STRINGSTRING
TTK TTK DYRK4 DYRK4 WNK3 WNK3 CDK10 CDK10 PKN1 PKN1 TSSK4 TSSK4 CSNK2A2 CSNK2A2 WNK1 WNK1 KIAA1549 KIAA1549 CSNK2B CSNK2B G3VDH5_SARHA G3VDH5_SARHA G3VBU2_SARHA G3VBU2_SARHA HIPK3 HIPK3 DYRK3 DYRK3 BCL2 BCL2 CHEK1 CHEK1 ACVR1 ACVR1 CDK1 CDK1 TGFBR1 TGFBR1 LRRK2 LRRK2 GSK3B GSK3B CDC42BPG CDC42BPG TBK1 TBK1 CDC42BPB CDC42BPB CSNK2A1 CSNK2A1 STK11 STK11 PDPK1 PDPK1 PRKCD PRKCD PRKCB PRKCB PRKCA PRKCA CDK5 CDK5 DCAF1 DCAF1 ATF2 ATF2 G3WDH0_SARHA G3WDH0_SARHA NLK NLK ACVR1B ACVR1B DYRK1A DYRK1A ROCK2 ROCK2 TGFBR2 TGFBR2 CAD CAD DYRK2 DYRK2 G3WI92_SARHA G3WI92_SARHA MTOR MTOR MYLK2 MYLK2 TTBK1 TTBK1 VRK1 VRK1 ULK1 ULK1 HIPK1 HIPK1 PRKDC PRKDC ROCK1 ROCK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TTKTTK protein kinase. (843 aa)
DYRK4Dual specificity tyrosine phosphorylation regulated kinase 4. (646 aa)
WNK3Protein kinase domain-containing protein. (635 aa)
CDK10Cyclin dependent kinase 10. (378 aa)
PKN1Protein kinase N1. (937 aa)
TSSK4Testis specific serine kinase 4. (342 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (320 aa)
WNK1WNK lysine deficient protein kinase 1. (2151 aa)
KIAA1549KIAA1549. (1900 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (234 aa)
G3VDH5_SARHAProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (387 aa)
G3VBU2_SARHAUncharacterized protein. (861 aa)
HIPK3Homeodomain interacting protein kinase 3. (1281 aa)
DYRK3Dual specificity tyrosine phosphorylation regulated kinase 3. (588 aa)
BCL2BCL2 apoptosis regulator. (227 aa)
CHEK1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (476 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (475 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
GSK3BGlycogen synthase kinase 3 beta. (259 aa)
CDC42BPGUncharacterized protein; Belongs to the protein kinase superfamily. (342 aa)
TBK1TANK binding kinase 1. (732 aa)
CDC42BPBCDC42 binding protein kinase beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1713 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
STK11Serine/threonine kinase 11. (252 aa)
PDPK1Protein kinase domain-containing protein. (558 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (677 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (613 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (578 aa)
CDK5Cyclin dependent kinase 5. (307 aa)
DCAF1DDB1 and CUL4 associated factor 1. (1433 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (503 aa)
G3WDH0_SARHAProtein kinase domain-containing protein. (512 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (444 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (473 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (754 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1410 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (409 aa)
CADCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2208 aa)
DYRK2Dual specificity tyrosine phosphorylation regulated kinase 2. (584 aa)
G3WI92_SARHAPoly [ADP-ribose] polymerase. (1090 aa)
MTORSerine/threonine-protein kinase mTOR. (1680 aa)
MYLK2Myosin light chain kinase 2. (632 aa)
TTBK1Tau tubulin kinase 1. (1337 aa)
VRK1VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily. (396 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1063 aa)
HIPK1Homeodomain interacting protein kinase 1. (1207 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4154 aa)
ROCK1Uncharacterized protein. (516 aa)
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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