STRINGSTRING
KCNK3 KCNK3 KCNJ5 KCNJ5 ADCY7 ADCY7 ATP2B3 ATP2B3 ATP1B1 ATP1B1 SCARB1 SCARB1 PLCB2 PLCB2 CALM1 CALM1 ATP2B4 ATP2B4 CAMK2A CAMK2A ATP1B4 ATP1B4 NPPA NPPA DAGLB DAGLB GNA11 GNA11 ITPR1 ITPR1 PRKD3 PRKD3 CREB3L2 CREB3L2 ADCY9 ADCY9 NR4A2 NR4A2 PRKACA PRKACA ATP2B1 ATP2B1 NPR1 NPR1 ORAI1 ORAI1 KCNK9 KCNK9 PRKCA PRKCA ADCY8 ADCY8 PLCB1 PLCB1 ATF2 ATF2 CREB5 CREB5 GNAS GNAS F7EIH6_ORNAN F7EIH6_ORNAN PRKCG PRKCG CREB1 CREB1 PRKCE PRKCE ADCY2 ADCY2 MC2R MC2R ATF1 ATF1 PLCB3 PLCB3 STAR STAR CREB3L3 CREB3L3 CALML4 CALML4 AGT AGT PRKD1 PRKD1 CACNA1D CACNA1D PRKACB PRKACB F7EGI2_ORNAN F7EGI2_ORNAN ADCY4 ADCY4 CAMK4 CAMK4 CAMK1D CAMK1D LOC103165382 LOC103165382 AGTR1 AGTR1 PLCB4 PLCB4 ADCY6 ADCY6 LDLR LDLR DAGLA DAGLA K7E7V9_ORNAN K7E7V9_ORNAN K7E8T1_ORNAN K7E8T1_ORNAN ADCY3 ADCY3 ATP1A3 ATP1A3 K7E974_ORNAN K7E974_ORNAN CACNA1C CACNA1C CACNA1G-2 CACNA1G-2 CACNA1H CACNA1H ITPR2 ITPR2 ATP1A1 ATP1A1 ADCY1 ADCY1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KCNK3Potassium two pore domain channel subfamily K member 3. (291 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (319 aa)
ADCY7Guanylate cyclase domain-containing protein. (322 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1172 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (228 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
PLCB2PH_14 domain-containing protein. (170 aa)
CALM1Uncharacterized protein; Belongs to the calmodulin family. (113 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1216 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (492 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (308 aa)
NPPANatriuretic peptide A. (150 aa)
DAGLBLipase_3 domain-containing protein. (673 aa)
GNA11G protein subunit alpha 11. (198 aa)
ITPR1Uncharacterized protein. (1597 aa)
PRKD3Uncharacterized protein. (729 aa)
CREB3L2Uncharacterized protein. (177 aa)
ADCY9Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (376 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (518 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha. (312 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1176 aa)
NPR1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (282 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (203 aa)
KCNK9Potassium channel subfamily K member. (334 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (597 aa)
ADCY8Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (953 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1096 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (499 aa)
GNASUncharacterized protein. (335 aa)
F7EIH6_ORNANPhosphodiesterase. (473 aa)
PRKCGUncharacterized protein. (304 aa)
CREB1BZIP domain-containing protein. (47 aa)
PRKCEC2 domain-containing protein. (126 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1020 aa)
MC2RMelanocortin 2 receptor. (310 aa)
ATF1Activating transcription factor 1. (206 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1122 aa)
STARSteroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (288 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (352 aa)
CALML4Calmodulin like 4. (191 aa)
AGTSERPIN domain-containing protein; Belongs to the serpin family. (488 aa)
PRKD1Protein kinase D1. (816 aa)
CACNA1DCa_chan_IQ domain-containing protein. (938 aa)
PRKACBUncharacterized protein. (243 aa)
F7EGI2_ORNANCation_ATPase_N domain-containing protein. (130 aa)
ADCY4Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (92 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (434 aa)
CAMK1DCalcium/calmodulin dependent protein kinase ID. (375 aa)
LOC103165382Uncharacterized protein; Belongs to the calmodulin family. (149 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (357 aa)
PLCB4Phosphoinositide phospholipase C. (938 aa)
ADCY6Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (574 aa)
LDLRLow density lipoprotein receptor. (872 aa)
DAGLAUncharacterized protein. (349 aa)
K7E7V9_ORNANCation_ATPase_C domain-containing protein. (122 aa)
K7E8T1_ORNANUncharacterized protein. (112 aa)
ADCY3Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (123 aa)
ATP1A3Uncharacterized protein. (161 aa)
K7E974_ORNAN3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (369 aa)
CACNA1CIon_trans domain-containing protein. (156 aa)
CACNA1G-2Uncharacterized protein. (235 aa)
CACNA1HIon_trans domain-containing protein. (257 aa)
ITPR2Uncharacterized protein. (323 aa)
ATP1A1Cation_ATPase_C domain-containing protein. (91 aa)
ADCY1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (118 aa)
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
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