STRINGSTRING
PSMD1 PSMD1 CASP3 CASP3 SOD2 SOD2 VDAC3 VDAC3 KLC1 KLC1 DNAL1 DNAL1 COX7A2 COX7A2 GRIN2B GRIN2B F7D2R6_ORNAN F7D2R6_ORNAN PLCB2 PLCB2 PSMB4 PSMB4 NDUFS4 NDUFS4 UQCRC1 UQCRC1 NDUFB10 NDUFB10 ATP5PB ATP5PB PSMD6 PSMD6 UQCRFS1 UQCRFS1 DCTN4 DCTN4 NDUFS1 NDUFS1 F6RVT0_ORNAN F6RVT0_ORNAN ATP5PO ATP5PO NDUFA1 NDUFA1 NDUFA10 NDUFA10 TUBB6 TUBB6 NDUFS5 NDUFS5 DNAH1 DNAH1 UQCRC2 UQCRC2 POLR2A POLR2A ATG2A ATG2A PIK3C3 PIK3C3 ADRM1 ADRM1 PSMA7 PSMA7 HDAC2 HDAC2 COX4I1 COX4I1 ITPR1 ITPR1 GPX7 GPX7 NDUFB1 NDUFB1 COX5B COX5B F7A3C5_ORNAN F7A3C5_ORNAN GRIA3 GRIA3 PSMC4 PSMC4 PSMA5 PSMA5 NDUFA6 NDUFA6 PSMC1 PSMC1 DNAH12 DNAH12 PSMB5 PSMB5 LOC100076559 LOC100076559 LOC100076636 LOC100076636 DNAH6 DNAH6 NDUFA8 NDUFA8 TUBB2A TUBB2A NDUFA5 NDUFA5 DCTN6 DCTN6 TRAF2 TRAF2 NDUFA11 NDUFA11 CREB3L2 CREB3L2 PSMD7 PSMD7 GRIA1 GRIA1 PPIF PPIF NDUFV2 NDUFV2 APAF1 APAF1 F6XXW7_ORNAN F6XXW7_ORNAN POLR2G POLR2G VDAC2 VDAC2 KIF5B KIF5B PSMD14 PSMD14 MAPK10 MAPK10 COX5A COX5A ATG2B ATG2B NDUFA12 NDUFA12 PSMA1 PSMA1 PPARGC1A PPARGC1A PIK3R4 PIK3R4 GPX2 GPX2 ATP5PD ATP5PD RB1CC1 RB1CC1 SLC1A2 SLC1A2 IFT57 IFT57 NDUFAB1 NDUFAB1 NDUFB3 NDUFB3 DCTN5 DCTN5 TUBA1B TUBA1B WIPI1 WIPI1 NDUFS3 NDUFS3 PSMD12 PSMD12 ACTR1A ACTR1A NDUFB8 NDUFB8 PLCB1 PLCB1 CLTC CLTC ATP5MC3 ATP5MC3 GRM5 GRM5 NDUFV1 NDUFV1 COX7A2L COX7A2L LOC100077443 LOC100077443 CREB5 CREB5 TUBB1 TUBB1 SDHC SDHC POLR2C POLR2C MAP3K5 MAP3K5 CREB1 CREB1 SDHA SDHA MAPK9 MAPK9 POLR2H POLR2H GRIA4 GRIA4 PSMA2 PSMA2 POLR2B POLR2B ATP5MC2 ATP5MC2 DLG4 DLG4 DNAH5 DNAH5 NDUFA2 NDUFA2 DNAH11 DNAH11 KIF5C KIF5C ACTR10 ACTR10 TP53 TP53 MAPK8 MAPK8 SEM1 SEM1 GPX8 GPX8 ULK2 ULK2 PLCB3 PLCB3 TBP TBP SLC1A3 SLC1A3 SLC25A5 SLC25A5 BDNF BDNF TBPL1 TBPL1 DNAH7 DNAH7 DNAH8 DNAH8 POLR2D POLR2D PSMA4 PSMA4 CREB3L3 CREB3L3 GRIN1 GRIN1 NDUFB2 NDUFB2 PSMB2 PSMB2 VDAC1 VDAC1 PSMA6 PSMA6 DNAH3 DNAH3 GPX6 GPX6 POLR2F POLR2F F7EPH9_ORNAN F7EPH9_ORNAN ATP5F1A ATP5F1A PSMC2 PSMC2 NRBF2 NRBF2 CLTB CLTB ATP5F1C ATP5F1C GRIA2 GRIA2 CYTB CYTB ND6 ND6 MT-ND5 MT-ND5 MT-ND4 MT-ND4 ND4L ND4L MT-ND3 MT-ND3 COX3 COX3 ATP6 ATP6 ATP8 ATP8 COX2 COX2 COX1 COX1 MT-ND2 MT-ND2 ND1 ND1 ATP5F1E ATP5F1E NDUFB9 NDUFB9 PSMC3 PSMC3 POLR2J POLR2J PLCB4 PLCB4 MTOR MTOR PSMD9 PSMD9 EP300 EP300 NDUFB5 NDUFB5 PPARG PPARG TBPL2 TBPL2 KIF5A KIF5A K7E8T1_ORNAN K7E8T1_ORNAN NDUFB6 NDUFB6 PSMB7 PSMB7 DCTN1 DCTN1 ERN1-2 ERN1-2 TUBA8 TUBA8 DNAH2 DNAH2 HTT HTT DNAH14 DNAH14 PSMD2 PSMD2 HDAC1-2 HDAC1-2 ATG13-2 ATG13-2 K7EEY1_ORNAN K7EEY1_ORNAN K7EFK4_ORNAN K7EFK4_ORNAN DNAH17 DNAH17 ULK1 ULK1 PSMB1 PSMB1 PSMD3 PSMD3 UQCRQ UQCRQ AP2A1 AP2A1 MAP3K10 MAP3K10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMD1Proteasome 26S subunit, non-ATPase 1. (639 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (285 aa)
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (221 aa)
VDAC3Voltage dependent anion channel 3. (284 aa)
KLC1Uncharacterized protein. (639 aa)
DNAL1Dynein axonemal light chain 1. (192 aa)
COX7A2Cytochrome c oxidase subunit 7A2. (81 aa)
GRIN2BUncharacterized protein. (554 aa)
F7D2R6_ORNANCytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (91 aa)
PLCB2PH_14 domain-containing protein. (170 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (215 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (180 aa)
UQCRC1Ubiquinol-cytochrome c reductase core protein 1. (480 aa)
NDUFB10NADH:ubiquinone oxidoreductase subunit B10. (175 aa)
ATP5PBATP synthase peripheral stalk-membrane subunit b. (250 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (202 aa)
DCTN4Dynactin subunit 4. (471 aa)
NDUFS1Uncharacterized protein; Belongs to the complex I 75 kDa subunit family. (400 aa)
F6RVT0_ORNANUncharacterized protein. (80 aa)
ATP5POUncharacterized protein. (211 aa)
NDUFA1NADH:ubiquinone oxidoreductase subunit A1. (70 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (314 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (358 aa)
NDUFS5Uncharacterized protein. (106 aa)
DNAH1DHC_N2 domain-containing protein. (1026 aa)
UQCRC2Ubiquinol-cytochrome c reductase core protein 2. (454 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (952 aa)
ATG2AATG_C domain-containing protein. (133 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (811 aa)
