(107 nodes) Cytosolic ribosome network (Sarcophilus harrisii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3VJX7_SARHA	Uncharacterized protein; Belongs to the universal ribosomal protein uL22 family. (185 aa)
	LOC100923548	Uncharacterized protein. (117 aa)
	RPLP2	Ribosomal protein lateral stalk subunit P2; Belongs to the eukaryotic ribosomal protein P1/P2 family. (116 aa)
	RPL21	Uncharacterized protein. (161 aa)
	RPS10	S10_plectin domain-containing protein. (165 aa)
	G3VBL6_SARHA	Uncharacterized protein. (60 aa)
	RPL18A	60S ribosomal protein L18a; Belongs to the eukaryotic ribosomal protein eL20 family. (165 aa)
	RPL27A	Ribosomal_L18e/L15P domain-containing protein; Belongs to the universal ribosomal protein uL15 family. (148 aa)
	RPS8	Ribosomal protein S8. (188 aa)
	RPS5	Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (204 aa)
	LOC100926189	Uncharacterized protein; Belongs to the universal ribosomal protein uS11 family. (127 aa)
	RPL12	Ribosomal protein L12; Belongs to the universal ribosomal protein uL11 family. (182 aa)
	EIF2D	Uncharacterized protein. (583 aa)
	G3WYA6_SARHA	Uncharacterized protein. (825 aa)
	RPS27L	40S ribosomal protein S27. (84 aa)
	RPL23	Ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family. (140 aa)
	G3WXI5_SARHA	Ribosomal_L30 domain-containing protein. (194 aa)
	G3WXD3_SARHA	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (226 aa)
	RPL19	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (196 aa)
	G3WVD7_SARHA	Uncharacterized protein. (574 aa)
	G3WST0_SARHA	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (125 aa)
	RPS2	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (293 aa)
	RPS3A-2	40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3. (260 aa)
	RPLP1	Ribosomal protein lateral stalk subunit P1; Belongs to the eukaryotic ribosomal protein P1/P2 family. (114 aa)
	RPL23A	Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family. (156 aa)
	LOC100915376	Uncharacterized protein. (247 aa)
	RPL7	Uncharacterized protein. (245 aa)
	G3WMS6_SARHA	Ribosomal_L23eN domain-containing protein. (137 aa)
	RPL37	Ribosomal protein L37; Binds to the 23S rRNA. (97 aa)
	G3WKU0_SARHA	Uncharacterized protein. (325 aa)
	RPS21	40S ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family. (83 aa)
	RPL8	Ribosomal protein L8. (257 aa)
	RPL36	60S ribosomal protein L36; Belongs to the eukaryotic ribosomal protein eL36 family. (105 aa)
	G3WK68_SARHA	Uncharacterized protein. (169 aa)
	RPS15	Uncharacterized protein; Belongs to the universal ribosomal protein uS19 family. (145 aa)
	RPL37A	Ribosomal protein L37a. (92 aa)
	G3WJP8_SARHA	Ribosomal_L7Ae domain-containing protein. (115 aa)
	G3WIS3_SARHA	Ribosomal_L23eN domain-containing protein. (146 aa)
	RPS7	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (185 aa)
	G3WHV2_SARHA	Uncharacterized protein. (160 aa)
	RPL32	Ribosomal protein L32. (135 aa)
	RPL27	60S ribosomal protein L27; Belongs to the eukaryotic ribosomal protein eL27 family. (136 aa)
	RPL31	Uncharacterized protein. (125 aa)
	RPL26-2	Ribosomal protein L26 like 1. (145 aa)
	RPL7L1	Ribosomal protein L7 like 1. (244 aa)
	RPS3	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (242 aa)
	FANCE	FA_FANCE domain-containing protein. (490 aa)
	RPL30	Ribosomal_L7Ae domain-containing protein. (115 aa)
	LOC100914101	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (124 aa)
	G3WB79_SARHA	Ribosomal_L7Ae domain-containing protein. (118 aa)
	RPS25	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (119 aa)
	G3W9T5_SARHA	Ribosomal_L7Ae domain-containing protein. (84 aa)
	G3W9S0_SARHA	Uncharacterized protein. (147 aa)
	G3W643_SARHA	Uncharacterized protein. (131 aa)
	G3W5Y0_SARHA	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family. (172 aa)
	RPL14	Ribosomal protein L14. (174 aa)
	RPLP0	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (317 aa)
	MRPL1	Mitochondrial ribosomal protein L1. (327 aa)
	RPL10A	Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. (217 aa)
	RPL34	Uncharacterized protein. (117 aa)
	RPL4	Ribosomal protein L4. (428 aa)
	G3VJ63_SARHA	Uncharacterized protein. (160 aa)
	DHX29	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1341 aa)
	RPL3	Uncharacterized protein; Belongs to the universal ribosomal protein uL3 family. (407 aa)
	RPL10	Ribosomal protein L10. (214 aa)
	RPL35A	Uncharacterized protein. (110 aa)
	RPS13	Ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family. (155 aa)
	RPL7A	Ribosomal protein L7a. (266 aa)
	RPL35	Ribosomal protein L35. (125 aa)
	RPL9	Ribosomal protein L9. (192 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (163 aa)
	RPL13A	Ribosomal protein L13a. (118 aa)
	G3VSP6_SARHA	RL10P_insert domain-containing protein. (251 aa)
	RPS29	Ribosomal protein S29. (56 aa)
	LOC100924919	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (263 aa)
	G3VTR1_SARHA	Ribosomal_L7Ae domain-containing protein. (114 aa)
	RPS4X	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (296 aa)
	G3VVE7_SARHA	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (219 aa)
	G3VVM0_SARHA	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (129 aa)
	RPL5	Ribosomal_L18_c domain-containing protein. (297 aa)
	RPL18	Ribosomal protein L18. (190 aa)
	RPL11	Ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family. (178 aa)
	SVOPL	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (149 aa)
	RPS19	Ribosomal protein S19. (157 aa)
	RPL29	60S ribosomal protein L29; Belongs to the eukaryotic ribosomal protein eL29 family. (170 aa)
	RPL26	Ribosomal protein L26. (145 aa)
	RPSA	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...] (295 aa)
	G3VY99_SARHA	Ribosomal_L6e_N domain-containing protein. (213 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	RPL6	Ribosomal_L6e_N domain-containing protein. (286 aa)
	LOC100928280	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (263 aa)
	RPS24	40S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family. (145 aa)
	RPS3A	40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3. (227 aa)
	RPS28	Uncharacterized protein. (45 aa)
	RPL24	Ribosomal protein L24. (157 aa)
	RPS23	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (143 aa)
	G3W2L5_SARHA	Uncharacterized protein. (274 aa)
	G3W2X3_SARHA	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (112 aa)
	G3W303_SARHA	Uncharacterized protein. (60 aa)
	RPL38	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family. (70 aa)
	ZCCHC17	Zinc finger CCHC-type containing 17. (240 aa)
	APOD	Apolipoprotein D. (189 aa)
	RPS12	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (132 aa)
	G3W4P9_SARHA	Uncharacterized protein. (279 aa)
	EIF2A	Eukaryotic translation initiation factor 2A. (444 aa)
	G3X2K9_SARHA	Uncharacterized protein. (551 aa)
	RPS14	Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family. (157 aa)

