(14 nodes) Ciliary rootlet network (Sarcophilus harrisii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KLC3	Kinesin light chain 3. (498 aa)
	APP	Amyloid beta precursor protein. (750 aa)
	CCDC151	Uncharacterized protein. (563 aa)
	KIF5B	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (928 aa)
	KIF5A	Kinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1032 aa)
	RPGRIP1L	RPGRIP1 like. (1268 aa)
	G3W3I9_SARHA	Uncharacterized protein. (1325 aa)
	RAB28	Uncharacterized protein. (204 aa)
	PSEN2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (462 aa)
	PJVK	Pejvakin. (354 aa)
	CROCC2	Uncharacterized protein. (1805 aa)
	KIF5C	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (921 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (470 aa)
	SPAG5	Uncharacterized protein. (1151 aa)

Your Current Organism:

Sarcophilus harrisii

NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APP	KLC3	ENSSHAP00000002408	ENSSHAP00000001898	Amyloid beta precursor protein.	Kinesin light chain 3.	0.629
APP	PSEN1	ENSSHAP00000002408	ENSSHAP00000014543	Amyloid beta precursor protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.950
APP	PSEN2	ENSSHAP00000002408	ENSSHAP00000011643	Amyloid beta precursor protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.874
G3W3I9_SARHA	SPAG5	ENSSHAP00000009994	ENSSHAP00000016460	Uncharacterized protein.	Uncharacterized protein.	0.423
KIF5A	KIF5B	ENSSHAP00000008863	ENSSHAP00000007188	Kinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.954
KIF5A	KIF5C	ENSSHAP00000008863	ENSSHAP00000012050	Kinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.403
KIF5A	KLC3	ENSSHAP00000008863	ENSSHAP00000001898	Kinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin light chain 3.	0.813
KIF5B	KIF5A	ENSSHAP00000007188	ENSSHAP00000008863	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.954
KIF5B	KLC3	ENSSHAP00000007188	ENSSHAP00000001898	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin light chain 3.	0.860
KIF5C	KIF5A	ENSSHAP00000012050	ENSSHAP00000008863	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.403
KIF5C	KLC3	ENSSHAP00000012050	ENSSHAP00000001898	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin light chain 3.	0.746
KLC3	APP	ENSSHAP00000001898	ENSSHAP00000002408	Kinesin light chain 3.	Amyloid beta precursor protein.	0.629
KLC3	KIF5A	ENSSHAP00000001898	ENSSHAP00000008863	Kinesin light chain 3.	Kinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.813
KLC3	KIF5B	ENSSHAP00000001898	ENSSHAP00000007188	Kinesin light chain 3.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.860
KLC3	KIF5C	ENSSHAP00000001898	ENSSHAP00000012050	Kinesin light chain 3.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.746
PSEN1	APP	ENSSHAP00000014543	ENSSHAP00000002408	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Amyloid beta precursor protein.	0.950
PSEN1	PSEN2	ENSSHAP00000014543	ENSSHAP00000011643	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.998
PSEN2	APP	ENSSHAP00000011643	ENSSHAP00000002408	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Amyloid beta precursor protein.	0.874
PSEN2	PSEN1	ENSSHAP00000011643	ENSSHAP00000014543	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.998
SPAG5	G3W3I9_SARHA	ENSSHAP00000016460	ENSSHAP00000009994	Uncharacterized protein.	Uncharacterized protein.	0.423