STRINGSTRING
FGFR2 FGFR2 KAT6A KAT6A SKIL SKIL APC APC FZD10 FZD10 PIK3R2 PIK3R2 LOC100082000 LOC100082000 WNT5A WNT5A PCGF6 PCGF6 GSK3B GSK3B MAPK14 MAPK14 ID2 ID2 FGFR1 FGFR1 SOX2 SOX2 PIK3R1 PIK3R1 WNT7A WNT7A MYF5 MYF5 FZD2 FZD2 ZFHX3 ZFHX3 HAND1 HAND1 DUSP9 DUSP9 FZD9 FZD9 IGF1 IGF1 BMI1 BMI1 PIK3R3 PIK3R3 ACVR1C ACVR1C ACVR1 ACVR1 FZD3 FZD3 SMAD1 SMAD1 CTNNB1 CTNNB1 LIF LIF TBX3 TBX3 WNT11 WNT11 AXIN2 AXIN2 FZD6 FZD6 MYC MYC SMAD4 SMAD4 ONECUT1 ONECUT1 HOXD1 HOXD1 WNT2 WNT2 FZD4 FZD4 BMPR1A BMPR1A HOXA1 HOXA1 MAP2K2 MAP2K2 WNT4 WNT4 SMAD5 SMAD5 MAPK13 MAPK13 JAK2 JAK2 AKT3 AKT3 WNT5B WNT5B INHBA INHBA ISL1 ISL1 WNT8B WNT8B TCF7 TCF7 LIFR LIFR ID3 ID3 BMPR1B BMPR1B POU5F1 POU5F1 SMARCAD1 SMARCAD1 PIK3CA PIK3CA ZIC3 ZIC3 LHX5 LHX5 PIK3CB PIK3CB HESX1 HESX1 WNT9A WNT9A SMAD9 SMAD9 RAF1-2 RAF1-2 JAK1 JAK1 F6XEC2_ORNAN F6XEC2_ORNAN PCGF2 PCGF2 IL6ST IL6ST ESRRB ESRRB PCGF1 PCGF1 STAT3 STAT3 IGF1R IGF1R TCF3-2 TCF3-2 MAPK1 MAPK1 NODAL NODAL LOC103167928 LOC103167928 K7EE13_ORNAN K7EE13_ORNAN SETDB1 SETDB1 RIF1 RIF1 APC2 APC2 AKT1 AKT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGFR2Receptor protein-tyrosine kinase. (642 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1999 aa)
SKILc-SKI_SMAD_bind domain-containing protein. (574 aa)
APCAPC regulator of WNT signaling pathway. (2844 aa)
FZD10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
PIK3R2Uncharacterized protein. (724 aa)
LOC100082000TGF_BETA_2 domain-containing protein. (369 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (257 aa)
PCGF6Uncharacterized protein. (138 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (247 aa)
MAPK14Protein kinase domain-containing protein. (126 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
FGFR1Fibroblast growth factor receptor. (821 aa)
SOX2SRY-box transcription factor 2. (285 aa)
PIK3R1SH2 domain-containing protein. (230 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (282 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (256 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
ZFHX3Zinc finger homeobox 3. (3701 aa)
HAND1Heart and neural crest derivatives expressed 1. (192 aa)
DUSP9Dual specificity phosphatase 9. (334 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (477 aa)
IGF1Insulin like growth factor 1. (153 aa)
BMI1RING-type domain-containing protein. (326 aa)
PIK3R3Uncharacterized protein. (462 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (494 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (529 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (645 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
CTNNB1Catenin beta 1. (781 aa)
LIFLIF interleukin 6 family cytokine. (201 aa)
TBX3T-box transcription factor 3. (749 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
AXIN2Axin 2. (841 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (601 aa)
MYCBHLH domain-containing protein. (182 aa)
SMAD4Mothers against decapentaplegic homolog. (556 aa)
ONECUT1Homeobox domain-containing protein. (77 aa)
HOXD1Homeobox protein HoxA/B/D1. (110 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). (361 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (507 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
HOXA1Homeobox domain-containing protein. (117 aa)
MAP2K2Protein kinase domain-containing protein. (252 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (233 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
MAPK13Mitogen-activated protein kinase. (376 aa)
JAK2Tyrosine-protein kinase. (948 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (477 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (212 aa)
INHBAInhibin subunit beta A. (429 aa)
ISL1ISL LIM homeobox 1. (349 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
TCF7HMG box domain-containing protein. (173 aa)
LIFRLIF receptor subunit alpha. (923 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (123 aa)
BMPR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (313 aa)
POU5F1Homeobox domain-containing protein. (141 aa)
SMARCAD1Uncharacterized protein. (828 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
ZIC3Uncharacterized protein. (142 aa)
LHX5LIM homeobox 5. (243 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1034 aa)
HESX1HESX homeobox 1. (184 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (182 aa)
SMAD9Mothers against decapentaplegic homolog. (466 aa)
RAF1-2Protein kinase domain-containing protein. (141 aa)
JAK1Protein kinase domain-containing protein. (107 aa)
F6XEC2_ORNANUncharacterized protein. (137 aa)
PCGF2Uncharacterized protein. (68 aa)
IL6STInterleukin 6 signal transducer. (783 aa)
ESRRBNR LBD domain-containing protein. (183 aa)
PCGF1Uncharacterized protein. (94 aa)
STAT3STAT_alpha domain-containing protein. (156 aa)
IGF1RRecep_L_domain domain-containing protein. (214 aa)
TCF3-2Uncharacterized protein. (94 aa)
MAPK1Protein kinase domain-containing protein. (150 aa)
NODALTGF_BETA_2 domain-containing protein. (79 aa)
LOC103167928TGF_BETA_2 domain-containing protein. (168 aa)
K7EE13_ORNANProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (129 aa)
SETDB1Uncharacterized protein. (183 aa)
RIF1Uncharacterized protein. (89 aa)
APC2Uncharacterized protein. (144 aa)
AKT1Uncharacterized protein. (230 aa)
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
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