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| | AFD05190.1 | Enoyl-(acyl-carrier-protein) reductase (NADH). (272 aa) |
| | fabV | Putative paraquat-inducible protein B; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (396 aa) |
| | AFD05219.1 | PFAM: Glycosyl hydrolase family 3 C terminal domain; Glycosyl hydrolase family 3 N terminal domain. (760 aa) |
| | AFD05220.1 | Conserved repeat protein; PFAM: Glycosyl hydrolase family 3 C terminal domain; Glycosyl hydrolase family 3 N terminal domain. (739 aa) |
| | AFD05258.1 | Glycosidase; PFAM: Alpha amylase, catalytic domain. (555 aa) |
| | AFD05271.1 | PFAM: Glycosyl hydrolase family 3 C terminal domain; Glycosyl hydrolase family 3 N terminal domain; Belongs to the glycosyl hydrolase 3 family. (771 aa) |
| | AFD05281.1 | PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. (418 aa) |
| | ribBA | GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (403 aa) |
| | AFD05386.1 | Gluconolactonase; PFAM: SMP-30/Gluconolaconase/LRE-like region. (295 aa) |
| | gpsA | PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (336 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa) |
| | AFD05432.1 | 3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (271 aa) |
| | AFD05451.1 | PFAM: Glycosyl hydrolase family 3 C terminal domain; Glycosyl hydrolase family 3 N terminal domain. (772 aa) |
| | AFD05455.1 | PFAM: Glycosyl hydrolase family 3 C terminal domain; Glycosyl hydrolase family 3 N terminal domain; Belongs to the glycosyl hydrolase 3 family. (780 aa) |
| | AFD05457.1 | PFAM: Glycosyl hydrolase family 3 C terminal domain; Glycosyl hydrolase family 3 N terminal domain; Belongs to the glycosyl hydrolase 3 family. (742 aa) |
| | AFD05460.1 | Isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (410 aa) |
| | purH | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain. (508 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (191 aa) |
| | AFD05509.1 | PFAM: Carbohydrate phosphorylase. (552 aa) |
| | metXA | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (340 aa) |
| | AFD05517.1 | OAH/OAS sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme. (441 aa) |
| | AFD05569.1 | PFAM: Glycosyl hydrolases family 31; Belongs to the glycosyl hydrolase 31 family. (823 aa) |
| | glgB | Alpha-1,4-glucan:alpha-1,4-glucan 6-glycosyltransferase; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (669 aa) |
| | AFD05608.1 | PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (326 aa) |
| | mdh | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (312 aa) |
| | miaA | tRNA isopentenyltransferase MiaA; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (307 aa) |
| | AFD05666.1 | Transketolase, alpha subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (317 aa) |
| | AFD05667.1 | Transketolase, beta subunit; PFAM: Transketolase, thiamine diphosphate binding domain. (285 aa) |
| | AFD05670.1 | PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. (464 aa) |
| | AFD05681.1 | Putative 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; Belongs to the UbiA prenyltransferase family. (283 aa) |
| | menG | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (243 aa) |
| | AFD05691.1 | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (246 aa) |
| | AFD05771.1 | PFAM: Glutamine amidotransferases class-II. (633 aa) |
| | AFD05813.1 | Riboflavin synthase, alpha subunit; PFAM: Lumazine binding domain. (194 aa) |
| | AFD05821.1 | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme. (351 aa) |
| | AFD05831.1 | Threonine aldolase; PFAM: Beta-eliminating lyase. (358 aa) |
| | AFD05846.1 | Glycerol-3-phosphate dehydrogenase; PFAM: FAD dependent oxidoreductase. (519 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (258 aa) |
| | hisI | PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; In the N-terminal section; belongs to the PRA-CH family. (195 aa) |
| | hisF | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (374 aa) |
| | hisA | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: Histidine biosynthesis protein. (249 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (208 aa) |
| | hisB | Histidinol-phosphatase; PFAM: Polynucleotide kinase 3 phosphatase; Imidazoleglycerol-phosphate dehydratase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. (398 aa) |
| | hisC | PFAM: Aminotransferase class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (350 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (453 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (283 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (383 aa) |
| | AFD06093.1 | PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. (508 aa) |
| | AFD06176.1 | PFAM: Trehalase. (527 aa) |
| | AFD06257.1 | Glycosyltransferase; PFAM: Glycogen synthase. (604 aa) |
| | AFD06258.1 | Cysteine synthase; PFAM: CBS domain; Pyridoxal-phosphate dependent enzyme. (451 aa) |
| | AFD06316.1 | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (324 aa) |
| | AFD06360.1 | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (333 aa) |
