STRINGSTRING
AKF04262.1 AKF04262.1 AKF04696.1 AKF04696.1 AKF04928.1 AKF04928.1 AKF05259.1 AKF05259.1 AKF05543.1 AKF05543.1 AKF05675.1 AKF05675.1 AKF05683.1 AKF05683.1 AKF05819.1 AKF05819.1 glsA glsA AKF06250.1 AKF06250.1 AKF06529.1 AKF06529.1 mdh mdh sucC sucC sucD sucD pheA pheA glyA glyA fumC fumC AKF07573.1 AKF07573.1 AKF07598.1 AKF07598.1 AKF07969.1 AKF07969.1 gcvT gcvT gcvH gcvH gcvPA gcvPA AKF08054.1 AKF08054.1 AKF08055.1 AKF08055.1 AKF08179.1 AKF08179.1 AKF08180.1 AKF08180.1 AKF08181.1 AKF08181.1 AKF08437.1 AKF08437.1 AKF08438.1 AKF08438.1 AKF08439.1 AKF08439.1 pckA pckA AKF08616.1 AKF08616.1 AKF08959.1 AKF08959.1 AKF08960.1 AKF08960.1 AKF09160.1 AKF09160.1 AKF09161.1 AKF09161.1 AKF09446.1 AKF09446.1 AKF10688.1 AKF10688.1 aceK aceK glsA-2 glsA-2 murI murI AKF11066.1 AKF11066.1 AKF11114.1 AKF11114.1 AKF11453.1 AKF11453.1 AKF11506.1 AKF11506.1 AKF11542.1 AKF11542.1 AKF11640.1 AKF11640.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKF04262.1Aminomethyltransferase; Belongs to the GcvT family. (351 aa)
AKF04696.1Asparagine synthetase. (642 aa)
AKF04928.1Aspartate aminotransferase. (447 aa)
AKF05259.1Delta-1-pyrroline-5-carboxylate dehydrogenase. (538 aa)
AKF05543.1Succinate dehydrogenase cytochrome b subunit. (225 aa)
AKF05675.1Glutamine synthetase type I. (471 aa)
AKF05683.1Isoaspartyl aminopeptidase. (290 aa)
AKF05819.1Hypothetical protein. (421 aa)
glsAGlutaminase; Belongs to the glutaminase family. (310 aa)
AKF06250.1Aconitate hydratase. (1063 aa)
AKF06529.1Isocitrate dehydrogenase. (418 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (312 aa)
sucCSuccinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (392 aa)
sucDSuccinyl-CoA ligase [ADP-forming] alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa)
pheAChorismate mutase I. (375 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (466 aa)
AKF07573.1Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (554 aa)
AKF07598.1NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (411 aa)
AKF07969.1Aspartate aminotransferase. (487 aa)
gcvTAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (374 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa)
gcvPAGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (437 aa)
AKF08054.1Chorismate mutase I. (397 aa)
AKF08055.1NAD-dependent malic enzyme. (579 aa)
AKF08179.1Lactam utilization protein LamB; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (229 aa)
AKF08180.1Allophanate hydrolase 2 subunit 1. (195 aa)
AKF08181.1Allophanate hydrolase 2 subunit 2. (283 aa)
AKF08437.1Succinate dehydrogenase cytochrome b subunit. (239 aa)
AKF08438.1Succinate dehydrogenase flavoprotein subunit. (647 aa)
AKF08439.1Succinate dehydrogenase iron-sulfur protein. (264 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (528 aa)
AKF08616.1N-formylglutamate deformylase. (272 aa)
AKF08959.1Glutamate synthase [NADPH] large chain. (1527 aa)
AKF08960.1Glutamate synthase [NADPH] small chain. (483 aa)
AKF09160.1Citrate synthase (si); Belongs to the citrate synthase family. (352 aa)
AKF09161.1Citrate synthase (si). (426 aa)
AKF09446.1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (1542 aa)
AKF10688.1Aspartate aminotransferase. (400 aa)
aceKIsocitrate dehydrogenase phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (574 aa)
glsA-2Glutaminase; Belongs to the glutaminase family. (384 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (278 aa)
AKF11066.1Aspartate ammonia-lyase. (505 aa)
AKF11114.1L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (302 aa)
AKF11453.1NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (421 aa)
AKF11506.1Aspartate aminotransferase. (436 aa)
AKF11542.1Glycine dehydrogenase. (464 aa)
AKF11640.1NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (356 aa)
Your Current Organism:
Sandaracinus amylolyticus
NCBI taxonomy Id: 927083
Other names: DSM 53668, NCCB 100362, S. amylolyticus, Sandaracinus amylolyticus Mohr et al. 2012, Sorangiineae bacterium NOSO 4, strain NOSO-4
Server load: low (20%) [HD]