STRINGSTRING
PDX1 PDX1 FAM214A FAM214A PDIA4 PDIA4 EDEM2 EDEM2 NFE2L2 NFE2L2 G3X2E5_SARHA G3X2E5_SARHA SEL1L2 SEL1L2 UBE4B UBE4B G3W3Z0_SARHA G3W3Z0_SARHA DNAJB12 DNAJB12 HSPA5 HSPA5 OS9 OS9 AMFR AMFR BCAP31 BCAP31 UBE2J2 UBE2J2 SEL1L3 SEL1L3 LOC105750430 LOC105750430 TMTC3 TMTC3 PIK3R2 PIK3R2 EIF2S1 EIF2S1 CREB3L3 CREB3L3 TMUB1 TMUB1 ATF6B ATF6B G3W8D0_SARHA G3W8D0_SARHA THBS4 THBS4 HYOU1 HYOU1 G3W924_SARHA G3W924_SARHA JKAMP JKAMP BCL2L11 BCL2L11 UFD1 UFD1 LOC100930696 LOC100930696 EIF2AK4 EIF2AK4 ATF3 ATF3 FBXO44 FBXO44 CALR3 CALR3 G3WAC2_SARHA G3WAC2_SARHA PML PML STUB1 STUB1 MAN1B1 MAN1B1 PTPN2 PTPN2 XBP1 XBP1 DNAJC18 DNAJC18 P4HB P4HB FICD FICD FOXRED2 FOXRED2 FAF1 FAF1 APAF1 APAF1 MAN1A1 MAN1A1 CANX CANX CREB3L2 CREB3L2 CREB3L4 CREB3L4 SGTA SGTA DERL1 DERL1 UGGT2 UGGT2 PARP16 PARP16 G3WF73_SARHA G3WF73_SARHA DNAJB9 DNAJB9 TMEM259 TMEM259 ERP44 ERP44 GORASP2 GORASP2 TOR1A TOR1A SGTB SGTB G3WGY0_SARHA G3WGY0_SARHA G3WH85_SARHA G3WH85_SARHA CCDC47 CCDC47 ITPR1 ITPR1 MAP3K5 MAP3K5 HERPUD1 HERPUD1 DNAJC3 DNAJC3 UBE4A UBE4A DNAJB2 DNAJB2 GET4 GET4 NPLOC4 NPLOC4 TMTC4 TMTC4 ANKZF1 ANKZF1 TMEM117 TMEM117 UBE2J1 UBE2J1 G3WL94_SARHA G3WL94_SARHA TMEM129 TMEM129 ELAVL4 ELAVL4 RHBDD1 RHBDD1 ATF4 ATF4 ERN1 ERN1 HM13 HM13 CREB3 CREB3 PDIA3 PDIA3 TTC33 TTC33 TMEM33 TMEM33 ERLEC1 ERLEC1 RASGRF2 RASGRF2 QRICH1 QRICH1 CALR CALR NHLRC1 NHLRC1 G3WQU3_SARHA G3WQU3_SARHA UFL1 UFL1 USP19 USP19 CREB3L1 CREB3L1 G3WRD8_SARHA G3WRD8_SARHA TMUB2 TMUB2 UBA5 UBA5 TMEM67 TMEM67 TP53 TP53 STT3B STT3B BHLHA15 BHLHA15 TBL2 TBL2 CXCL8 CXCL8 AIFM1 AIFM1 VAPB VAPB SELENOK SELENOK G3WUN9_SARHA G3WUN9_SARHA SCAMP5 SCAMP5 CHAC1 CHAC1 ERLIN2 ERLIN2 UFC1 UFC1 FAM214B FAM214B TMCO1 TMCO1 VCP VCP WFS1 WFS1 AUP1 AUP1 UBXN4 UBXN4 USP13 USP13 RNF183 RNF183 BCL2 BCL2 ATG10 ATG10 DAB2IP DAB2IP FBXO27 FBXO27 PIK3R1 PIK3R1 FLOT1 FLOT1 NCK2 NCK2 DDIT3 DDIT3 G3VYH5_SARHA G3VYH5_SARHA RNF139 RNF139 G3VXF2_SARHA G3VXF2_SARHA EIF2AK3 EIF2AK3 EP300 EP300 UGGT1 UGGT1 CDK5RAP3 CDK5RAP3 NCK1 NCK1 HERPUD2 HERPUD2 G3VVU2_SARHA G3VVU2_SARHA SELENOS SELENOS PRKN PRKN NRBF2 NRBF2 SESN2 SESN2 CERT1 CERT1 BAK1 BAK1 TRIB3 TRIB3 NIBAN1 NIBAN1 BAG6 BAG6 EDEM1 EDEM1 DNAJB14 DNAJB14 ERN2 ERN2 THBS1 THBS1 RNF121 RNF121 G3VU94_SARHA G3VU94_SARHA UBXN6 UBXN6 ANKS4B ANKS4B MARCHF6 MARCHF6 NCCRP1 NCCRP1 RASGRF1 RASGRF1 SYVN1 SYVN1 EIF2B5 EIF2B5 LOC100932741 LOC100932741 HSP90B1 HSP90B1 EIF2AK2 EIF2AK2 CLGN CLGN SRPX SRPX ERLIN1 ERLIN1 UBE2G2 UBE2G2 SEL1L SEL1L CCND1 CCND1 EDEM3 EDEM3 PDIA2 PDIA2 DDRGK1 DDRGK1 TMX1 TMX1 DNAJC10 DNAJC10 FAF2 FAF2 RNF185 RNF185 ECPAS ECPAS G3VPS2_SARHA G3VPS2_SARHA ERMP1 ERMP1 RCN3 RCN3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDX1Homeobox domain-containing protein. (287 aa)
FAM214AFamily with sequence similarity 214 member A. (1087 aa)
PDIA4Protein disulfide-isomerase A4. (645 aa)
EDEM2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (579 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (598 aa)
G3X2E5_SARHAOTU domain-containing protein. (264 aa)
SEL1L2SEL1L2 adaptor subunit of ERAD E3 ligase. (676 aa)