| | trpF | PFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase; Belongs to the TrpF family. (207 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (398 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (257 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (409 aa) |
| | AFD06395.1 | Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (481 aa) |
| | AFD06398.1 | Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain. (462 aa) |
| | AFD06404.1 | Phosphoribosylaminoimidazole (AIR) synthetase; PFAM: AIR synthase related protein, C-terminal domain. (393 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (751 aa) |
| | fbp | Fructose-1,6-bisphosphatase; PFAM: Fructose-1-6-bisphosphatase. (346 aa) |
| | AFD06459.1 | NADH/NADPH-dependent glutamate synthase small subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase. (485 aa) |
| | AFD06460.1 | PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. (1518 aa) |
| | AFD06520.1 | PFAM: Coproporphyrinogen III oxidase. (298 aa) |
| | AFD06535.1 | acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa) |
| | AFD06542.1 | Hexose kinase, 1-phosphofructokinase family; PFAM: pfkB family carbohydrate kinase; Belongs to the carbohydrate kinase PfkB family. (311 aa) |
| | AFD06546.1 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (796 aa) |
| | AFD06596.1 | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (713 aa) |
| | AFD06687.1 | PFAM: Glycosyl hydrolase family 3 C terminal domain; Glycosyl hydrolase family 3 N terminal domain; Belongs to the glycosyl hydrolase 3 family. (730 aa) |
| | surE | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (245 aa) |
| | ubiX | Polyprenyl p-hydroxybenzoate/phenylacrylic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (189 aa) |
| | AFD06783.1 | PFAM: Inositol monophosphatase family. (262 aa) |
| | AFD06789.1 | PFAM: Lyase; Adenylosuccinate lyase C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (447 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, PurK protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (380 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, PurE protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (177 aa) |
| | AFD06816.1 | PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain. (405 aa) |
| | AFD06818.1 | FAD/FMN-dependent dehydrogenase; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain. (466 aa) |
| | AFD06872.1 | PFAM: Ribulose-phosphate 3 epimerase family; Belongs to the ribulose-phosphate 3-epimerase family. (223 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (355 aa) |
| | AFD06874.1 | Phosphoglycerate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (316 aa) |
| | aroQ | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (138 aa) |
| | AFD06916.1 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (354 aa) |
| | mqnA | Putative periplasmic solute-binding protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (254 aa) |
| | mqnE | Putative menaquinone biosynthesis protein, SCO4494 family; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (398 aa) |
| | AFD06926.1 | Cystathionine beta-lyase/cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme. (370 aa) |
| | AFD06928.1 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme. (460 aa) |
| | purC | Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; PFAM: SAICAR synthetase. (316 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (512 aa) |
| | AFD06942.1 | PFAM: Small subunit of acetolactate synthase; ACT domain. (181 aa) |
| | AFD06943.1 | Acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. (581 aa) |
| | ilvD | PFAM: Dehydratase family; Belongs to the IlvD/Edd family. (559 aa) |
| | ilvE | Branched-chain amino acid aminotransferase, group I; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (295 aa) |
| | ilvA | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (417 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (385 aa) |
| | AFD06952.1 | PFAM: Amino acid kinase family; Belongs to the aspartokinase family. (437 aa) |
| | AFD06971.1 | Mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase. (362 aa) |
| | AFD06981.1 | Citrate synthase I, hexameric type; PFAM: Citrate synthase; Belongs to the citrate synthase family. (428 aa) |
| | miaA-2 | tRNA isopentenyltransferase MiaA; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (308 aa) |
| | AFD07047.1 | uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Belongs to the precorrin methyltransferase family. (242 aa) |
| | AFD07067.1 | Menaquinone biosynthesis decarboxylase, SCO4490 family; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Belongs to the UbiD family. (636 aa) |
| | AFD07083.1 | PFAM: Amino acid kinase family; Belongs to the aspartokinase family. (424 aa) |
| | AFD07111.1 | UDP-forming alpha,alpha-trehalose-phosphate synthase; PFAM: Trehalose-phosphatase; Glycosyltransferase family 20. (733 aa) |
| | AFD07116.1 | PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. (388 aa) |
| | AFD07120.1 | Arginine deiminase; PFAM: Amidinotransferase. (516 aa) |
| | AFD07129.1 | PFAM: Prokaryotic diacylglycerol kinase. (119 aa) |
| | AFD07145.1 | PFAM: Aminotransferase class I and II. (398 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (221 aa) |
