STRINGSTRING
rsmA rsmA AEV31130.1 AEV31130.1 truA truA mnmA mnmA rho rho AEV31202.1 AEV31202.1 AEV31222.1 AEV31222.1 AEV31236.1 AEV31236.1 AEV31262.1 AEV31262.1 AEV31266.1 AEV31266.1 thrS thrS AEV31338.1 AEV31338.1 trmD trmD AEV31427.1 AEV31427.1 fmt fmt rnz rnz AEV31535.1 AEV31535.1 mnmE mnmE AEV31564.1 AEV31564.1 AEV31629.1 AEV31629.1 AEV31666.1 AEV31666.1 argS argS tsaD tsaD AEV31738.1 AEV31738.1 AEV31779.1 AEV31779.1 AEV31823.1 AEV31823.1 AEV31858.1 AEV31858.1 hisS hisS AEV31870.1 AEV31870.1 AEV31877.1 AEV31877.1 AEV31953.1 AEV31953.1 AEV31966.1 AEV31966.1 AEV31985.1 AEV31985.1 rlmF rlmF AEV32028.1 AEV32028.1 AEV32039.1 AEV32039.1 valS valS rimO rimO AEV32160.1 AEV32160.1 priA priA AEV32169.1 AEV32169.1 AEV32178.1 AEV32178.1 AEV32206.1 AEV32206.1 rny rny AEV32314.1 AEV32314.1 AEV32341.1 AEV32341.1 AEV32355.1 AEV32355.1 AEV32375.1 AEV32375.1 rlmH rlmH rpoC rpoC rpoB rpoB nusG nusG AEV32503.1 AEV32503.1 pnp pnp AEV32509.1 AEV32509.1 AEV32516.1 AEV32516.1 AEV32609.1 AEV32609.1 AEV32639.1 AEV32639.1 AEV32732.1 AEV32732.1 rsmG rsmG tgt tgt AEV32741.1 AEV32741.1 tilS tilS AEV32808.1 AEV32808.1 AEV32813.1 AEV32813.1 rnhB rnhB alaS alaS AEV32871.1 AEV32871.1 AEV32877.1 AEV32877.1 queG queG nusA nusA truB truB tyrS tyrS AEV32953.1 AEV32953.1 AEV32985.1 AEV32985.1 AEV33022.1 AEV33022.1 rbfA rbfA tadA tadA aspS aspS AEV33111.1 AEV33111.1 AEV33122.1 AEV33122.1 AEV33127.1 AEV33127.1 AEV33143.1 AEV33143.1 trmB trmB rsmI rsmI AEV33154.1 AEV33154.1 AEV33159.1 AEV33159.1 asnS asnS AEV33179.1 AEV33179.1 lysS lysS AEV33247.1 AEV33247.1 rnr rnr gltX gltX ybeY ybeY mnmG mnmG pheS pheS rnc rnc AEV33331.1 AEV33331.1 AEV33365.1 AEV33365.1 ileS ileS AEV33547.1 AEV33547.1 AEV33563.1 AEV33563.1 glyQS glyQS rnpA rnpA dnaG dnaG rlmN rlmN leuS leuS AEV33729.1 AEV33729.1 metG metG miaB miaB rsmH rsmH dtd dtd AEV33942.1 AEV33942.1 AEV33953.1 AEV33953.1 pheT pheT rpoA rpoA AEV34081.1 AEV34081.1 cysS cysS proS proS AEV34097.1 AEV34097.1 AEV34121.1 AEV34121.1 rimM rimM AEV34178.1 AEV34178.1 AEV34323.1 AEV34323.1 AEV34348.1 AEV34348.1 miaA miaA AEV34466.1 AEV34466.1 AEV34481.1 AEV34481.1 AEV34488.1 AEV34488.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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rsmADimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (254 aa)
AEV31130.1PFAM: Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family. (411 aa)
truAPseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (248 aa)
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (393 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (561 aa)
AEV31202.1PFAM: Plasmid encoded toxin Txe; TIGRFAM: toxin-antitoxin system, toxin component, Txe/YoeB family. (86 aa)
AEV31222.1MiaB-like tRNA modifying enzyme; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: MiaB-like tRNA modifying enzyme; radical SAM methylthiotransferase, MiaB/RimO family. (446 aa)
AEV31236.1PFAM: Plasmid encoded toxin Txe; TIGRFAM: toxin-antitoxin system, toxin component, Txe/YoeB family. (84 aa)
AEV31262.1Export-related chaperone CsaA; PFAM: Putative tRNA binding domain; TIGRFAM: export-related chaperone CsaA. (108 aa)
AEV31266.1PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region. (156 aa)
thrSthreonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (645 aa)
AEV31338.1PFAM: Protein of unknown function DUF88. (251 aa)
trmDtRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (225 aa)
AEV31427.1PFAM: tRNA (Uracil-5-)-methyltransferase; TRAM domain; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (479 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (312 aa)
rnzRibonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (316 aa)
AEV31535.1Hypothetical protein. (150 aa)
mnmEtRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (464 aa)
AEV31564.1Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA; PFAM: tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE). (195 aa)
AEV31629.1Hypothetical protein. (110 aa)
AEV31666.1PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily. (198 aa)
argSarginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase. (594 aa)
tsaDPutative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (340 aa)
AEV31738.1RNA methyltransferase, RsmE family; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (231 aa)
AEV31779.1PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily. (195 aa)
AEV31823.1Hypothetical protein. (205 aa)
AEV31858.1N6-adenine-specific methylase; PFAM: Conserved hypothetical protein 95. (387 aa)
hisSPFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase. (463 aa)
AEV31870.1PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; Belongs to the SUA5 family. (207 aa)
