STRINGSTRING
AKF04559.1 AKF04559.1 AKF04621.1 AKF04621.1 AKF04928.1 AKF04928.1 AKF05076.1 AKF05076.1 AKF05196.1 AKF05196.1 argA argA AKF05819.1 AKF05819.1 AKF05952.1 AKF05952.1 argC argC AKF05966.1 AKF05966.1 AKF06250.1 AKF06250.1 AKF06434.1 AKF06434.1 AKF06529.1 AKF06529.1 AKF06890.1 AKF06890.1 AKF06911.1 AKF06911.1 asd asd argJ argJ ilvE ilvE AKF07797.1 AKF07797.1 AKF07969.1 AKF07969.1 leuB leuB AKF08057.1 AKF08057.1 leuD leuD leuC leuC leuA leuA ilvC ilvC AKF08062.1 AKF08062.1 AKF08063.1 AKF08063.1 ilvD ilvD AKF08918.1 AKF08918.1 AKF09160.1 AKF09160.1 AKF09161.1 AKF09161.1 argD argD argB argB AKF10688.1 AKF10688.1 AKF11506.1 AKF11506.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKF04559.13-isopropylmalate dehydrogenase. (353 aa)
AKF04621.1Citrate synthase (si); Belongs to the citrate synthase family. (428 aa)
AKF04928.1Aspartate aminotransferase. (447 aa)
AKF05076.1Acetolactate synthase large subunit; Belongs to the TPP enzyme family. (543 aa)
AKF05196.1Acetylornithine deacetylase. (404 aa)
argAN-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. (447 aa)
AKF05819.1Hypothetical protein. (421 aa)
AKF05952.1Acetolactate synthase large subunit; Belongs to the TPP enzyme family. (545 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (349 aa)
AKF05966.1Acetolactate synthase large subunit; Belongs to the TPP enzyme family. (557 aa)
AKF06250.1Aconitate hydratase. (1063 aa)
AKF06434.1Aspartokinase; Belongs to the aspartokinase family. (386 aa)
AKF06529.1Isocitrate dehydrogenase. (418 aa)
AKF06890.1D-alanine aminotransferase. (289 aa)
AKF06911.1Aspartokinase; Belongs to the aspartokinase family. (407 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (330 aa)
argJGlutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (409 aa)
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (302 aa)
AKF07797.13-isopropylmalate dehydratase large subunit. (655 aa)
AKF07969.1Aspartate aminotransferase. (487 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (363 aa)
AKF08057.1(R)-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (535 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (200 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (480 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (535 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (336 aa)
AKF08062.1Acetolactate synthase small subunit. (196 aa)
AKF08063.1Acetolactate synthase large subunit. (583 aa)
ilvDDihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (565 aa)
AKF08918.1Branched-chain amino acid aminotransferase. (349 aa)
AKF09160.1Citrate synthase (si); Belongs to the citrate synthase family. (352 aa)
AKF09161.1Citrate synthase (si). (426 aa)
argDAcetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (404 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (290 aa)
AKF10688.1Aspartate aminotransferase. (400 aa)
AKF11506.1Aspartate aminotransferase. (436 aa)
Your Current Organism:
Sandaracinus amylolyticus
NCBI taxonomy Id: 927083
Other names: DSM 53668, NCCB 100362, S. amylolyticus, Sandaracinus amylolyticus Mohr et al. 2012, Sorangiineae bacterium NOSO 4, strain NOSO-4
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