| | AFD07154.1 | PFAM: Acyltransferase. (261 aa) |
| | tal | Fructose-6-phosphate aldolase, TalC/MipB family; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (221 aa) |
| | AFD07290.1 | PFAM: Homoserine dehydrogenase, NAD binding domain; Homoserine dehydrogenase. (413 aa) |
| | AFD07301.1 | CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (235 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (83 aa) |
| | AFD07322.1 | uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases. (260 aa) |
| | AFD07329.1 | Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (415 aa) |
| | AFD07330.1 | Sulfate adenylyltransferase, small subunit; PFAM: Phosphoadenosine phosphosulfate reductase family. (296 aa) |
| | ispE | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (267 aa) |
| | AFD07341.1 | Isopropylmalate/homocitrate/citramalate synthase; PFAM: HMGL-like. (292 aa) |
| | AFD07346.1 | Glycosidase; PFAM: Alpha amylase, catalytic domain. (469 aa) |
| | AFD07353.1 | DhnA-type fructose-1,6-bisphosphate aldolase-like enzyme; PFAM: DeoC/LacD family aldolase. (351 aa) |
| | AFD07367.1 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (363 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (282 aa) |
| | AFD07371.1 | PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I. (459 aa) |
| | AFD07385.1 | PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (366 aa) |
| | AFD07394.1 | PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. (376 aa) |
| | plsY | Acyl-phosphate glycerol 3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (213 aa) |
| | gpmI | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (515 aa) |
| | guaB | Inosine-5''-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (490 aa) |
| | AFD07504.1 | Menaquinone biosynthesis protein, SCO4550 family; PFAM: Radical SAM superfamily. (373 aa) |
| | AFD07628.1 | PFAM: Glycoside hydrolase 97. (663 aa) |
| | AFD07631.1 | PFAM: Proline dehydrogenase. (403 aa) |
| | AFD07632.1 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (356 aa) |
| | AFD07633.1 | PFAM: Prephenate dehydratase. (275 aa) |
| | AFD07634.1 | 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; PFAM: Chorismate mutase type II; DAHP synthetase I family. (367 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (429 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (357 aa) |
| | AFD07645.1 | Transcriptional regulator/sugar kinase; PFAM: ROK family. (288 aa) |
| | AFD07667.1 | PFAM: Aminotransferase class I and II; manually curated. (410 aa) |
| | AFD07700.1 | 5'-nucleotidase/2',3'-cyclic phosphodiesterase-like hydrolase; PFAM: Calcineurin-like phosphoesterase; Belongs to the 5'-nucleotidase family. (305 aa) |
| | AFD07708.1 | Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain. (469 aa) |
| | AFD07752.1 | 3-carboxymuconate cyclase; PFAM: 3-carboxy-cis,cis-muconate lactonizing enzyme. (376 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (291 aa) |
| | pgk | PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (395 aa) |
| | AFD07782.1 | PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (361 aa) |
| | AFD07788.1 | PFAM: Glycosyl hydrolase family 3 C terminal domain; Glycosyl hydrolase family 3 N terminal domain; PA14 domain. (897 aa) |
| | pckG | Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (613 aa) |
| | adk | Adenylate kinase family protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (189 aa) |
| | AFD07812.1 | PFAM: Phosphomannose isomerase type I. (326 aa) |
| | AFD07814.1 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (327 aa) |
| | AFD07826.1 | Glycosidase; PFAM: Alpha amylase, catalytic domain. (555 aa) |
| | AFD07830.1 | Putative membrane protein; PFAM: Uncharacterised protein family (UPF0093). (176 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (343 aa) |
| | hemL | Glutamate-1-semialdehyde-2,1-aminomutase; PFAM: Aminotransferase class-III. (453 aa) |
| | AFD07836.1 | PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (322 aa) |
| | AFD07837.1 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (527 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (418 aa) |
| | ispG | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (670 aa) |
| | AFD07858.1 | Serine acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats). (270 aa) |
| | AFD07867.1 | PFAM: Radical SAM superfamily. (274 aa) |
| | surE-2 | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (256 aa) |
| | AFD07897.1 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (633 aa) |
| | AFD07906.1 | PFAM: Prephenate dehydrogenase. (290 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (246 aa) |
| | AFD07965.1 | PFAM: Glycoside hydrolase 97. (667 aa) |
| | AFD07975.1 | Riboflavin kinase/FMN adenylyltransferase; PFAM: Riboflavin kinase; FAD synthetase; Belongs to the ribF family. (310 aa) |
| | AFD07982.1 | Aconitate hydratase; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase). (756 aa) |
| | AFD07991.1 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (271 aa) |
| | pgi | PFAM: Phosphoglucose isomerase; Belongs to the GPI family. (549 aa) |
| | AFD08062.1 | Ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain. (323 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa) |