ADRM1Adhesion regulating molecule 1. (407 aa)
PSMA7Proteasome subunit alpha type. (222 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (430 aa)
COX4I1Cytochrome c oxidase subunit 4I1. (169 aa)
ITPR1Uncharacterized protein. (1597 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (141 aa)
NDUFB1Uncharacterized protein. (251 aa)
COX5BCytochrome c oxidase subunit 5B. (98 aa)
F7A3C5_ORNANUncharacterized protein; Belongs to the peptidase C14A family. (487 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (890 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (337 aa)
PSMA5Proteasome subunit alpha type. (217 aa)
NDUFA6NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (131 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (367 aa)
DNAH12Uncharacterized protein. (1076 aa)
PSMB5Proteasome subunit beta. (263 aa)
LOC100076559Uncharacterized protein. (264 aa)
LOC100076636Uncharacterized protein. (263 aa)
DNAH6Uncharacterized protein. (1127 aa)
NDUFA8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (156 aa)
TUBB2ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
NDUFA5NADH:ubiquinone oxidoreductase subunit A5. (116 aa)
DCTN6Dynactin subunit 6. (184 aa)
TRAF2RING-type domain-containing protein. (258 aa)
NDUFA11Uncharacterized protein. (116 aa)
CREB3L2Uncharacterized protein. (177 aa)
PSMD7MPN domain-containing protein. (325 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (900 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (205 aa)
NDUFV2NADH:ubiquinone oxidoreductase core subunit V2. (225 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1250 aa)
F6XXW7_ORNANDHC_N1 domain-containing protein. (331 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
VDAC2Voltage dependent anion channel 2. (297 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (966 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
MAPK10Mitogen-activated protein kinase. (408 aa)
COX5ACytochrome c oxidase subunit 5A. (141 aa)
ATG2BAutophagy related 2B. (1797 aa)
NDUFA12NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (198 aa)
PSMA1Proteasome subunit alpha type. (267 aa)
PPARGC1APPARG coactivator 1 alpha. (795 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1362 aa)
GPX2Glutathione peroxidase; Belongs to the glutathione peroxidase family. (141 aa)
ATP5PDATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (161 aa)
RB1CC1RB1 inducible coiled-coil 1. (1600 aa)
SLC1A2Amino acid transporter. (576 aa)
IFT57Intraflagellar transport 57. (415 aa)
NDUFAB1Carrier domain-containing protein. (52 aa)
NDUFB3NADH:ubiquinone oxidoreductase subunit B3. (96 aa)
DCTN5Dynactin subunit 5. (182 aa)
TUBA1BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
WIPI1Uncharacterized protein. (166 aa)
NDUFS3NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (264 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (397 aa)
ACTR1AActin related protein 1A; Belongs to the actin family. (365 aa)
NDUFB8Uncharacterized protein. (128 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1096 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1685 aa)
ATP5MC3ATP synthase membrane subunit c locus 3; Belongs to the ATPase C chain family. (141 aa)
GRM5Glutamate metabotropic receptor 5. (1185 aa)
NDUFV1NADH_4Fe-4S domain-containing protein. (73 aa)
COX7A2LCytochrome c oxidase subunit 7A2 like. (131 aa)
LOC100077443Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (499 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
SDHCUncharacterized protein. (89 aa)
POLR2CRNA polymerase II subunit C. (230 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1228 aa)
CREB1BZIP domain-containing protein. (47 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (652 aa)
MAPK9Mitogen-activated protein kinase. (429 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
GRIA4Uncharacterized protein. (679 aa)
PSMA2Proteasome subunit alpha type. (293 aa)
POLR2BUncharacterized protein; Belongs to the RNA polymerase beta chain family. (839 aa)
ATP5MC2ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (120 aa)
DLG4Uncharacterized protein. (188 aa)
DNAH5Dynein axonemal heavy chain 5. (4623 aa)
NDUFA2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (100 aa)
DNAH11Uncharacterized protein. (2005 aa)
