STRINGSTRING
FGF17 FGF17 FGF14 FGF14 FGF6 FGF6 FGF1 FGF1 FGF18 FGF18 FGF22 FGF22 FGF13 FGF13 CCN2 CCN2 PXDN PXDN FGF7 FGF7 TWIST1 TWIST1 FGF9 FGF9 LOC100093029 LOC100093029 FGF19 FGF19 FGF4 FGF4 FGF3 FGF3 PXDNL PXDNL GDNF GDNF GAPDH GAPDH FGF5 FGF5 VIM VIM COL1A1 COL1A1 FGF10 FGF10 GLUL GLUL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (169 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (195 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
FGF18Uncharacterized protein; Belongs to the heparin-binding growth factors family. (98 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (96 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
CCN2Cellular communication network factor 2. (349 aa)
PXDNPeroxidasin. (1365 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (99 aa)
TWIST1Twist family bHLH transcription factor 1. (156 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LOC100093029Glutamine synthetase. (383 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (87 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (202 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
PXDNLVWFC domain-containing protein. (876 aa)
GDNFGlial cell derived neurotrophic factor. (218 aa)
GAPDHGp_dh_C domain-containing protein. (161 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (152 aa)
VIMIF rod domain-containing protein; Belongs to the intermediate filament family. (305 aa)
COL1A1Uncharacterized protein. (1219 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (99 aa)
GLULGlutamine synthetase. (373 aa)
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
Server load: low (28%) [HD]