STRINGSTRING
ADX71339.1 ADX71339.1 ADX72212.1 ADX72212.1 ADX72213.1 ADX72213.1 ADX72220.1 ADX72220.1 ADX72225.1 ADX72225.1 ADX72256.1 ADX72256.1 ADX72303.1 ADX72303.1 ADX72314.1 ADX72314.1 ADX72320.1 ADX72320.1 ADX72495.1 ADX72495.1 dxr dxr hisD hisD ADX72796.1 ADX72796.1 ADX72816.1 ADX72816.1 ADX72878.1 ADX72878.1 ADX72892.1 ADX72892.1 ADX72934.1 ADX72934.1 zwf zwf ADX73135.1 ADX73135.1 ADX73159.1 ADX73159.1 ADX73170.1 ADX73170.1 ADX73247.1 ADX73247.1 ADX73269.1 ADX73269.1 ADX73442.1 ADX73442.1 ADX73461.1 ADX73461.1 zwf-2 zwf-2 gpsA gpsA leuB leuB ADX73536.1 ADX73536.1 ilvC ilvC mqo mqo ADX73616.1 ADX73616.1 ADX73628.1 ADX73628.1 ADX73656.1 ADX73656.1 ADX73837.1 ADX73837.1 ADX73838.1 ADX73838.1 guaB guaB ADX73852.1 ADX73852.1 ADX73862.1 ADX73862.1 murB murB ADX74030.1 ADX74030.1 ADX74253.1 ADX74253.1 ADX74296.1 ADX74296.1 ADX74357.1 ADX74357.1 ADX74369.1 ADX74369.1 ADX74375.1 ADX74375.1 ADX74378.1 ADX74378.1 ADX74413.1 ADX74413.1 ADX74453.1 ADX74453.1 ADX74458.1 ADX74458.1 ADX74482.1 ADX74482.1 ADX74509.1 ADX74509.1 ADX74552.1 ADX74552.1 ADX74555.1 ADX74555.1 ADX74579.1 ADX74579.1 ADX74709.1 ADX74709.1 ADX74722.1 ADX74722.1 ADX74742.1 ADX74742.1 ADX74752.1 ADX74752.1 ldh ldh ADX74908.1 ADX74908.1 mtlD mtlD ADX74924.1 ADX74924.1 aroE aroE ADX74982.1 ADX74982.1 ADX75025.1 ADX75025.1 ADX72134.1 ADX72134.1 ADX72117.1 ADX72117.1 ADX72066.1 ADX72066.1 ADX72064.1 ADX72064.1 iolG iolG ADX71908.1 ADX71908.1 ADX71894.1 ADX71894.1 ADX71891.1 ADX71891.1 ADX71885.1 ADX71885.1 ADX71814.1 ADX71814.1 ADX71811.1 ADX71811.1 ADX71810.1 ADX71810.1 ADX71418.1 ADX71418.1 ADX71404.1 ADX71404.1 ADX71401.1 ADX71401.1 ADX71394.1 ADX71394.1 ADX71388.1 ADX71388.1 ADX71352.1 ADX71352.1 ADX71349.1 ADX71349.1 ADX71328.1 ADX71328.1 ADX71326.1 ADX71326.1 ADX71270.1 ADX71270.1 ADX71225.1 ADX71225.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ADX71339.1PFAM: Malate/L-lactate dehydrogenase; Belongs to the LDH2/MDH2 oxidoreductase family. (346 aa)
ADX72212.1PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase. (353 aa)
ADX72213.1PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain. (490 aa)
ADX72220.1Theronine dehydrogenase-like Zn-dependent dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (351 aa)
ADX72225.1PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (344 aa)
ADX72256.1Putative dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. (390 aa)
ADX72303.1Putative UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase. (459 aa)
ADX72314.1PFAM: Monomeric isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, monomeric type; Belongs to the monomeric-type IDH family. (739 aa)
ADX72320.1Putative dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. (359 aa)
ADX72495.1L-threonine 3-dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: L-threonine 3-dehydrogenase. (348 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (394 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (455 aa)
ADX72796.1PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (719 aa)
ADX72816.1Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (386 aa)
ADX72878.1PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase. (360 aa)
ADX72892.1Putative dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. (326 aa)
ADX72934.1Dihydrofolate reductase; PFAM: RibD C-terminal domain. (188 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (522 aa)
ADX73135.1Glycerol-3-phosphate dehydrogenase; PFAM: FAD dependent oxidoreductase. (619 aa)
ADX73159.1PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (330 aa)
ADX73170.1PFAM: Shikimate dehydrogenase substrate binding domain; Shikimate / quinate 5-dehydrogenase; TIGRFAM: shikimate 5-dehydrogenase. (286 aa)
ADX73247.1PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: zinc-binding alcohol dehydrogenase family protein. (332 aa)
ADX73269.1Theronine dehydrogenase-like Zn-dependent dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (351 aa)
ADX73442.1Putative dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold. (389 aa)
ADX73461.16-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (478 aa)
zwf-2Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (467 aa)
gpsAPFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (350 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (350 aa)
ADX73536.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: D-3-phosphoglycerate dehydrogenase. (529 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (341 aa)
mqoMalate:quinone-oxidoreductase; PFAM: Malate:quinone oxidoreductase (Mqo); TIGRFAM: malate:quinone-oxidoreductase. (500 aa)
ADX73616.1PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. (435 aa)
ADX73628.1PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (395 aa)
ADX73656.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (482 aa)
ADX73837.1Glycerol-3-phosphate dehydrogenase; PFAM: FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (579 aa)
ADX73838.1PFAM: IMP dehydrogenase / GMP reductase domain; TIGRFAM: IMP dehydrogenase family protein. (378 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (503 aa)
