STRINGSTRING
sucC sucC AHF14062.1 AHF14062.1 AHF14064.1 AHF14064.1 purU purU mdh mdh AHF14480.1 AHF14480.1 AHF14556.1 AHF14556.1 AHF14648.1 AHF14648.1 pdhA pdhA AHF15055.1 AHF15055.1 pckA pckA AHF15214.1 AHF15214.1 AHF15252.1 AHF15252.1 AHF15338.1 AHF15338.1 AHF15665.1 AHF15665.1 sdhA sdhA AHF15668.1 AHF15668.1 AHF15724.1 AHF15724.1 AHF16028.1 AHF16028.1 fumC fumC AHF16437.1 AHF16437.1 AHF16497.1 AHF16497.1 AHF16614.1 AHF16614.1 sucD sucD AHF16872.1 AHF16872.1 mqo mqo
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sucCmalate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (403 aa)
AHF14062.12-oxoglutarate dehydrogenase E1; Derived by automated computational analysis using gene prediction method: Protein Homology. (917 aa)
AHF14064.12-oxoglutarate dehydrogenase E2; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (413 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (277 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (309 aa)
AHF14480.1Succinate-semialdehyde dehdyrogenase; In Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)
AHF14556.1Diapophytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
AHF14648.1Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (329 aa)
pdhAPyruvate dehydrogenase E1 subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (331 aa)
AHF15055.1Type I citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (441 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (534 aa)
AHF15214.1Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (547 aa)
AHF15252.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)
AHF15338.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (795 aa)
AHF15665.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (658 aa)
AHF15668.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
AHF15724.1Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (860 aa)
AHF16028.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (661 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
AHF16437.12-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
AHF16497.12-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (614 aa)
AHF16614.1Malic enzyme; NAD-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; does not decarboxylate oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (775 aa)
sucDsuccinyl-CoA synthetase subsunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (291 aa)
AHF16872.1L-lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
mqoMalate:quinone oxidoreductase; Malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (495 aa)
Your Current Organism:
Niabella soli
NCBI taxonomy Id: 929713
Other names: N. soli DSM 19437, Niabella soli DSM 19437, Niabella soli JS13-8, Niabella soli str. DSM 19437, Niabella soli strain DSM 19437
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