KIF5CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (478 aa)
ACTR10Actin related protein 10; Belongs to the actin family. (395 aa)
TP53P53 domain-containing protein. (87 aa)
MAPK8Protein kinase domain-containing protein. (338 aa)
SEM1Uncharacterized protein. (70 aa)
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (210 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1074 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1122 aa)
TBPTATA-box binding protein. (328 aa)
SLC1A3Amino acid transporter. (257 aa)
SLC25A5Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (252 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (85 aa)
TBPL1TATA-box binding protein like 1. (183 aa)
DNAH7Uncharacterized protein. (1067 aa)
DNAH8Dynein axonemal heavy chain 8. (4713 aa)
POLR2DRNA polymerase II subunit D. (118 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (352 aa)
GRIN1Uncharacterized protein. (532 aa)
NDUFB2Uncharacterized protein. (127 aa)
PSMB2Proteasome subunit beta. (201 aa)
VDAC1Voltage dependent anion channel 1. (269 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
DNAH3Dynein axonemal heavy chain 3. (4074 aa)
GPX6Glutathione peroxidase; Belongs to the glutathione peroxidase family. (217 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
F7EPH9_ORNANUncharacterized protein. (159 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (554 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (512 aa)
NRBF2Nuclear receptor binding factor 2. (287 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (185 aa)
ATP5F1CATP synthase subunit gamma. (298 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa)
ND6NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (166 aa)
MT-ND5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (604 aa)
MT-ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (460 aa)
ND4LNADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (98 aa)
MT-ND3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (115 aa)
COX3Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (261 aa)
ATP6ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (226 aa)
ATP8ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (69 aa)
COX2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (230 aa)
COX1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (513 aa)
MT-ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (347 aa)
ND1NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (318 aa)
ATP5F1EATP synthase F1 subunit epsilon. (51 aa)
NDUFB9NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (165 aa)
PSMC3Prot_ATP_ID_OB domain-containing protein. (136 aa)
POLR2JRNA polymerase II subunit J. (117 aa)
PLCB4Phosphoinositide phospholipase C. (938 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2191 aa)
PSMD9PDZ domain-containing protein. (174 aa)
EP300E1A binding protein p300. (2421 aa)
NDUFB5Uncharacterized protein. (119 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (217 aa)
TBPL2Transcription initiation factor TFIID TATA-box-binding protein. (115 aa)
KIF5AUncharacterized protein. (122 aa)
K7E8T1_ORNANUncharacterized protein. (112 aa)
NDUFB6Uncharacterized protein. (121 aa)
PSMB7Uncharacterized protein. (57 aa)
DCTN1Uncharacterized protein. (140 aa)
ERN1-2Uncharacterized protein. (67 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (486 aa)
DNAH2DHC_N2 domain-containing protein. (328 aa)
HTTUncharacterized protein. (261 aa)
DNAH14DHC_N2 domain-containing protein. (132 aa)
PSMD2RPN1_RPN2_N domain-containing protein. (145 aa)
HDAC1-2Hist_deacetyl domain-containing protein. (200 aa)
ATG13-2Uncharacterized protein. (80 aa)
K7EEY1_ORNANTubulin_C domain-containing protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (242 aa)
K7EFK4_ORNANTubulin domain-containing protein. (111 aa)
DNAH17Uncharacterized protein. (267 aa)
ULK1Uncharacterized protein. (95 aa)
PSMB1Uncharacterized protein. (72 aa)
PSMD3Rpn3_C domain-containing protein. (96 aa)
UQCRQUbiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
AP2A1Adaptin_N domain-containing protein. (174 aa)
MAP3K10Uncharacterized protein. (138 aa)
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
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