ADX73852.1PFAM: Shikimate dehydrogenase substrate binding domain; Shikimate / quinate 5-dehydrogenase; TIGRFAM: shikimate 5-dehydrogenase. (265 aa)
ADX73862.1PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain. (468 aa)
murBUDP-N-acetylmuramate dehydrogenase; Cell wall formation. (351 aa)
ADX74030.1PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (336 aa)
ADX74253.1Theronine dehydrogenase-like Zn-dependent dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain. (174 aa)
ADX74296.1PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (291 aa)
ADX74357.1Putative dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold. (414 aa)
ADX74369.1Putative dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold. (687 aa)
ADX74375.1Putative dehydrogenase; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold. (477 aa)
ADX74378.1Alpha-hydroxyacid dehydrogenase, FMN-dependent L-lactate dehydrogenase; PFAM: FMN-dependent dehydrogenase. (447 aa)
ADX74413.1Putative dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold. (400 aa)
ADX74453.1PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain. (481 aa)
ADX74458.1Theronine dehydrogenase-like Zn-dependent dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (391 aa)
ADX74482.1Putative dehydrogenase; PFAM: FAD dependent oxidoreductase. (397 aa)
ADX74509.1PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (346 aa)
ADX74552.1PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: formaldehyde dehydrogenase, glutathione-independent. (405 aa)
ADX74555.1Putative dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold. (368 aa)
ADX74579.1Choline dehydrogenase-like flavoprotein; PFAM: GMC oxidoreductase. (550 aa)
ADX74709.1Putative dehydrogenase; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold. (444 aa)
ADX74722.1Putative oxidoreductase, aryl-alcohol dehydrogenase like protein; PFAM: Aldo/keto reductase family. (330 aa)
ADX74742.1Putative dehydrogenase; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold. (347 aa)
ADX74752.1Putative dehydrogenase; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold. (377 aa)
ldhMalate dehydrogenase (NAD); Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (315 aa)
ADX74908.1PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain. (399 aa)
mtlDD-mannitol 1-phosphate 5-dehydrogenase; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain. (387 aa)
ADX74924.1Putative dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. (353 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (293 aa)
ADX74982.1PFAM: Luciferase-like monooxygenase; TIGRFAM: F420-dependent oxidoreductase, G6PDH family. (326 aa)
ADX75025.1Putative dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold. (374 aa)
ADX72134.1Putative dehydrogenase; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold. (380 aa)
ADX72117.1PFAM: Alcohol dehydrogenase GroES-like domain; TIGRFAM: formaldehyde dehydrogenase, glutathione-independent. (404 aa)
ADX72066.1Putative dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. (347 aa)
ADX72064.1Putative dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold. (362 aa)
iolGPutative dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose). (337 aa)
ADX71908.1Theronine dehydrogenase-like Zn-dependent dehydrogenase. (342 aa)
ADX71894.1PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain. (475 aa)
ADX71891.1Putative dehydrogenase; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold. (388 aa)
ADX71885.1Putative dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. (336 aa)
ADX71814.1Phosphoglycerate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (319 aa)
ADX71811.1Putative dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold. (380 aa)
ADX71810.1Putative dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. (400 aa)
ADX71418.1Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. (569 aa)
ADX71404.1Pyranose oxidase; PFAM: GMC oxidoreductase; TIGRFAM: pyranose oxidase. (525 aa)
ADX71401.1Putative dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold. (346 aa)
ADX71394.1Putative dehydrogenase; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold. (395 aa)
ADX71388.1Pyranose oxidase; PFAM: GMC oxidoreductase; TIGRFAM: pyranose oxidase. (519 aa)
ADX71352.1Putative dehydrogenase; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold. (396 aa)
ADX71349.1Putative dehydrogenase; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold. (375 aa)
ADX71328.1Putative dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold. (388 aa)
ADX71326.1Choline dehydrogenase-like flavoprotein; PFAM: GMC oxidoreductase. (522 aa)
ADX71270.1FAD/FMN-dependent dehydrogenase; PFAM: D-arabinono-1,4-lactone oxidase; FAD binding domain. (418 aa)
ADX71225.1PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase, C-terminal domain; TIGRFAM: 6-phosphogluconate dehydrogenase (decarboxylating). (294 aa)
Your Current Organism:
Pseudarthrobacter phenanthrenivorans
NCBI taxonomy Id: 930171
Other names: Arthrobacter phenanthrenivorans Sphe3, Arthrobacter sp. Sphe3, P. phenanthrenivorans Sphe3, Pseudarthrobacter phenanthrenivorans Sphe3
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