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| | PSMD1 | Proteasome 26S subunit, non-ATPase 1. (639 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (285 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (449 aa) |
| | VDAC3 | Voltage dependent anion channel 3. (284 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (757 aa) |
| | KLC1 | Uncharacterized protein. (639 aa) |
| | APC | APC regulator of WNT signaling pathway. (2844 aa) |
| | FZD10 | Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (341 aa) |
| | NAE1 | NEDD8 activating enzyme E1 subunit 1. (445 aa) |
| | COX7A2 | Cytochrome c oxidase subunit 7A2. (81 aa) |
| | PIK3R2 | Uncharacterized protein. (724 aa) |
| | GRIN2B | Uncharacterized protein. (554 aa) |
| | F7D2R6_ORNAN | Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (91 aa) |
| | CAPN2 | Calpain 2; Belongs to the peptidase C2 family. (700 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (257 aa) |
| | PLCB2 | PH_14 domain-containing protein. (170 aa) |
| | CASP7 | Uncharacterized protein; Belongs to the peptidase C14A family. (302 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (247 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (215 aa) |
| | CALM1 | Uncharacterized protein; Belongs to the calmodulin family. (113 aa) |
| | NDUFS4 | NADH:ubiquinone oxidoreductase subunit S4. (180 aa) |
| | UQCRC1 | Ubiquinol-cytochrome c reductase core protein 1. (480 aa) |
| | NDUFB10 | NADH:ubiquinone oxidoreductase subunit B10. (175 aa) |
| | ATP5PB | ATP synthase peripheral stalk-membrane subunit b. (250 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (389 aa) |
| | INSR | Recep_L_domain domain-containing protein. (180 aa) |
| | UQCRFS1 | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (202 aa) |
| | NDUFS1 | Uncharacterized protein; Belongs to the complex I 75 kDa subunit family. (400 aa) |
| | F6RVT0_ORNAN | Uncharacterized protein. (80 aa) |
| | ATP5PO | Uncharacterized protein. (211 aa) |
| | CHUK | Protein kinase domain-containing protein. (719 aa) |
| | NDUFA1 | NADH:ubiquinone oxidoreductase subunit A1. (70 aa) |
| | NDUFA10 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (314 aa) |
| | RTN3 | Reticulon. (436 aa) |
| | TUBB6 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (358 aa) |
| | NDUFS5 | Uncharacterized protein. (106 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (440 aa) |
| | UQCRC2 | Ubiquinol-cytochrome c reductase core protein 2. (454 aa) |
| | ATG2A | ATG_C domain-containing protein. (133 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (811 aa) |
| | ADRM1 | Adhesion regulating molecule 1. (407 aa) |
| | PSMA7 | Proteasome subunit alpha type. (222 aa) |
| | COX4I1 | Cytochrome c oxidase subunit 4I1. (169 aa) |
| | ITPR1 | Uncharacterized protein. (1597 aa) |
| | NDUFB1 | Uncharacterized protein. (251 aa) |
| | COX5B | Cytochrome c oxidase subunit 5B. (98 aa) |
| | EIF2AK2 | Uncharacterized protein. (552 aa) |
| | F7A3C5_ORNAN | Uncharacterized protein; Belongs to the peptidase C14A family. (487 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (337 aa) |
| | PSMA5 | Proteasome subunit alpha type. (217 aa) |
| | NDUFA6 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (131 aa) |
| | PSMC1 | Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (367 aa) |
| | PIK3R1 | SH2 domain-containing protein. (230 aa) |
| | GAPDH | Gp_dh_C domain-containing protein. (161 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (282 aa) |
| | NDUFA8 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (156 aa) |
| | ATP2A2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1061 aa) |
| | TUBB2A | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa) |
| | RELA | RHD domain-containing protein. (159 aa) |
| | NDUFA5 | NADH:ubiquinone oxidoreductase subunit A5. (116 aa) |
| | TRAF2 | RING-type domain-containing protein. (258 aa) |
| | NDUFA11 | Uncharacterized protein. (116 aa) |
| | FZD2 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa) |
| | PSMD7 | MPN domain-containing protein. (325 aa) |
| | PPIF | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (205 aa) |
| | NDUFV2 | NADH:ubiquinone oxidoreductase core subunit V2. (225 aa) |
| | FZD9 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (477 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1250 aa) |
| | NOS2 | Nitric oxide synthase; Produces nitric oxide (NO). (1144 aa) |
| | VDAC2 | Voltage dependent anion channel 2. (297 aa) |
| | PIK3R3 | Uncharacterized protein. (462 aa) |
| | LPL | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (482 aa) |
