(42 nodes) Cytosolic small ribosomal subunit network (Sarcophilus harrisii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RPS8	Ribosomal protein S8. (188 aa)
	G3VBL6_SARHA	Uncharacterized protein. (60 aa)
	RPS10	S10_plectin domain-containing protein. (165 aa)
	G3VJ63_SARHA	Uncharacterized protein. (160 aa)
	DHX29	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1341 aa)
	RPS13	Ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family. (155 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (163 aa)
	RPS29	Ribosomal protein S29. (56 aa)
	LOC100924919	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (263 aa)
	RPS4X	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (296 aa)
	G3VVE7_SARHA	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (219 aa)
	G3VVM0_SARHA	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (129 aa)
	SVOPL	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (149 aa)
	RPS19	Ribosomal protein S19. (157 aa)
	RPSA	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...] (295 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	LOC100928280	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (263 aa)
	RPS3A	40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3. (227 aa)
	RPS28	Uncharacterized protein. (45 aa)
	RPS23	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (143 aa)
	G3W2X3_SARHA	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (112 aa)
	G3W5Y0_SARHA	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family. (172 aa)
	RPS12	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (132 aa)
	RPS2	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (293 aa)
	RPS3A-2	40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3. (260 aa)
	RPS21	40S ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family. (83 aa)
	RPS15	Uncharacterized protein; Belongs to the universal ribosomal protein uS19 family. (145 aa)
	RPS7	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (185 aa)
	RPS3	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (242 aa)
	LOC100914101	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (124 aa)
	RPS25	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (119 aa)
	G3W9T5_SARHA	Ribosomal_L7Ae domain-containing protein. (84 aa)
	G3X2K9_SARHA	Uncharacterized protein. (551 aa)
	RPS14	Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family. (157 aa)
	EIF2D	Uncharacterized protein. (583 aa)
	RPS27L	40S ribosomal protein S27. (84 aa)
	EIF2A	Eukaryotic translation initiation factor 2A. (444 aa)
	G3WXD3_SARHA	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (226 aa)
	G3WVD7_SARHA	Uncharacterized protein. (574 aa)
	G3WST0_SARHA	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (125 aa)
	LOC100926189	Uncharacterized protein; Belongs to the universal ribosomal protein uS11 family. (127 aa)
	RPS5	Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (204 aa)

Your Current Organism:

Sarcophilus harrisii

NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DHX29	LOC100926189	ENSSHAP00000003414	ENSSHAP00000000062	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Uncharacterized protein; Belongs to the universal ribosomal protein uS11 family.	0.427
DHX29	RPS13	ENSSHAP00000003414	ENSSHAP00000004611	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family.	0.542
DHX29	RPS14	ENSSHAP00000003414	ENSSHAP00000021298	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	0.423
DHX29	RPS2	ENSSHAP00000003414	ENSSHAP00000017922	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	0.524
DHX29	RPS3A-2	ENSSHAP00000003414	ENSSHAP00000017772	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3.	0.553
DHX29	RPS7	ENSSHAP00000003414	ENSSHAP00000015066	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	0.467
DHX29	RPSA	ENSSHAP00000003414	ENSSHAP00000007949	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...]	0.523
EIF2D	G3W2X3_SARHA	ENSSHAP00000020952	ENSSHAP00000009778	Uncharacterized protein.	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	0.454
EIF2D	G3W5Y0_SARHA	ENSSHAP00000020952	ENSSHAP00000010835	Uncharacterized protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	0.491
EIF2D	LOC100914101	ENSSHAP00000020952	ENSSHAP00000012728	Uncharacterized protein.	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family.	0.454
EIF2D	LOC100924919	ENSSHAP00000020952	ENSSHAP00000006488	Uncharacterized protein.	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family.	0.447
EIF2D	LOC100928280	ENSSHAP00000020952	ENSSHAP00000009327	Uncharacterized protein.	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family.	0.447
EIF2D	RPS10	ENSSHAP00000020952	ENSSHAP00000000819	Uncharacterized protein.	S10_plectin domain-containing protein.	0.450
EIF2D	RPS13	ENSSHAP00000020952	ENSSHAP00000004611	Uncharacterized protein.	Ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family.	0.496
EIF2D	RPS14	ENSSHAP00000020952	ENSSHAP00000021298	Uncharacterized protein.	Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	0.450
EIF2D	RPS15	ENSSHAP00000020952	ENSSHAP00000015754	Uncharacterized protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uS19 family.	0.473
EIF2D	RPS19	ENSSHAP00000020952	ENSSHAP00000007871	Uncharacterized protein.	Ribosomal protein S19.	0.465
EIF2D	RPS21	ENSSHAP00000020952	ENSSHAP00000015968	Uncharacterized protein.	40S ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family.	0.438
EIF2D	RPS25	ENSSHAP00000020952	ENSSHAP00000012318	Uncharacterized protein.	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family.	0.454
EIF2D	RPS27A	ENSSHAP00000020952	ENSSHAP00000005686	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.439