(66 nodes) Mixed, incl. Putative peptidoglycan binding domain, and ECM proteoglycans network (Sarcophilus harrisii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	COL18A1	Endostatin domain-containing protein. (176 aa)
	OMD	Osteomodulin. (434 aa)
	G3VBF3_SARHA	Uncharacterized protein. (845 aa)
	G3VBI2_SARHA	TB domain-containing protein. (568 aa)
	ASPN	LRRNT domain-containing protein. (195 aa)
	G3VC04_SARHA	Uncharacterized protein. (159 aa)
	G3VCD5_SARHA	LAM_G_DOMAIN domain-containing protein. (904 aa)
	LOXL1	Uncharacterized protein. (171 aa)
	ELN	Uncharacterized protein. (578 aa)
	TNMD	Tenomodulin. (320 aa)
	SERPINB1	Serpin family B member 1; Belongs to the serpin family. (379 aa)
	MMP16	Matrix metallopeptidase 16. (479 aa)
	MMP11	Matrix metallopeptidase 11. (404 aa)
	MMP28	Matrix metallopeptidase 28. (497 aa)
	KERA	Keratocan. (352 aa)
	HAPLN1	Hyaluronan and proteoglycan link protein 1. (356 aa)
	G3VSK1_SARHA	PG_binding_1 domain-containing protein. (102 aa)
	MMP9	Matrix metallopeptidase 9. (717 aa)
	FBN3	Fibrillin 3. (2856 aa)
	NID2	Nidogen 2. (1404 aa)
	FRZB	Frizzled related protein. (321 aa)
	MMP15	Matrix metallopeptidase 15. (512 aa)
	TIMP4	TIMP metallopeptidase inhibitor 4. (225 aa)
	MATN3	Matrilin 3. (423 aa)
	VCAN	Versican. (3404 aa)
	NID1	Uncharacterized protein. (79 aa)
	FBLN2	Fibulin 2. (1188 aa)
	FBLN1	Fibulin 1. (570 aa)
	FBLN5	Fibulin 5. (444 aa)
	MFAP5	Microfibril associated protein 5. (168 aa)
	MFAP2	Microfibril associated protein 2. (176 aa)
	MMP19	Matrix metallopeptidase 19. (497 aa)
	G3W4M4_SARHA	Fibrinogen C-terminal domain-containing protein. (238 aa)
	TNC	Tenascin C. (1730 aa)
	COMP	Cartilage oligomeric matrix protein. (761 aa)
	MMP21	Matrix metallopeptidase 21. (528 aa)
	G3WCD1_SARHA	Uncharacterized protein. (178 aa)
	G3WEC7_SARHA	Uncharacterized protein. (1313 aa)
	MMP2	Matrix metallopeptidase 2. (665 aa)
	MMP14	Matrix metallopeptidase 14. (580 aa)
	PCSK4	Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (690 aa)
	MMP7	ZnMc domain-containing protein. (264 aa)
	ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif 5. (942 aa)
	MATN4	Uncharacterized protein. (607 aa)
	G3WK21_SARHA	VWFA domain-containing protein. (260 aa)
	MFAP4	Microfibril associated protein 4. (277 aa)
	MMP17	Matrix metallopeptidase 17. (566 aa)
	MMP27	Matrix metallopeptidase 27. (512 aa)
	MMP8	Matrix metallopeptidase 8. (480 aa)
	ANGPTL2	Angiopoietin like 2. (492 aa)
	MMP1	Matrix metallopeptidase 1. (473 aa)
	MMP3	Matrix metallopeptidase 3. (474 aa)
	G3WNV3_SARHA	ZnMc domain-containing protein. (473 aa)
	MMP13	Matrix metallopeptidase 13. (474 aa)
	BCAN	Brevican. (773 aa)
	HBEGF	Heparin binding EGF like growth factor. (210 aa)
	ACAN	Aggrecan. (2026 aa)
	ADAMTS4	ADAM metallopeptidase with thrombospondin type 1 motif 4. (844 aa)
	TIMP2	TIMP metallopeptidase inhibitor 2. (176 aa)
	G3WXC7_SARHA	Uncharacterized protein. (454 aa)
	TIMP3	TIMP metallopeptidase inhibitor 3. (171 aa)
	G3WXH5_SARHA	Uncharacterized protein. (1113 aa)
	PRELP	Proline and arginine rich end leucine rich repeat protein. (387 aa)
	MMP25	Matrix metallopeptidase 25. (562 aa)
	CNMD	Chondromodulin. (335 aa)
	MMP24	Matrix metallopeptidase 24. (582 aa)