UBE4BUbiquitination factor E4B. (1114 aa)
G3W3Z0_SARHAUBX domain-containing protein. (261 aa)
DNAJB12DnaJ heat shock protein family (Hsp40) member B12. (346 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (656 aa)
OS9OS9 endoplasmic reticulum lectin. (674 aa)
AMFRAutocrine motility factor receptor. (620 aa)
BCAP31Uncharacterized protein. (239 aa)
UBE2J2Ubiquitin conjugating enzyme E2 J2. (260 aa)
SEL1L3SEL1L family member 3. (1088 aa)
LOC105750430Rhomboid domain-containing protein. (195 aa)
TMTC3Transmembrane O-mannosyltransferase targeting cadherins 3. (918 aa)
PIK3R2Uncharacterized protein. (738 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (465 aa)
TMUB1Transmembrane and ubiquitin like domain containing 1. (248 aa)
ATF6BActivating transcription factor 6 beta. (709 aa)
G3W8D0_SARHAUncharacterized protein. (183 aa)
THBS4Thrombospondin 4. (956 aa)
HYOU1Hypoxia up-regulated 1. (1016 aa)
G3W924_SARHAUncharacterized protein. (270 aa)
JKAMPJNK1/MAPK8 associated membrane protein. (324 aa)
BCL2L11BCL2 like 11. (200 aa)
UFD1Ubiquitin recognition factor in ER associated degradation 1. (307 aa)
LOC100930696Uncharacterized protein. (288 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1598 aa)
ATF3Activating transcription factor 3. (181 aa)
FBXO44Uncharacterized protein. (254 aa)
CALR3Calreticulin 3. (388 aa)
G3WAC2_SARHAUncharacterized protein. (250 aa)
PMLUncharacterized protein. (376 aa)
STUB1STIP1 homology and U-box containing protein 1. (256 aa)
MAN1B1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (625 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (420 aa)
XBP1BZIP domain-containing protein. (308 aa)
DNAJC18DnaJ heat shock protein family (Hsp40) member C18. (361 aa)
P4HBProtein disulfide-isomerase. (510 aa)
FICDFIC domain containing. (453 aa)
FOXRED2FAD dependent oxidoreductase domain containing 2. (516 aa)
FAF1Fas associated factor 1. (550 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1255 aa)
MAN1A1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (359 aa)
CANXCalnexin. (601 aa)
CREB3L2BZIP domain-containing protein. (517 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (389 aa)
SGTATPR_REGION domain-containing protein. (315 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (252 aa)
UGGT2UDP-glucose glycoprotein glucosyltransferase 2. (1478 aa)
PARP16Poly [ADP-ribose] polymerase. (325 aa)
G3WF73_SARHAPeptidase_M50 domain-containing protein. (314 aa)
DNAJB9DnaJ heat shock protein family (Hsp40) member B9. (219 aa)
TMEM259Uncharacterized protein. (321 aa)
ERP44Endoplasmic reticulum protein 44. (406 aa)
GORASP2Golgi reassembly stacking protein 2. (429 aa)
TOR1ATorsin. (333 aa)
SGTBSmall glutamine rich tetratricopeptide repeat containing beta. (304 aa)
G3WGY0_SARHATPR_REGION domain-containing protein. (349 aa)
G3WH85_SARHARING-type domain-containing protein. (497 aa)
CCDC47Coiled-coil domain containing 47. (484 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2696 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1385 aa)
