73 items (Bipolaris oryzae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	W6YTQ5_COCMI	Uncharacterized protein. (295 aa)
	W6ZS48_COCMI	Uncharacterized protein. (184 aa)
	W6ZTS4_COCMI	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (144 aa)
	W6ZVU1_COCMI	Uncharacterized protein. (766 aa)
	W6ZWZ8_COCMI	Uncharacterized protein. (1414 aa)
	W6ZX72_COCMI	Uncharacterized protein. (92 aa)
	W7A0W6_COCMI	RING-type domain-containing protein. (775 aa)
	W7A1K6_COCMI	Uncharacterized protein; Belongs to the AAA ATPase family. (819 aa)
	W7A324_COCMI	Uncharacterized protein. (315 aa)
	W6YL58_COCMI	Uncharacterized protein. (319 aa)
	W6YNM9_COCMI	ER membrane protein complex subunit 4; Belongs to the EMC4 family. (184 aa)
	W6YRZ3_COCMI	Uncharacterized protein. (1209 aa)
	W6YSR8_COCMI	Uncharacterized protein. (505 aa)
	W6YSY8_COCMI	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (495 aa)
	W6YT16_COCMI	Uncharacterized protein. (102 aa)
	W6YT86_COCMI	Uncharacterized protein. (189 aa)
	W6YTP0_COCMI	TPR_REGION domain-containing protein. (326 aa)
	W6YTT0_COCMI	ATPase_AAA_core domain-containing protein. (548 aa)
	W6YVX5_COCMI	Signal peptidase subunit 3. (257 aa)
	W6YX28_COCMI	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (165 aa)
	W6YX51_COCMI	Sec39 domain-containing protein. (932 aa)
	W6YXZ1_COCMI	EMC1_C domain-containing protein. (937 aa)
	W6YZE0_COCMI	Uncharacterized protein. (333 aa)
	MMM1	Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] (494 aa)
	W6Z053_COCMI	Signal peptidase complex catalytic subunit SEC11. (173 aa)
	W6Z0Q6_COCMI	Uncharacterized protein. (225 aa)
	GET3	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (339 aa)
	W6Z1P6_COCMI	DUF2012 domain-containing protein. (240 aa)
	W6Z1S3_COCMI	J domain-containing protein. (690 aa)
	W6Z2B0_COCMI	Zn(2)-C6 fungal-type domain-containing protein. (495 aa)
	MDM12	Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...] (424 aa)
	W6Z333_COCMI	Uncharacterized protein. (345 aa)
	W6Z407_COCMI	Uncharacterized protein. (274 aa)
	W6Z416_COCMI	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (626 aa)
	W6Z498_COCMI	Aminotran_1_2 domain-containing protein. (663 aa)
	W6Z4I2_COCMI	Uncharacterized protein; Belongs to the heat shock protein 70 family. (675 aa)
	W6Z4T5_COCMI	Glycoside hydrolase family 31 protein; Belongs to the glycosyl hydrolase 31 family. (996 aa)
	W6Z5J9_COCMI	Uncharacterized protein. (423 aa)
	W6Z5L6_COCMI	FHA domain-containing protein. (804 aa)
	W6Z5L9_COCMI	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (296 aa)
	W6Z5Y4_COCMI	Uncharacterized protein. (204 aa)
	W6Z699_COCMI	Glycosyltransferase family 4 protein. (511 aa)
	W6Z7L8_COCMI	Uncharacterized protein. (136 aa)
	W6Z899_COCMI	Zn(2)-C6 fungal-type domain-containing protein. (506 aa)
	W6Z8M1_COCMI	Uncharacterized protein. (231 aa)
	W6Z9C8_COCMI	Uncharacterized protein. (665 aa)
	W6Z9V5_COCMI	Uncharacterized protein. (228 aa)
	W6Z9W6_COCMI	Uncharacterized protein. (458 aa)
	W6ZA35_COCMI	Glycosyltransferase family 39 protein. (1121 aa)
	MDM10	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...] (392 aa)
	W6ZCQ9_COCMI	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (377 aa)
	W6ZCS0_COCMI	Uncharacterized protein. (209 aa)
	W6ZD22_COCMI	Uncharacterized protein. (870 aa)
	W6ZDE8_COCMI	Glycoside hydrolase family 31 protein; Belongs to the glycosyl hydrolase 31 family. (564 aa)
	W6ZDH8_COCMI	Uncharacterized protein. (568 aa)
	W6ZDM7_COCMI	Plug_translocon domain-containing protein. (476 aa)
	W6ZDR4_COCMI	Uncharacterized protein. (405 aa)
	MDM34	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (612 aa)
	W6ZEK7_COCMI	Uncharacterized protein. (710 aa)
	W6ZEM4_COCMI	Uncharacterized protein. (563 aa)
	W6ZFL7_COCMI	LRRNT_2 domain-containing protein. (306 aa)
	cyn1	Cyanate hydratase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family. (201 aa)
	W6ZG75_COCMI	Erf4 domain-containing protein. (415 aa)
	W6ZG86_COCMI	Uncharacterized protein. (584 aa)
	W6ZGC1_COCMI	Uncharacterized protein. (202 aa)
	W6ZI38_COCMI	Uncharacterized protein. (69 aa)
	W6ZI39_COCMI	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (465 aa)
	W6ZIW5_COCMI	Glycosyltransferase family 66 protein. (751 aa)
	W6ZIW9_COCMI	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family. (260 aa)
	GET1	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. (216 aa)
	W6ZJE8_COCMI	Glycosyltransferase family 1 protein. (305 aa)
	W6ZLL4_COCMI	Aminotran_1_2 domain-containing protein. (508 aa)
	W6ZMN2_COCMI	Uncharacterized protein. (330 aa)

