(6 nodes) Mixed, incl. Phosphatase 2C, C-terminal domain superfamily, and ISG15-protein conjugation network (Sarcophilus harrisii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HERC3	Uncharacterized protein. (651 aa)
	G3VE88_SARHA	HECT domain-containing protein. (352 aa)
	PPM1A	Protein phosphatase, Mg2+/Mn2+ dependent 1A. (382 aa)
	UBE2L6	Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
	ARIH1	RBR-type E3 ubiquitin transferase. (444 aa)
	PPM1B	PPM-type phosphatase domain-containing protein. (479 aa)

Your Current Organism:

Sarcophilus harrisii

NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARIH1	G3VE88_SARHA	ENSSHAP00000019044	ENSSHAP00000001492	RBR-type E3 ubiquitin transferase.	HECT domain-containing protein.	0.408
ARIH1	HERC3	ENSSHAP00000019044	ENSSHAP00000000791	RBR-type E3 ubiquitin transferase.	Uncharacterized protein.	0.408
ARIH1	PPM1A	ENSSHAP00000019044	ENSSHAP00000017052	RBR-type E3 ubiquitin transferase.	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	0.526
ARIH1	PPM1B	ENSSHAP00000019044	ENSSHAP00000021891	RBR-type E3 ubiquitin transferase.	PPM-type phosphatase domain-containing protein.	0.574
ARIH1	UBE2L6	ENSSHAP00000019044	ENSSHAP00000018211	RBR-type E3 ubiquitin transferase.	Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family.	0.952
G3VE88_SARHA	ARIH1	ENSSHAP00000001492	ENSSHAP00000019044	HECT domain-containing protein.	RBR-type E3 ubiquitin transferase.	0.408
G3VE88_SARHA	HERC3	ENSSHAP00000001492	ENSSHAP00000000791	HECT domain-containing protein.	Uncharacterized protein.	0.899
G3VE88_SARHA	UBE2L6	ENSSHAP00000001492	ENSSHAP00000018211	HECT domain-containing protein.	Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family.	0.576
HERC3	ARIH1	ENSSHAP00000000791	ENSSHAP00000019044	Uncharacterized protein.	RBR-type E3 ubiquitin transferase.	0.408
HERC3	G3VE88_SARHA	ENSSHAP00000000791	ENSSHAP00000001492	Uncharacterized protein.	HECT domain-containing protein.	0.899
HERC3	UBE2L6	ENSSHAP00000000791	ENSSHAP00000018211	Uncharacterized protein.	Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family.	0.576
PPM1A	ARIH1	ENSSHAP00000017052	ENSSHAP00000019044	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	RBR-type E3 ubiquitin transferase.	0.526
PPM1A	PPM1B	ENSSHAP00000017052	ENSSHAP00000021891	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	PPM-type phosphatase domain-containing protein.	0.615
PPM1A	UBE2L6	ENSSHAP00000017052	ENSSHAP00000018211	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family.	0.472
PPM1B	ARIH1	ENSSHAP00000021891	ENSSHAP00000019044	PPM-type phosphatase domain-containing protein.	RBR-type E3 ubiquitin transferase.	0.574
PPM1B	PPM1A	ENSSHAP00000021891	ENSSHAP00000017052	PPM-type phosphatase domain-containing protein.	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	0.615
PPM1B	UBE2L6	ENSSHAP00000021891	ENSSHAP00000018211	PPM-type phosphatase domain-containing protein.	Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family.	0.472
UBE2L6	ARIH1	ENSSHAP00000018211	ENSSHAP00000019044	Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family.	RBR-type E3 ubiquitin transferase.	0.952
UBE2L6	G3VE88_SARHA	ENSSHAP00000018211	ENSSHAP00000001492	Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family.	HECT domain-containing protein.	0.576
UBE2L6	HERC3	ENSSHAP00000018211	ENSSHAP00000000791	Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family.	Uncharacterized protein.	0.576