HERPUD1Homocysteine inducible ER protein with ubiquitin like domain 1. (475 aa)
DNAJC3DnaJ heat shock protein family (Hsp40) member C3. (509 aa)
UBE4AUbiquitination factor E4A. (1068 aa)
DNAJB2DnaJ heat shock protein family (Hsp40) member B2. (324 aa)
GET4Guided entry of tail-anchored proteins factor 4. (327 aa)
NPLOC4NPL4 homolog, ubiquitin recognition factor. (616 aa)
TMTC4Transmembrane O-mannosyltransferase targeting cadherins 4. (740 aa)
ANKZF1Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1. (617 aa)
TMEM117Transmembrane protein 117. (517 aa)
UBE2J1Ubiquitin conjugating enzyme E2 J1. (320 aa)
G3WL94_SARHAUncharacterized protein. (1322 aa)
TMEM129Transmembrane protein 129. (298 aa)
ELAVL4ELAV-like protein; Belongs to the RRM elav family. (371 aa)
RHBDD1Rhomboid domain containing 1. (285 aa)
ATF4Activating transcription factor 4. (344 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (922 aa)
HM13Histocompatibility minor 13. (385 aa)
CREB3BZIP domain-containing protein. (370 aa)
PDIA3Protein disulfide-isomerase. (506 aa)
TTC33Tetratricopeptide repeat domain 33. (262 aa)
TMEM33Transmembrane protein 33. (247 aa)
ERLEC1Endoplasmic reticulum lectin 1. (482 aa)
RASGRF2Ras protein specific guanine nucleotide releasing factor 2. (1137 aa)
QRICH1Glutamine rich 1. (776 aa)
CALRCalreticulin. (418 aa)
NHLRC1NHL repeat containing E3 ubiquitin protein ligase 1. (404 aa)
G3WQU3_SARHABap31 domain-containing protein. (216 aa)
UFL1UFM1 specific ligase 1. (794 aa)
USP19Ubiquitin specific peptidase 19. (1444 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (526 aa)
G3WRD8_SARHAOTU domain-containing protein. (354 aa)
TMUB2Transmembrane and ubiquitin like domain containing 2. (316 aa)
UBA5Ubiquitin like modifier activating enzyme 5. (409 aa)
TMEM67Transmembrane protein 67. (897 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (371 aa)
STT3BSTT3 oligosaccharyltransferase complex catalytic subunit B. (740 aa)
BHLHA15Basic helix-loop-helix family member a15. (175 aa)
TBL2Transducin beta like 2. (496 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (103 aa)
AIFM1Apoptosis inducing factor mitochondria associated 1. (580 aa)
VAPBVAMP associated protein B and C. (240 aa)
SELENOKSelenoprotein K. (90 aa)
G3WUN9_SARHAUncharacterized protein. (150 aa)
SCAMP5Secretory carrier-associated membrane protein. (235 aa)
CHAC1Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (175 aa)
ERLIN2ER lipid raft associated 2. (338 aa)
UFC1Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage. (167 aa)
FAM214BFamily with sequence similarity 214 member B. (537 aa)
TMCO1Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling; Belongs to the TMCO1 family. (188 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (802 aa)
WFS1Wolframin ER transmembrane glycoprotein. (872 aa)
AUP1AUP1 lipid droplet regulating VLDL assembly factor. (298 aa)
UBXN4UBX domain-containing protein. (517 aa)
USP13Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (798 aa)
RNF183Ring finger protein 183. (190 aa)
