGF-beta family. (416 aa)
SMAD4Mothers against decapentaplegic homolog. (556 aa)
F7EH46_ORNANAlkaline phosphatase. (172 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (295 aa)
GAPDHGp_dh_C domain-containing protein. (161 aa)
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
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