Your Current Organism:

Bipolaris oryzae

NCBI taxonomy Id: 930090
Other names: B. oryzae ATCC 44560, Bipolaris oryzae ATCC 44560, Cochliobolus miyabeanus ATCC 44560, Cochliobolus miyabeanus WK-1C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GET1	GET3	W6ZJ71	W6Z0T5	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.997
GET1	MDM34	W6ZJ71	W6ZDY5	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	0.568
GET1	W6YSR8_COCMI	W6ZJ71	W6YSR8	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	Uncharacterized protein.	0.688
GET1	W6Z2B0_COCMI	W6ZJ71	W6Z2B0	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	Zn(2)-C6 fungal-type domain-containing protein.	0.708
GET1	W6Z5Y4_COCMI	W6ZJ71	W6Z5Y4	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	Uncharacterized protein.	0.482
GET1	W6Z899_COCMI	W6ZJ71	W6Z899	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	Zn(2)-C6 fungal-type domain-containing protein.	0.708
GET1	W6ZDM7_COCMI	W6ZJ71	W6ZDM7	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	Plug_translocon domain-containing protein.	0.593
GET1	W6ZDR4_COCMI	W6ZJ71	W6ZDR4	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	Uncharacterized protein.	0.708
GET1	W6ZIW9_COCMI	W6ZJ71	W6ZIW9	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family.	0.579
GET1	W7A324_COCMI	W6ZJ71	W7A324	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	Uncharacterized protein.	0.708
GET3	GET1	W6Z0T5	W6ZJ71	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	0.997
GET3	W6YSR8_COCMI	W6Z0T5	W6YSR8	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Uncharacterized protein.	0.630
GET3	W6Z2B0_COCMI	W6Z0T5	W6Z2B0	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Zn(2)-C6 fungal-type domain-containing protein.	0.702
GET3	W6Z5Y4_COCMI	W6Z0T5	W6Z5Y4	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Uncharacterized protein.	0.558
GET3	W6Z899_COCMI	W6Z0T5	W6Z899	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Zn(2)-C6 fungal-type domain-containing protein.	0.702
GET3	W6ZDM7_COCMI	W6Z0T5	W6ZDM7	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Plug_translocon domain-containing protein.	0.666
GET3	W6ZDR4_COCMI	W6Z0T5	W6ZDR4	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Uncharacterized protein.	0.702
GET3	W6ZIW9_COCMI	W6Z0T5	W6ZIW9	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family.	0.517
GET3	W7A324_COCMI	W6Z0T5	W7A324	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Uncharacterized protein.	0.702
MDM10	MDM12	W6ZBD3	W6Z2N2	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...]	0.898