STRINGSTRING
coaD coaD AKF05076.1 AKF05076.1 AKF05397.1 AKF05397.1 AKF05952.1 AKF05952.1 AKF05966.1 AKF05966.1 AKF06395.1 AKF06395.1 AKF06890.1 AKF06890.1 AKF07103.1 AKF07103.1 coaD-2 coaD-2 ilvE ilvE AKF07457.1 AKF07457.1 ilvC ilvC AKF08062.1 AKF08062.1 AKF08063.1 AKF08063.1 ilvD ilvD panD panD AKF08918.1 AKF08918.1 coaX coaX coaE coaE panC panC panB panB
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (163 aa)
AKF05076.1Acetolactate synthase large subunit; Belongs to the TPP enzyme family. (543 aa)
AKF05397.1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (472 aa)
AKF05952.1Acetolactate synthase large subunit; Belongs to the TPP enzyme family. (545 aa)
AKF05966.1Acetolactate synthase large subunit; Belongs to the TPP enzyme family. (557 aa)
AKF06395.1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (815 aa)
AKF06890.1D-alanine aminotransferase. (289 aa)
AKF07103.1Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (397 aa)
coaD-2Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (168 aa)
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (302 aa)
AKF07457.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (328 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (336 aa)
AKF08062.1Acetolactate synthase small subunit. (196 aa)
AKF08063.1Acetolactate synthase large subunit. (583 aa)
ilvDDihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (565 aa)
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (138 aa)
AKF08918.1Branched-chain amino acid aminotransferase. (349 aa)
coaXPantothenate kinase type III, CoaX-like protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (254 aa)
coaEDephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (205 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (287 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (323 aa)
Your Current Organism:
Sandaracinus amylolyticus
NCBI taxonomy Id: 927083
Other names: DSM 53668, NCCB 100362, S. amylolyticus, Sandaracinus amylolyticus Mohr et al. 2012, Sorangiineae bacterium NOSO 4, strain NOSO-4
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