Your Current Organism:

Sarcophilus harrisii

NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAN	ADAMTS4	ENSSHAP00000019365	ENSSHAP00000019511	Aggrecan.	ADAM metallopeptidase with thrombospondin type 1 motif 4.	0.746
ACAN	ADAMTS5	ENSSHAP00000019365	ENSSHAP00000015111	Aggrecan.	ADAM metallopeptidase with thrombospondin type 1 motif 5.	0.746
ACAN	ASPN	ENSSHAP00000019365	ENSSHAP00000000571	Aggrecan.	LRRNT domain-containing protein.	0.568
ACAN	BCAN	ENSSHAP00000019365	ENSSHAP00000018302	Aggrecan.	Brevican.	0.724
ACAN	COMP	ENSSHAP00000019365	ENSSHAP00000011068	Aggrecan.	Cartilage oligomeric matrix protein.	0.746
ACAN	ELN	ENSSHAP00000019365	ENSSHAP00000001267	Aggrecan.	Uncharacterized protein.	0.547
ACAN	FBLN1	ENSSHAP00000019365	ENSSHAP00000009181	Aggrecan.	Fibulin 1.	0.625
ACAN	FBLN2	ENSSHAP00000019365	ENSSHAP00000008842	Aggrecan.	Fibulin 2.	0.582
ACAN	G3VC04_SARHA	ENSSHAP00000019365	ENSSHAP00000000708	Aggrecan.	Uncharacterized protein.	0.599
ACAN	G3WEC7_SARHA	ENSSHAP00000019365	ENSSHAP00000013782	Aggrecan.	Uncharacterized protein.	0.597
ACAN	G3WXC7_SARHA	ENSSHAP00000019365	ENSSHAP00000020082	Aggrecan.	Uncharacterized protein.	0.582
ACAN	G3WXH5_SARHA	ENSSHAP00000019365	ENSSHAP00000020130	Aggrecan.	Uncharacterized protein.	0.446
ACAN	HAPLN1	ENSSHAP00000019365	ENSSHAP00000006125	Aggrecan.	Hyaluronan and proteoglycan link protein 1.	0.913
ACAN	KERA	ENSSHAP00000019365	ENSSHAP00000005294	Aggrecan.	Keratocan.	0.577
ACAN	MATN3	ENSSHAP00000019365	ENSSHAP00000008039	Aggrecan.	Matrilin 3.	0.528
ACAN	MMP1	ENSSHAP00000019365	ENSSHAP00000016610	Aggrecan.	Matrix metallopeptidase 1.	0.425
ACAN	MMP13	ENSSHAP00000019365	ENSSHAP00000017481	Aggrecan.	Matrix metallopeptidase 13.	0.679
ACAN	MMP9	ENSSHAP00000019365	ENSSHAP00000006723	Aggrecan.	Matrix metallopeptidase 9.	0.473
ACAN	OMD	ENSSHAP00000019365	ENSSHAP00000000449	Aggrecan.	Osteomodulin.	0.568
ACAN	PRELP	ENSSHAP00000019365	ENSSHAP00000020458	Aggrecan.	Proline and arginine rich end leucine rich repeat protein.	0.577