| | KIF5B | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (966 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (408 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (645 aa) |
| | BACE2 | Beta-secretase 2; Belongs to the peptidase A1 family. (410 aa) |
| | COX5A | Cytochrome c oxidase subunit 5A. (141 aa) |
| | ATG2B | Autophagy related 2B. (1797 aa) |
| | NDUFA12 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (198 aa) |
| | PSMA1 | Proteasome subunit alpha type. (267 aa) |
| | PIK3R4 | Phosphoinositide-3-kinase regulatory subunit 4. (1362 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | LRP6 | LDL receptor related protein 6. (1462 aa) |
| | CSF1 | Uncharacterized protein. (537 aa) |
| | DKK1 | Dickkopf WNT signaling pathway inhibitor 1. (260 aa) |
| | ATP5PD | ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (161 aa) |
| | CYBB | Cytochrome b-245 beta chain. (571 aa) |
| | GRIN2A | Glutamate ionotropic receptor NMDA type subunit 2A. (1452 aa) |
| | RB1CC1 | RB1 inducible coiled-coil 1. (1600 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) |
| | NDUFAB1 | Carrier domain-containing protein. (52 aa) |
| | NDUFB3 | NADH:ubiquinone oxidoreductase subunit B3. (96 aa) |
| | TUBA1B | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) |
| | DKK2 | Dickkopf_N domain-containing protein. (186 aa) |
| | WIPI1 | Uncharacterized protein. (166 aa) |
| | NDUFS3 | NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (264 aa) |
| | PSMD12 | Proteasome 26S subunit, non-ATPase 12. (397 aa) |
| | AXIN2 | Axin 2. (841 aa) |
| | FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (601 aa) |
| | NDUFB8 | Uncharacterized protein. (128 aa) |
| | PPP3R1 | Uncharacterized protein. (180 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1096 aa) |
| | ATP5MC3 | ATP synthase membrane subunit c locus 3; Belongs to the ATPase C chain family. (141 aa) |
| | WNT2 | Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). (361 aa) |
| | XBP1 | X-box binding protein 1. (190 aa) |
| | NOX4 | NADPH oxidase 4. (508 aa) |
| | GRM5 | Glutamate metabotropic receptor 5. (1185 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (507 aa) |
| | NDUFV1 | NADH_4Fe-4S domain-containing protein. (73 aa) |
| | COX7A2L | Cytochrome c oxidase subunit 7A2 like. (131 aa) |
| | ADAM10 | ADAM metallopeptidase domain 10. (723 aa) |
| | LOC100077443 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | HSD17B10 | Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (197 aa) |
| | TUBB1 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) |
| | SDHC | Uncharacterized protein. (89 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1228 aa) |
| | RYR3 | Uncharacterized protein. (2798 aa) |
| | MME | Peptidase_M13_N domain-containing protein. (333 aa) |
| | MAP2K2 | Protein kinase domain-containing protein. (252 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (233 aa) |
| | SDHA | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (652 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (429 aa) |
| | PSEN2 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (416 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (477 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2 alpha kinase 3. (1028 aa) |
| | GPR83 | G protein-coupled receptor 83; Belongs to the G-protein coupled receptor 1 family. (396 aa) |
| | WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (212 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (290 aa) |
| | PSMA2 | Proteasome subunit alpha type. (293 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (514 aa) |
| | WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa) |
| | BID | Uncharacterized protein. (138 aa) |
| | RTN4 | Reticulon. (1022 aa) |
| | ATP5MC2 | ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (120 aa) |
| | NDUFA2 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (100 aa) |
| | KIF5C | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (478 aa) |
| | MAPK8 | Protein kinase domain-containing protein. (338 aa) |
| | CSNK2A2 | Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa) |
| | MAPT | Microtubule-associated protein. (192 aa) |
| | SEM1 | Uncharacterized protein. (70 aa) |
| | ULK2 | Unc-51 like autophagy activating kinase 2. (1074 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1122 aa) |
| | SLC25A5 | Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (252 aa) |
| | ATP2A1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (710 aa) |
| | PSMA4 | Proteasome subunit alpha type. (261 aa) |
| | ADAM17 | Uncharacterized protein. (429 aa) |
