STRINGSTRING
ADCY7 ADCY7 PIK3R2 PIK3R2 MAPK14 MAPK14 RPS6KB1 RPS6KB1 F6STU0_ORNAN F6STU0_ORNAN NOTCH1 NOTCH1 GPER1 GPER1 CCDC170 CCDC170 PIK3R1 PIK3R1 FOS FOS IGF1 IGF1 ADCY9 ADCY9 PIK3R3 PIK3R3 MDM2 MDM2 MAPK10 MAPK10 PRKACA PRKACA SHC2 SHC2 PTK2 PTK2 ADCY8 ADCY8 JAG1 JAG1 ABCB11 ABCB11 ESR2 ESR2 GNAS GNAS MAP2K2 MAP2K2 MAPK13 MAPK13 MAPK9 MAPK9 AKT3 AKT3 EGFR EGFR MMP2 MMP2 NOTCH2 NOTCH2 ADCY2 ADCY2 TP53 TP53 NCOA3 NCOA3 MAPK8 MAPK8 DLL4 DLL4 NCOR1 NCOR1 BRAF BRAF PIK3CA PIK3CA SOS2 SOS2 PRKACB PRKACB PIK3CB PIK3CB SOS1 SOS1 ADCY4 ADCY4 RB1 RB1 RAF1-2 RAF1-2 E2F2 E2F2 ADCY6 ADCY6 MTOR MTOR CARM1 CARM1 RPS6KB2 RPS6KB2 K7E8A8_ORNAN K7E8A8_ORNAN MED1 MED1 ADCY3 ADCY3 IGF1R IGF1R MAPK1 MAPK1 DLL1 DLL1 ADCY1 ADCY1 AKT1 AKT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADCY7Guanylate cyclase domain-containing protein. (322 aa)
PIK3R2Uncharacterized protein. (724 aa)
MAPK14Protein kinase domain-containing protein. (126 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (478 aa)
F6STU0_ORNANANK_REP_REGION domain-containing protein. (106 aa)
NOTCH1Notch receptor 1. (2492 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (376 aa)
CCDC170Coiled-coil domain containing 170. (693 aa)
PIK3R1SH2 domain-containing protein. (230 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (336 aa)
IGF1Insulin like growth factor 1. (153 aa)
ADCY9Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (376 aa)
PIK3R3Uncharacterized protein. (462 aa)
MDM2MDM2 proto-oncogene. (438 aa)
MAPK10Mitogen-activated protein kinase. (408 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha. (312 aa)
SHC2Uncharacterized protein. (553 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1142 aa)
ADCY8Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (953 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
ABCB11ATP binding cassette subfamily B member 11. (1326 aa)
ESR2Estrogen receptor 2. (554 aa)
GNASUncharacterized protein. (335 aa)
MAP2K2Protein kinase domain-containing protein. (252 aa)
MAPK13Mitogen-activated protein kinase. (376 aa)
MAPK9Mitogen-activated protein kinase. (429 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (477 aa)
EGFRReceptor protein-tyrosine kinase. (1215 aa)
MMP2Matrix metallopeptidase 2. (656 aa)
NOTCH2Uncharacterized protein. (1873 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1020 aa)
TP53P53 domain-containing protein. (87 aa)
NCOA3Nuclear receptor coactivator. (1447 aa)
MAPK8Protein kinase domain-containing protein. (338 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (419 aa)
NCOR1Nuclear receptor corepressor 1. (2463 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (702 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1333 aa)
PRKACBUncharacterized protein. (243 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1034 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1214 aa)
ADCY4Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (92 aa)
RB1Uncharacterized protein. (725 aa)
RAF1-2Protein kinase domain-containing protein. (141 aa)
E2F2E2F_TDP domain-containing protein. (176 aa)
ADCY6Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (574 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2191 aa)
CARM1Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (136 aa)
RPS6KB2Protein kinase domain-containing protein. (140 aa)
K7E8A8_ORNANUncharacterized protein. (127 aa)
MED1Uncharacterized protein. (83 aa)
ADCY3Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (123 aa)
IGF1RRecep_L_domain domain-containing protein. (214 aa)
MAPK1Protein kinase domain-containing protein. (150 aa)
DLL1EGF-like domain-containing protein. (52 aa)
ADCY1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (118 aa)
AKT1Uncharacterized protein. (230 aa)
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
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