AEV31877.1Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (313 aa)
AEV31953.1Putative methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases. (240 aa)
AEV31966.1tRNA/rRNA cytosine-C5-methylase; PFAM: NOL1/NOP2/sun family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (404 aa)
AEV31985.1Hypothetical protein. (267 aa)
rlmFPutative SAM-dependent methyltransferase; Specifically methylates the adenine in position 1618 of 23S rRNA. (328 aa)
AEV32028.1Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA; PFAM: tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE). (193 aa)
AEV32039.1rRNA methylase, putative, group 3; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (251 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (874 aa)
rimORibosomal protein S12 methylthiotransferase RimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (433 aa)
AEV32160.1PFAM: Putative RNA methylase family UPF0020; THUMP domain; manually curated; Belongs to the methyltransferase superfamily. (388 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (822 aa)
AEV32169.1PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase, RluA family. (227 aa)
AEV32178.1PFAM: tRNA pseudouridine synthase; TIGRFAM: pseudouridylate synthase I; manually curated. (267 aa)
AEV32206.1RNAse H-fold protein YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (138 aa)
rnyConserved hypothetical protein YmdA/YtgF; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family. (512 aa)
AEV32314.1Hypothetical protein. (950 aa)
AEV32341.1PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily. (178 aa)
AEV32355.1Putative nucleic acid-binding protein, contains PIN domain. (139 aa)
AEV32375.1RNA methyltransferase, RsmD family; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family. (185 aa)
rlmHHypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (157 aa)
rpoCDNA-directed RNA polymerase, beta' subunit, predominant form; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1439 aa)
rpoBDNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1274 aa)
nusGTranscription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. (183 aa)
AEV32503.1PFAM: SpoU rRNA Methylase family. (240 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (707 aa)
AEV32509.1RNA polymerase sigma factor, sigma-70 family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (287 aa)
AEV32516.1PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; manually curated; Belongs to the sigma-70 factor family. ECF subfamily. (198 aa)
AEV32609.1PFAM: ECF sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family. (189 aa)
AEV32639.1PFAM: Seryl-tRNA synthetase N-terminal domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: seryl-tRNA synthetase. (423 aa)
AEV32732.1Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (349 aa)
rsmG16S rRNA (guanine(527)-N(7))-methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (208 aa)
tgttRNA-guanine transglycosylase, queuosine-34-forming; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of [...] (376 aa)
AEV32741.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (497 aa)
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (453 aa)
AEV32808.1PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily. (197 aa)
AEV32813.1ATPase, YjeE family; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family. (142 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (201 aa)
alaSalanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (873 aa)
AEV32871.1RRM domain-containing RNA-binding protein; PFAM: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain). (111 aa)
AEV32877.1PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ. (229 aa)
queGIron-sulfur cluster binding protein, putative; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (310 aa)
nusATranscription termination factor NusA; Participates in both transcription termination and antitermination. (411 aa)
truBtRNA pseudouridine 55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (238 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (431 aa)
AEV32953.1PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily. (183 aa)
AEV32985.1Putative sulfurtransferase; PFAM: Rhodanese-like domain; Belongs to the UPF0176 family. (348 aa)
AEV33022.1Putative TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (331 aa)
rbfARibosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (119 aa)
tadACytosine/adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (148 aa)
aspSaspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (585 aa)
AEV33111.1TIGR00255 family protein; PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732); TIGRFAM: TIGR00255 family protein. (289 aa)