| | GRIN1 | Uncharacterized protein. (532 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (702 aa) |
| | NDUFB2 | Uncharacterized protein. (127 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | VDAC1 | Voltage dependent anion channel 1. (269 aa) |
| | CALML4 | Calmodulin like 4. (191 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa) |
| | PSMA6 | Proteasome subunit alpha type. (246 aa) |
| | BACE1 | Beta-secretase 1; Belongs to the peptidase A1 family. (498 aa) |
| | CACNA1D | Ca_chan_IQ domain-containing protein. (938 aa) |
| | APOE | Uncharacterized protein. (286 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1034 aa) |
| | ATP2A3 | Cation_ATPase_C domain-containing protein. (224 aa) |
| | F7EPH9_ORNAN | Uncharacterized protein. (159 aa) |
| | ATP5F1A | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (554 aa) |
| | PPID | Peptidylprolyl isomerase D. (369 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (512 aa) |
| | NRBF2 | Nuclear receptor binding factor 2. (287 aa) |
| | CHRNA7 | Neur_chan_memb domain-containing protein. (302 aa) |
| | WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (182 aa) |
| | ATP5F1C | ATP synthase subunit gamma. (298 aa) |
| | LOC103165382 | Uncharacterized protein; Belongs to the calmodulin family. (149 aa) |
| | IDE | Insulin degrading enzyme; Belongs to the peptidase M16 family. (1021 aa) |
| | CYTB | Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa) |
| | ND6 | NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (166 aa) |
| | MT-ND5 | NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (604 aa) |
| | MT-ND4 | NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (460 aa) |
| | ND4L | NADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (98 aa) |
| | MT-ND3 | NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (115 aa) |
| | COX3 | Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (261 aa) |
| | ATP6 | ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (226 aa) |
| | ATP8 | ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (69 aa) |
| | COX2 | Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (230 aa) |
| | COX1 | Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (513 aa) |
| | MT-ND2 | NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (347 aa) |
| | ND1 | NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (318 aa) |
| | ATP5F1E | ATP synthase F1 subunit epsilon. (51 aa) |
| | NDUFB9 | NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (165 aa) |
| | RAF1-2 | Protein kinase domain-containing protein. (141 aa) |
| | DKK4 | Dickkopf_N domain-containing protein. (219 aa) |
| | F7GE03_ORNAN | Uncharacterized protein. (294 aa) |
| | PSMC3 | Prot_ATP_ID_OB domain-containing protein. (136 aa) |
| | PLCB4 | Phosphoinositide phospholipase C. (938 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2191 aa) |
| | PSMD9 | PDZ domain-containing protein. (174 aa) |
| | CAPN1 | EF-hand domain-containing protein. (74 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) |
| | NDUFB5 | Uncharacterized protein. (119 aa) |
| | NOS1 | Flavodoxin-like domain-containing protein. (301 aa) |
| | NFKB1 | RHD domain-containing protein. (267 aa) |
| | IL6 | Uncharacterized protein. (154 aa) |
| | KIF5A | Uncharacterized protein. (122 aa) |
| | K7E8T1_ORNAN | Uncharacterized protein. (112 aa) |
| | NDUFB6 | Uncharacterized protein. (121 aa) |
| | PSMB7 | Uncharacterized protein. (57 aa) |
| | CACNA1C | Ion_trans domain-containing protein. (156 aa) |
| | ERN1-2 | Uncharacterized protein. (67 aa) |
| | APBB1 | Uncharacterized protein. (69 aa) |
| | TUBA8 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (486 aa) |
| | MAPK1 | Protein kinase domain-containing protein. (150 aa) |
| | FAS | Death domain-containing protein. (114 aa) |
| | GRIN2D | ANF_receptor domain-containing protein. (300 aa) |
| | PSMD2 | RPN1_RPN2_N domain-containing protein. (145 aa) |
| | K7EE13_ORNAN | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (129 aa) |
| | ATG13-2 | Uncharacterized protein. (80 aa) |
| | K7EEY1_ORNAN | Tubulin_C domain-containing protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (242 aa) |
| | K7EFK4_ORNAN | Tubulin domain-containing protein. (111 aa) |
| | ITPR2 | Uncharacterized protein. (323 aa) |
| | ULK1 | Uncharacterized protein. (95 aa) |
| | PSMB1 | Uncharacterized protein. (72 aa) |
| | PSMD3 | Rpn3_C domain-containing protein. (96 aa) |
| | APC2 | Uncharacterized protein. (144 aa) |
| | AKT1 | Uncharacterized protein. (230 aa) |
| | UQCRQ | Ubiquinol-cytochrome c reductase complex III subunit VII. (82 aa) |
