(14 nodes) (2019) Defective homologous recombination DNA repair as therapeutic target in advanced chordoma. network (Ornithorhynchus anatinus)

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Predicted Interactions

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Your Input:
	LYST	Lysosomal trafficking regulator. (3735 aa)
	PDGFRA	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (872 aa)
	RAD51C	RAD51 paralog C. (458 aa)
	CHEK2	Checkpoint kinase 2. (553 aa)
	POLE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1770 aa)
	EGFR	Receptor protein-tyrosine kinase. (1215 aa)
	TP53	P53 domain-containing protein. (87 aa)
	SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1. (348 aa)
	TBXT	T-box transcription factor T. (436 aa)
	BRCA2	Tower domain-containing protein. (3459 aa)
	FANCG	Uncharacterized protein. (304 aa)
	POLE-2	DNA polymerase epsilon catalytic subunit A isoform X1. (127 aa)
	BRCA1	Uncharacterized protein. (208 aa)
	ARID1A	Uncharacterized protein. (249 aa)

Your Current Organism:

Ornithorhynchus anatinus

NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARID1A	SMARCB1	ENSOANP00000031715	ENSOANP00000019292	Uncharacterized protein.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1.	0.985
ARID1A	TP53	ENSOANP00000031715	ENSOANP00000018980	Uncharacterized protein.	P53 domain-containing protein.	0.485
BRCA1	BRCA2	ENSOANP00000031186	ENSOANP00000024376	Uncharacterized protein.	Tower domain-containing protein.	0.992
BRCA1	CHEK2	ENSOANP00000031186	ENSOANP00000014054	Uncharacterized protein.	Checkpoint kinase 2.	0.921
BRCA1	EGFR	ENSOANP00000031186	ENSOANP00000016946	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.433
BRCA1	POLE	ENSOANP00000031186	ENSOANP00000016841	Uncharacterized protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.622
BRCA1	POLE-2	ENSOANP00000031186	ENSOANP00000029905	Uncharacterized protein.	DNA polymerase epsilon catalytic subunit A isoform X1.	0.621
BRCA1	RAD51C	ENSOANP00000031186	ENSOANP00000013505	Uncharacterized protein.	RAD51 paralog C.	0.833
BRCA1	TP53	ENSOANP00000031186	ENSOANP00000018980	Uncharacterized protein.	P53 domain-containing protein.	0.904
BRCA2	BRCA1	ENSOANP00000024376	ENSOANP00000031186	Tower domain-containing protein.	Uncharacterized protein.	0.992
BRCA2	CHEK2	ENSOANP00000024376	ENSOANP00000014054	Tower domain-containing protein.	Checkpoint kinase 2.	0.763
BRCA2	FANCG	ENSOANP00000024376	ENSOANP00000029792	Tower domain-containing protein.	Uncharacterized protein.	0.540
BRCA2	POLE	ENSOANP00000024376	ENSOANP00000016841	Tower domain-containing protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.571
BRCA2	POLE-2	ENSOANP00000024376	ENSOANP00000029905	Tower domain-containing protein.	DNA polymerase epsilon catalytic subunit A isoform X1.	0.571
BRCA2	RAD51C	ENSOANP00000024376	ENSOANP00000013505	Tower domain-containing protein.	RAD51 paralog C.	0.991
BRCA2	TP53	ENSOANP00000024376	ENSOANP00000018980	Tower domain-containing protein.	P53 domain-containing protein.	0.824
CHEK2	BRCA1	ENSOANP00000014054	ENSOANP00000031186	Checkpoint kinase 2.	Uncharacterized protein.	0.921
CHEK2	BRCA2	ENSOANP00000014054	ENSOANP00000024376	Checkpoint kinase 2.	Tower domain-containing protein.	0.763
CHEK2	POLE	ENSOANP00000014054	ENSOANP00000016841	Checkpoint kinase 2.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.595
CHEK2	POLE-2	ENSOANP00000014054	ENSOANP00000029905	Checkpoint kinase 2.	DNA polymerase epsilon catalytic subunit A isoform X1.	0.595