| | AFD08109.1 | Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase. (537 aa) |
| | AFD08139.1 | 2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (406 aa) |
| | AFD08140.1 | PFAM: Dehydrogenase E1 component; Transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component. (930 aa) |
| | AFD08142.1 | Phosphoglycerate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (320 aa) |
| | AFD08154.1 | acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa) |
| | AFD08213.1 | Glycerol-3-phosphate dehydrogenase; PFAM: FAD dependent oxidoreductase. (523 aa) |
| | AFD08220.1 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1231 aa) |
| | gcvT | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (358 aa) |
| | AFD08242.1 | Phosphoglycerate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (312 aa) |
| | AFD08248.1 | Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; PFAM: Dehydrogenase E1 component; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (673 aa) |
| | AFD08257.1 | PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family. (143 aa) |
| | AFD08259.1 | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (446 aa) |
| | AFD08260.1 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (165 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (312 aa) |
| | AFD08267.1 | PFAM: Asparaginase. (329 aa) |
| | AFD08294.1 | Transcriptional regulator/sugar kinase; PFAM: ROK family. (301 aa) |
| | AFD08301.1 | Phospholipase C, phosphocholine-specific; PFAM: Phosphoesterase family; Domain of unknown function (DUF756); TIGRFAM: phospholipase C, phosphocholine-specific, Pseudomonas-type; Tat (twin-arginine translocation) pathway signal sequence. (852 aa) |
| | AFD08331.1 | PFAM: Uroporphyrinogen-III synthase HemD. (252 aa) |
| | AFD08333.1 | Short-chain dehydrogenase of unknown substrate specificity; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (238 aa) |
| | AFD08338.1 | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (375 aa) |
| | AFD08343.1 | Mg-chelatase subunit ChlI. (497 aa) |
| | AFD08356.1 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (180 aa) |
| | ctaB | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (301 aa) |
| | AFD08368.1 | PFAM: Cytochrome oxidase assembly protein. (357 aa) |
| | AFD08392.1 | PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; L-serine dehydratase, iron-sulfur-dependent, single chain form. (473 aa) |
| | AFD08398.1 | PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (176 aa) |
| | AFD08400.1 | PFAM: O-methyltransferase. (211 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (78 aa) |
| | AFD08413.1 | PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. (475 aa) |
| | AFD08433.1 | Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa) |
| | AFD08439.1 | PFAM: chorismate binding enzyme; Anthranilate synthase component I, N terminal region. (469 aa) |
| | AFD08440.1 | PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. (189 aa) |
| | trpC | PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (264 aa) |
| | AFD08448.1 | PFAM: Aminotransferase class I and II. (419 aa) |
| | AFD08453.1 | Monoamine oxidase; PFAM: Flavin containing amine oxidoreductase. (385 aa) |
| | panD | L-aspartate-alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (148 aa) |
| | panC | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (280 aa) |
| | AFD08506.1 | PFAM: Starch synthase catalytic domain. (273 aa) |
| | AFD08555.1 | PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase. (395 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase, common form; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (328 aa) |
| | AFD08557.1 | PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (411 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (260 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (271 aa) |
| | AFD08561.1 | Acetylornithine deacetylase/succinyldiaminopimelate desuccinylase-like deacylase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain. (353 aa) |
| | argH | PFAM: Lyase; TIGRFAM: argininosuccinate lyase. (443 aa) |
| | AFD08584.1 | Putative NADPH-quinone reductase (modulator of drug activity B); PFAM: Flavodoxin-like fold. (202 aa) |
| | AFD08647.1 | PFAM: Catalase; Catalase-related immune-responsive. (498 aa) |
| | AFD08678.1 | PFAM: Glycosyl hydrolase family 3 C terminal domain; Glycosyl hydrolase family 3 N terminal domain; Belongs to the glycosyl hydrolase 3 family. (769 aa) |
| | AFD08679.1 | PFAM: Glycosyl hydrolase family 3 C terminal domain; Glycosyl hydrolase family 3 N terminal domain; Belongs to the glycosyl hydrolase 3 family. (747 aa) |
| | AFD08682.1 | PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (380 aa) |
| | AFD08690.1 | Short-chain alcohol dehydrogenase; PFAM: short chain dehydrogenase. (265 aa) |
| | pckA | ATP-dependent phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (538 aa) |
| | metK | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (417 aa) |
| | AFD08754.1 | PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases. (243 aa) |