AEV33122.1Putative rRNA methylase SpoU family; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. (155 aa)
AEV33127.1PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa)
AEV33143.1PFAM: Plasmid encoded toxin Txe; TIGRFAM: toxin-antitoxin system, toxin component, Txe/YoeB family. (85 aa)
trmBtRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (223 aa)
rsmIPutative S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (224 aa)
AEV33154.1Hypothetical protein. (421 aa)
AEV33159.1PFAM: tRNA synthetases class I (W and Y); TIGRFAM: tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (323 aa)
asnSPFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: asparaginyl-tRNA synthetase. (476 aa)
AEV33179.1PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54, DNA binding domain; Sigma-54 factor, core binding domain; TIGRFAM: RNA polymerase sigma-54 factor; manually curated. (483 aa)
lysSlysyl-tRNA synthetase (class II); PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial; Belongs to the class-II aminoacyl-tRNA synthetase family. (574 aa)
AEV33247.1PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily. (187 aa)
rnrRibonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (715 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (510 aa)
ybeYMetalloprotein, YbeY/UPF0054 family; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (142 aa)
mnmGGlucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (623 aa)
pheSphenylalanyl-tRNA synthetase alpha subunit; PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (339 aa)
rncRibonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (244 aa)
AEV33331.1Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (151 aa)
AEV33365.1PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily. (186 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1135 aa)
AEV33547.1Putative HD superfamily hydrolase; PFAM: HD domain. (216 aa)
AEV33563.1PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily. (206 aa)
glyQSglycyl-tRNA synthetase, dimeric type; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (511 aa)
rnpARibonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (124 aa)
dnaGDNA primase, catalytic core; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. (657 aa)
rlmN23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (352 aa)
leuSPFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family; Belongs to the class-I aminoacyl-tRNA synthetase family. (929 aa)
AEV33729.1PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family. (281 aa)
metGProtein containing C-terminal region/beta chain of methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (678 aa)
miaBtRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (480 aa)
rsmHS-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (304 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (150 aa)
AEV33942.1PFAM: SpoU rRNA Methylase family. (175 aa)
AEV33953.1Ribonuclease, Rne/Rng family; PFAM: Ribonuclease E/G family; S1 RNA binding domain; TIGRFAM: ribonuclease, Rne/Rng family. (515 aa)
pheTphenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (808 aa)
rpoADNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (330 aa)
AEV34081.1Hypothetical protein. (141 aa)
cysSPFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (493 aa)
proSprolyl-tRNA synthetase, family I; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (491 aa)
AEV34097.1PFAM: Protein of unknown function (DUF752). (222 aa)
AEV34121.1Putative O-methyltransferase; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). (234 aa)
rimM16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (176 aa)
AEV34178.1Hypothetical protein. (951 aa)
AEV34323.1TIGRFAM: methyltransferase, FkbM family. (276 aa)
AEV34348.1Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (317 aa)
miaAtRNA isopentenyltransferase MiaA; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (303 aa)
AEV34466.1Putative domain HDIG-containing protein; PFAM: HD domain; Poly A polymerase head domain; TIGRFAM: uncharacterized domain HDIG; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (469 aa)
AEV34481.1Dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis; PFAM: ThiF family. (375 aa)
AEV34488.1DNA-directed RNA polymerase specialized sigma subunit, sigma24; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily. (167 aa)
Your Current Organism:
Owenweeksia hongkongensis
NCBI taxonomy Id: 926562
Other names: Cryomorphaceae bacterium UST20020801, O. hongkongensis DSM 17368, Owenweeksia hongkongensis DSM 17368, Owenweeksia hongkongensis UST20020801
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