STRINGSTRING
PEAK1 PEAK1 LCP1 LCP1 AJUBA AJUBA DIXDC1 DIXDC1 SORBS1 SORBS1 SDCBP SDCBP CASS4 CASS4 SMPX SMPX TNS3 TNS3 SYNPO2 SYNPO2 TM4SF20 TM4SF20 EPHA2 EPHA2 TNS4 TNS4 SORBS2 SORBS2 ITGA5 ITGA5 ARHGAP26 ARHGAP26 PTK2 PTK2 G3WBW0_SARHA G3WBW0_SARHA MAPK3 MAPK3 ITGB6 ITGB6 ALKBH6 ALKBH6 G3W9V5_SARHA G3W9V5_SARHA ARL14EP ARL14EP WASF1 WASF1 ITGB5 ITGB5 G3W7H1_SARHA G3W7H1_SARHA AVIL AVIL PIK3R2 PIK3R2 FAM107A FAM107A FERMT1 FERMT1 MAPRE2 MAPRE2 ILK ILK VCL VCL RHOU RHOU ASAP3 ASAP3 TLNRD1 TLNRD1 ITGAV ITGAV TRPV4 TRPV4 ACTN3 ACTN3 GAK GAK REXO2 REXO2 PDPK1 PDPK1 MAPK1 MAPK1 IL1RL1 IL1RL1 NEDD9 NEDD9 LIMA1 LIMA1 G3VYD7_SARHA G3VYD7_SARHA G3VY40_SARHA G3VY40_SARHA INPP5E INPP5E ATAT1 ATAT1 G3VXP0_SARHA G3VXP0_SARHA FBLIM1 FBLIM1 ZYX ZYX GIT1 GIT1 SPRY4 SPRY4 G3VVV1_SARHA G3VVV1_SARHA LIMS2 LIMS2 ACTN2 ACTN2 KLF11 KLF11 ITGA11 ITGA11 G3VR75_SARHA G3VR75_SARHA ARHGAP24 ARHGAP24 NOX4 NOX4 NEXN NEXN G3VPT4_SARHA G3VPT4_SARHA G3VPN9_SARHA G3VPN9_SARHA PGM5 PGM5 BCAR3 BCAR3 IL16 IL16 SLC6A4 SLC6A4 SENP1 SENP1 PARVB PARVB PRAG1 PRAG1 LOC100924383 LOC100924383 SYNE2 SYNE2 ARL2 ARL2 VASP VASP LIMS1 LIMS1 ARL14EPL ARL14EPL TNS2 TNS2 PTPRA PTPRA MAP4K4 MAP4K4 CFL1 CFL1 LIMK1 LIMK1 IRF2 IRF2 RSU1 RSU1 ITGBL1 ITGBL1 PTK2B PTK2B ANXA6 ANXA6 TRIP6 TRIP6 UBOX5 UBOX5 USP33 USP33 ITGB7 ITGB7 G3VDC3_SARHA G3VDC3_SARHA MTF2 MTF2 ITGB8 ITGB8 FERMT2 FERMT2 MSN MSN PARVG PARVG ERBIN ERBIN PXN PXN G3VA23_SARHA G3VA23_SARHA FLRT3 FLRT3 SORBS3 SORBS3 TADA1 TADA1 ITGB4 ITGB4 ITGB3 ITGB3 DLC1 DLC1 ITGA6 ITGA6 TNS1 TNS1 SRP68 SRP68 COL17A1 COL17A1 PGM1 PGM1 FOCAD FOCAD DAG1 DAG1 ARPC2 ARPC2 ITGB1 ITGB1 NRAP NRAP ITGA2B ITGA2B TLN2 TLN2 G3WST7_SARHA G3WST7_SARHA PTPRC PTPRC G3WRM6_SARHA G3WRM6_SARHA ZFYVE21 ZFYVE21 CAV1 CAV1 PARVA PARVA CAV2 CAV2 NRP1 NRP1 GRB7 GRB7 G3WQ48_SARHA G3WQ48_SARHA JAK2 JAK2 EFS EFS ATP6V0A2 ATP6V0A2 PALLD PALLD STARD8 STARD8 TLN1 TLN1 PDLIM7 PDLIM7 ARMC5 ARMC5 TGFB1I1 TGFB1I1 SH3KBP1 SH3KBP1 ALOX15B ALOX15B TES TES EPB41L5 EPB41L5 G3WJT6_SARHA G3WJT6_SARHA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PEAK1Pseudopodium enriched atypical kinase 1. (1738 aa)
LCP1Lymphocyte cytosolic protein 1. (632 aa)
AJUBAUncharacterized protein. (193 aa)
DIXDC1DIX domain containing 1. (728 aa)
SORBS1Sorbin and SH3 domain containing 1. (1295 aa)
SDCBPSyndecan binding protein. (298 aa)
CASS4Cas scaffold protein family member 4. (811 aa)
SMPXSmall muscle protein X-linked. (86 aa)
TNS3Tensin 3. (1444 aa)
SYNPO2Synaptopodin 2. (1296 aa)
TM4SF20Transmembrane 4 L six family member 20. (232 aa)
EPHA2EPH receptor A2. (995 aa)
TNS4Tensin 4. (743 aa)
SORBS2Sorbin and SH3 domain containing 2. (1204 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1061 aa)
ARHGAP26Rho GTPase activating protein 26. (714 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1052 aa)
G3WBW0_SARHAVWFA domain-containing protein; Belongs to the integrin alpha chain family. (881 aa)
MAPK3Mitogen-activated protein kinase. (375 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
ALKBH6AlkB homolog 6. (241 aa)
G3W9V5_SARHAUncharacterized protein. (95 aa)