Your Current Organism:

Sarcophilus harrisii

NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DHX29	LOC100926189	ENSSHAP00000003414	ENSSHAP00000000062	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Uncharacterized protein; Belongs to the universal ribosomal protein uS11 family.	0.427
DHX29	RPS13	ENSSHAP00000003414	ENSSHAP00000004611	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family.	0.542
DHX29	RPS14	ENSSHAP00000003414	ENSSHAP00000021298	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	0.423
DHX29	RPS2	ENSSHAP00000003414	ENSSHAP00000017922	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	0.524
DHX29	RPS3A-2	ENSSHAP00000003414	ENSSHAP00000017772	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3.	0.553
DHX29	RPS7	ENSSHAP00000003414	ENSSHAP00000015066	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	0.467
DHX29	RPSA	ENSSHAP00000003414	ENSSHAP00000007949	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...]	0.523
EIF2D	G3W2X3_SARHA	ENSSHAP00000020952	ENSSHAP00000009778	Uncharacterized protein.	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	0.454
EIF2D	G3W5Y0_SARHA	ENSSHAP00000020952	ENSSHAP00000010835	Uncharacterized protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	0.491
EIF2D	LOC100914101	ENSSHAP00000020952	ENSSHAP00000012728	Uncharacterized protein.	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family.	0.454
EIF2D	LOC100924919	ENSSHAP00000020952	ENSSHAP00000006488	Uncharacterized protein.	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family.	0.447
EIF2D	LOC100928280	ENSSHAP00000020952	ENSSHAP00000009327	Uncharacterized protein.	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family.	0.447
EIF2D	RPS10	ENSSHAP00000020952	ENSSHAP00000000819	Uncharacterized protein.	S10_plectin domain-containing protein.	0.450
EIF2D	RPS13	ENSSHAP00000020952	ENSSHAP00000004611	Uncharacterized protein.	Ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family.	0.496
EIF2D	RPS14	ENSSHAP00000020952	ENSSHAP00000021298	Uncharacterized protein.	Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	0.450
EIF2D	RPS15	ENSSHAP00000020952	ENSSHAP00000015754	Uncharacterized protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uS19 family.	0.473
EIF2D	RPS19	ENSSHAP00000020952	ENSSHAP00000007871	Uncharacterized protein.	Ribosomal protein S19.	0.465
EIF2D	RPS21	ENSSHAP00000020952	ENSSHAP00000015968	Uncharacterized protein.	40S ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family.	0.438
EIF2D	RPS24	ENSSHAP00000020952	ENSSHAP00000009353	Uncharacterized protein.	40S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family.	0.438
EIF2D	RPS25	ENSSHAP00000020952	ENSSHAP00000012318	Uncharacterized protein.	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family.	0.454