BCL2BCL2 apoptosis regulator. (227 aa)
ATG10Autophagy related 10. (226 aa)
DAB2IPDAB2 interacting protein. (783 aa)
FBXO27Uncharacterized protein. (285 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
NCK2Cytoplasmic protein. (380 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (170 aa)
G3VYH5_SARHAUncharacterized protein. (478 aa)
RNF139Ring finger protein 139. (669 aa)
G3VXF2_SARHACalreticulin. (419 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1081 aa)
EP300E1A binding protein p300. (1895 aa)
UGGT1Glyco_transf_24 domain-containing protein. (112 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (506 aa)
NCK1Cytoplasmic protein. (377 aa)
HERPUD2HERPUD family member 2. (355 aa)
G3VVU2_SARHAAAA domain-containing protein; Belongs to the AAA ATPase family. (389 aa)
SELENOSSelenoprotein S. (193 aa)
PRKNUbiquitin-like domain-containing protein. (54 aa)
NRBF2Nuclear receptor binding factor 2. (280 aa)
SESN2Sestrin 2. (473 aa)
CERT1Ceramide transporter 1. (511 aa)
BAK1BCL2 antagonist/killer 1. (208 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
NIBAN1Niban apoptosis regulator 1. (940 aa)
BAG6BCL2 associated athanogene 6. (1131 aa)
EDEM1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (595 aa)
DNAJB14DnaJ heat shock protein family (Hsp40) member B14. (385 aa)
ERN2Endoplasmic reticulum to nucleus signaling 2. (900 aa)
THBS1Thrombospondin 1. (1180 aa)
RNF121Ring finger protein 121. (326 aa)
G3VU94_SARHABZIP domain-containing protein. (465 aa)
UBXN6PUB domain-containing protein. (125 aa)
ANKS4BAnkyrin repeat and sterile alpha motif domain containing 4B. (349 aa)
MARCHF6Membrane associated ring-CH-type finger 6. (812 aa)
NCCRP1FBA domain-containing protein. (165 aa)
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1257 aa)
SYVN1Synoviolin 1. (520 aa)
EIF2B5Eukaryotic translation initiation factor 2B subunit epsilon. (663 aa)
LOC100932741GOLD domain-containing protein. (178 aa)
HSP90B1Heat shock protein 90 beta family member 1. (803 aa)
EIF2AK2Uncharacterized protein. (563 aa)
CLGNUncharacterized protein. (608 aa)
SRPXSushi repeat containing protein X-linked. (455 aa)
ERLIN1ER lipid raft associated 1. (353 aa)
UBE2G2Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (167 aa)
SEL1LSEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (761 aa)
CCND1Cyclin_C domain-containing protein. (141 aa)
EDEM3alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (905 aa)
PDIA2Protein disulfide isomerase family A member 2. (606 aa)
DDRGK1Uncharacterized protein. (251 aa)
TMX1Thioredoxin related transmembrane protein 1. (224 aa)
DNAJC10DnaJ heat shock protein family (Hsp40) member C10. (800 aa)
FAF2Fas associated factor family member 2. (372 aa)
RNF185Ring finger protein 185. (195 aa)
ECPASEcm29 proteasome adaptor and scaffold. (1847 aa)
G3VPS2_SARHAPP1c_bdg domain-containing protein. (199 aa)
ERMP1Endoplasmic reticulum metallopeptidase 1. (807 aa)
RCN3Reticulocalbin 3. (308 aa)
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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