ARL14EPADP ribosylation factor like GTPase 14 effector protein. (258 aa)
WASF1WASP family member 1. (495 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (800 aa)
G3W7H1_SARHAASD2 domain-containing protein. (1238 aa)
AVILAdvillin. (818 aa)
PIK3R2Uncharacterized protein. (738 aa)
FAM107AFamily with sequence similarity 107 member A. (150 aa)
FERMT1Fermitin family member 1. (677 aa)
MAPRE2Microtubule associated protein RP/EB family member 2. (326 aa)
ILKIntegrin linked kinase. (452 aa)
VCLVinculin. (1015 aa)
RHOURas homolog family member U. (152 aa)
ASAP3ArfGAP with SH3 domain, ankyrin repeat and PH domain 3. (860 aa)
TLNRD1Talin rod domain containing 1. (370 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1013 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (743 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (873 aa)
GAKCyclin G associated kinase. (1278 aa)
REXO2RNA exonuclease 2. (234 aa)
PDPK1Protein kinase domain-containing protein. (558 aa)
MAPK1Mitogen-activated protein kinase. (348 aa)
IL1RL1Uncharacterized protein. (537 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (832 aa)
LIMA1LIM domain and actin binding 1. (760 aa)
G3VYD7_SARHASH3 domain-containing protein. (884 aa)
G3VY40_SARHAUncharacterized protein. (141 aa)
INPP5EInositol polyphosphate-5-phosphatase E. (657 aa)
ATAT1Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] (422 aa)
G3VXP0_SARHAARF7EP_C domain-containing protein. (159 aa)
FBLIM1Filamin binding LIM protein 1. (374 aa)
ZYXZyxin. (541 aa)
GIT1GIT ArfGAP 1. (722 aa)
SPRY4Sprouty RTK signaling antagonist 4. (300 aa)
G3VVV1_SARHAULP_PROTEASE domain-containing protein. (272 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (354 aa)
ACTN2Actinin alpha 2. (877 aa)
KLF11Kruppel like factor 11. (521 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1163 aa)
G3VR75_SARHATransporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (566 aa)
ARHGAP24Rho GTPase activating protein 24. (641 aa)
NOX4NADPH oxidase 4. (578 aa)
NEXNNexilin F-actin binding protein. (675 aa)
G3VPT4_SARHACalponin-homology (CH) domain-containing protein. (173 aa)
G3VPN9_SARHAPIPK domain-containing protein. (650 aa)
PGM5Phosphoglucomutase 5; Belongs to the phosphohexose mutase family. (348 aa)
BCAR3BCAR3 adaptor protein, NSP family member. (827 aa)
IL16Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1473 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
SENP1Uncharacterized protein. (455 aa)
PARVBParvin beta. (327 aa)
PRAG1Uncharacterized protein. (789 aa)
LOC100924383FERM domain-containing protein. (378 aa)
SYNE2Spectrin repeat containing nuclear envelope protein 2. (6846 aa)
ARL2Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (184 aa)
VASPVasodilator stimulated phosphoprotein. (382 aa)
LIMS1LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (337 aa)
ARL14EPLARF7EP_C domain-containing protein. (178 aa)
TNS2Tensin 2. (1162 aa)
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (831 aa)
MAP4K4Mitogen-activated protein kinase kinase kinase kinase 4. (1248 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (166 aa)
