(49 nodes) Pyruvate metabolism network (Bipolaris oryzae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	W6YPA0_COCMI	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (491 aa)
	W6YQT9_COCMI	Malate dehydrogenase. (339 aa)
	W6YQX1_COCMI	Uncharacterized protein; Belongs to the cytochrome b5 family. (500 aa)
	W6YRU6_COCMI	Pyruvate carboxyltransferase domain-containing protein. (638 aa)
	W6YUB2_COCMI	AcetylCoA_hyd_C domain-containing protein. (531 aa)
	W6YVD6_COCMI	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (434 aa)
	W6YX42_COCMI	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (488 aa)
	W6YYX3_COCMI	Malic enzyme. (607 aa)
	W6YZN8_COCMI	Aldedh domain-containing protein. (361 aa)
	W6Z003_COCMI	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (479 aa)
	W6Z1D1_COCMI	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (499 aa)
	W6Z2I6_COCMI	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (339 aa)
	W6Z3T6_COCMI	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (480 aa)
	W6Z493_COCMI	FMN hydroxy acid dehydrogenase domain-containing protein. (447 aa)
	W6Z4J1_COCMI	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (495 aa)
	W6Z4P0_COCMI	Uncharacterized protein. (2286 aa)
	W6Z812_COCMI	Uncharacterized protein. (506 aa)
	W6Z8Y2_COCMI	Aldedh domain-containing protein. (494 aa)
	W6Z913_COCMI	Uncharacterized protein. (533 aa)
	W6ZA44_COCMI	Aldedh domain-containing protein. (506 aa)
	W6ZB88_COCMI	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1196 aa)
	W6ZBI0_COCMI	DJ-1_PfpI domain-containing protein. (240 aa)
	W6ZCV1_COCMI	FAD-binding PCMH-type domain-containing protein. (609 aa)
	W6ZCY8_COCMI	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (330 aa)
	W6ZDC8_COCMI	Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (485 aa)
	W6ZDW6_COCMI	Probable acetate kinase. (419 aa)
	W6ZEW0_COCMI	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (321 aa)
	W6ZEX4_COCMI	VOC domain-containing protein. (202 aa)
	W6ZFE0_COCMI	FAD-binding PCMH-type domain-containing protein. (557 aa)
	W6ZFL0_COCMI	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (484 aa)
	W6ZGX1_COCMI	Acylphosphatase. (92 aa)
	W6ZH31_COCMI	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (501 aa)
	W6ZI17_COCMI	Pyruvate kinase; Belongs to the pyruvate kinase family. (534 aa)
	W6ZI87_COCMI	Malate synthase; Belongs to the malate synthase family. (542 aa)
	W6ZID5_COCMI	Uncharacterized protein. (507 aa)
	W6ZIW4_COCMI	Lactamase_B domain-containing protein. (283 aa)
	W6ZJ22_COCMI	FAD-binding PCMH-type domain-containing protein. (489 aa)
	W6ZJS2_COCMI	Uncharacterized protein. (509 aa)
	W6ZKH3_COCMI	Acetyl-coenzyme A synthetase. (670 aa)
	W6ZKR2_COCMI	FAD-binding PCMH-type domain-containing protein. (550 aa)
	W6ZLI6_COCMI	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
	W6ZNJ8_COCMI	Malate dehydrogenase. (327 aa)
	W6ZUH6_COCMI	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (374 aa)
	W6ZVZ3_COCMI	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (426 aa)
	W6ZZK3_COCMI	Uncharacterized protein. (561 aa)
	W7A0U0_COCMI	Aldedh domain-containing protein. (230 aa)
	W7A0V0_COCMI	FAD-binding PCMH-type domain-containing protein. (218 aa)
	W7A3U6_COCMI	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (488 aa)
	W7A556_COCMI	Malic enzyme. (581 aa)

Your Current Organism:

Bipolaris oryzae

NCBI taxonomy Id: 930090
Other names: B. oryzae ATCC 44560, Bipolaris oryzae ATCC 44560, Cochliobolus miyabeanus ATCC 44560, Cochliobolus miyabeanus WK-1C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
W6YPA0_COCMI	W6YUB2_COCMI	W6YPA0	W6YUB2	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	AcetylCoA_hyd_C domain-containing protein.	0.928
W6YPA0_COCMI	W6Z493_COCMI	W6YPA0	W6Z493	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	FMN hydroxy acid dehydrogenase domain-containing protein.	0.926
W6YPA0_COCMI	W6ZDW6_COCMI	W6YPA0	W6ZDW6	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Probable acetate kinase.	0.901
W6YPA0_COCMI	W6ZGX1_COCMI	W6YPA0	W6ZGX1	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Acylphosphatase.	0.900
W6YPA0_COCMI	W6ZKH3_COCMI	W6YPA0	W6ZKH3	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Acetyl-coenzyme A synthetase.	0.943
W6YQT9_COCMI	W6YYX3_COCMI	W6YQT9	W6YYX3	Malate dehydrogenase.	Malic enzyme.	0.955
W6YQT9_COCMI	W6Z4P0_COCMI	W6YQT9	W6Z4P0	Malate dehydrogenase.	Uncharacterized protein.	0.596
W6YQT9_COCMI	W6Z913_COCMI	W6YQT9	W6Z913	Malate dehydrogenase.	Uncharacterized protein.	0.985
W6YQT9_COCMI	W6ZB88_COCMI	W6YQT9	W6ZB88	Malate dehydrogenase.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.965
W6YQT9_COCMI	W6ZI17_COCMI	W6YQT9	W6ZI17	Malate dehydrogenase.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.782
W6YQT9_COCMI	W6ZI87_COCMI	W6YQT9	W6ZI87	Malate dehydrogenase.	Malate synthase; Belongs to the malate synthase family.	0.974
W6YQT9_COCMI	W6ZNJ8_COCMI	W6YQT9	W6ZNJ8	Malate dehydrogenase.	Malate dehydrogenase.	0.902
W6YQT9_COCMI	W6ZUH6_COCMI	W6YQT9	W6ZUH6	Malate dehydrogenase.	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.634
W6YQT9_COCMI	W6ZVZ3_COCMI	W6YQT9	W6ZVZ3	Malate dehydrogenase.	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.616
W6YQT9_COCMI	W6ZZK3_COCMI	W6YQT9	W6ZZK3	Malate dehydrogenase.	Uncharacterized protein.	0.944
W6YQT9_COCMI	W7A556_COCMI	W6YQT9	W7A556	Malate dehydrogenase.	Malic enzyme.	0.955
W6YQX1_COCMI	W6YRU6_COCMI	W6YQX1	W6YRU6	Uncharacterized protein; Belongs to the cytochrome b5 family.	Pyruvate carboxyltransferase domain-containing protein.	0.828
W6YQX1_COCMI	W6YYX3_COCMI	W6YQX1	W6YYX3	Uncharacterized protein; Belongs to the cytochrome b5 family.	Malic enzyme.	0.916
W6YQX1_COCMI	W6Z493_COCMI	W6YQX1	W6Z493	Uncharacterized protein; Belongs to the cytochrome b5 family.	FMN hydroxy acid dehydrogenase domain-containing protein.	0.913
W6YQX1_COCMI	W6ZB88_COCMI	W6YQX1	W6ZB88	Uncharacterized protein; Belongs to the cytochrome b5 family.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.929