| | AFD08762.1 | Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; PFAM: 2Fe-2S iron-sulfur cluster binding domain; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. (252 aa) |
| | AFD08763.1 | PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit, Bacillus subtilis subgroup. (664 aa) |
| | AFD08764.1 | TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family. (229 aa) |
| | AFD08766.1 | PFAM: Asparaginase; TIGRFAM: L-asparaginases, type II; Belongs to the asparaginase 1 family. (352 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (262 aa) |
| | AFD08895.1 | CDP-diglyceride synthetase; PFAM: Cytidylyltransferase family; Belongs to the CDS family. (271 aa) |
| | psd | Phosphatidylserine decarboxylase precursor-related protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (220 aa) |
| | AFD08901.1 | Putative NADPH-quinone reductase (modulator of drug activity B); PFAM: Flavodoxin-like fold. (192 aa) |
| | AFD08934.1 | Monoamine oxidase; PFAM: Flavin containing amine oxidoreductase. (447 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (504 aa) |
| | AFD08988.1 | PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (347 aa) |
| | purD | Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Belongs to the GARS family. (424 aa) |
| | AFD09033.1 | PFAM: ACT domain; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like. (430 aa) |
| | AFD09064.1 | PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II. (354 aa) |
| | pfkA-2 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (322 aa) |
| | AFD09133.1 | Isopropylmalate/homocitrate/citramalate synthase; PFAM: HMGL-like; Belongs to the alpha-IPM synthase/homocitrate synthase family. (389 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (463 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (198 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (357 aa) |
| | AFD09142.1 | Galactose mutarotase-like enzyme; Converts alpha-aldose to the beta-anomer. (349 aa) |
| | mqnB | Futalosine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). (208 aa) |
| | mqnD | Putative periplasmic solute-binding protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (302 aa) |
| | AFD09174.1 | Hypothetical protein; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1. (144 aa) |
| | pdhA | Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (331 aa) |
| | AFD09209.1 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (541 aa) |
| | AFD09215.1 | PFAM: Aldehyde dehydrogenase family. (514 aa) |
| | AFD09229.1 | Aspartate kinase; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; Amino acid kinase family; ACT domain; TIGRFAM: aspartate kinase. (812 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (308 aa) |
| | AFD09231.1 | Threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase. (438 aa) |
| | fumC | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (466 aa) |
| | AFD09238.1 | PFAM: Shikimate dehydrogenase substrate binding domain; TIGRFAM: shikimate 5-dehydrogenase. (248 aa) |
| | ispF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (160 aa) |
| | AFD09273.1 | PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase. (293 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (229 aa) |
| | AFD09290.1 | Glucose-1-phosphate thymidylyltransferase, short form; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (293 aa) |
| | AFD09291.1 | Putative phosphosugar isomerase; PFAM: Bacterial phospho-glucose isomerase C-terminal region; SIS domain; TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase. (325 aa) |
| | AFD09316.1 | PFAM: NAD dependent epimerase/dehydratase family. (379 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (642 aa) |
| | glyA | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (423 aa) |
| | AFD09326.1 | Cytosine deaminase-like metal-dependent hydrolase; PFAM: Amidohydrolase family. (384 aa) |
| | AFD09327.1 | PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. (166 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa) |
| | ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (164 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa) |
| | AFD09381.1 | PFAM: Asparaginase; TIGRFAM: L-asparaginases, type I. (345 aa) |
| | AFD09388.1 | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (323 aa) |
| | AFD09391.1 | PFAM: Aminotransferase class-III; TIGRFAM: ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (414 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (167 aa) |
| | AFD09408.1 | Oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM superfamily; HemN C-terminal region; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (454 aa) |
| | AFD09430.1 | PFAM: Isocitrate lyase family; TIGRFAM: isocitrate lyase. (427 aa) |
| | AFD09431.1 | PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family. (538 aa) |
| | gcvP | Glycine dehydrogenase, decarboxylating; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (976 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (336 aa) |
| | AFD09464.1 | (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (281 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (339 aa) |
| | AFD09470.1 | dTDP-D-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (354 aa) |