LIMK1LIM domain kinase 1. (576 aa)
IRF2Interferon regulatory factor. (349 aa)
RSU1Ras suppressor protein 1. (183 aa)
ITGBL1Integrin subunit beta like 1. (347 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1012 aa)
ANXA6Annexin. (672 aa)
TRIP6Thyroid hormone receptor interactor 6. (435 aa)
UBOX5U-box domain containing 5. (540 aa)
USP33Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (906 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (808 aa)
G3VDC3_SARHAIntegrin_alpha2 domain-containing protein. (216 aa)
MTF2PHD-type domain-containing protein. (211 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (726 aa)
FERMT2Fermitin family member 2. (687 aa)
MSNFERM domain-containing protein. (234 aa)
PARVGParvin gamma. (332 aa)
ERBINUncharacterized protein. (361 aa)
PXNPaxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (295 aa)
G3VA23_SARHAProtein kinase domain-containing protein. (353 aa)
FLRT3Fibronectin leucine rich transmembrane protein 3. (649 aa)
SORBS3Sorbin and SH3 domain containing 3. (739 aa)
TADA1Transcriptional adaptor 1. (335 aa)
ITGB4Integrin beta. (1796 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
DLC1DLC1 Rho GTPase activating protein. (1055 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1080 aa)
TNS1Uncharacterized protein. (1515 aa)
SRP68Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (627 aa)
COL17A1Collagen type XVII alpha 1 chain. (1448 aa)
PGM1Phosphoglucomutase 1; Belongs to the phosphohexose mutase family. (579 aa)
FOCADFocadhesin. (1693 aa)
DAG1Dystroglycan 1. (895 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (290 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (799 aa)
NRAPNebulin related anchoring protein. (1766 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1057 aa)
TLN2I/LWEQ domain-containing protein. (2229 aa)
G3WST7_SARHAFERM domain-containing protein. (321 aa)
PTPRCUncharacterized protein. (1311 aa)
G3WRM6_SARHAUncharacterized protein. (282 aa)
ZFYVE21Zinc finger FYVE-type containing 21. (206 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (188 aa)
PARVAParvin alpha. (359 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (857 aa)
GRB7Growth factor receptor bound protein 7. (530 aa)
G3WQ48_SARHAUncharacterized protein. (246 aa)
JAK2Tyrosine-protein kinase. (1137 aa)
EFSEmbryonal Fyn-associated substrate. (565 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (782 aa)
PALLDUncharacterized protein. (452 aa)
STARD8StAR related lipid transfer domain containing 8. (1020 aa)
TLN1Talin 1. (2547 aa)
PDLIM7PDZ and LIM domain 7. (712 aa)
ARMC5Armadillo repeat containing 5. (817 aa)
TGFB1I1Transforming growth factor beta 1 induced transcript 1. (392 aa)
SH3KBP1SH3 domain containing kinase binding protein 1. (614 aa)
ALOX15BArachidonate 15-lipoxygenase type B. (732 aa)
TESTestin LIM domain protein. (421 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (732 aa)
G3WJT6_SARHAUncharacterized protein. (529 aa)
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
Server load: low (30%) [HD]