STRINGSTRING
CRKL CRKL BMP4 BMP4 PCSK1 PCSK1 CDK6 CDK6 RFX3 RFX3 NKX2-2 NKX2-2 NR0B1 NR0B1 HNF1B HNF1B BAK1 BAK1 G3VSB8_SARHA G3VSB8_SARHA PITX2 PITX2 BMPR1A BMPR1A CITED2 CITED2 GLI1 GLI1 EIF2AK3 EIF2AK3 GATA6 GATA6 EDNRA EDNRA MAPK1 MAPK1 PDPK1 PDPK1 POU1F1 POU1F1 SMO SMO NKX2-5 NKX2-5 GDF11 GDF11 RFX6 RFX6 SALL1 SALL1 ANXA1 ANXA1 WNT11 WNT11 FGF2 FGF2 GCM2 GCM2 MAPK3 MAPK3 LHX3 LHX3 STRA6 STRA6 PAX8 PAX8 ALDH1A2 ALDH1A2 ARID5B ARID5B HOXB3 HOXB3 BMP2 BMP2 HESX1 HESX1 SRF SRF BMP6 BMP6 PDGFRA PDGFRA DKK3 DKK3 TG TG PITX1 PITX1 THRA THRA IL6R IL6R CREB1 CREB1 ARMC5 ARMC5 GIP GIP DLL1 DLL1 DRD2 DRD2 FOXA2 FOXA2 NKX6-1 NKX6-1 EDN1 EDN1 PAX4 PAX4 BRAF BRAF HOXD3 HOXD3 GATA2 GATA2 WNT4 WNT4 SLC6A3 SLC6A3 PAX6 PAX6 TGFBR1 TGFBR1 HOXA5 HOXA5 HOXA3 HOXA3 GHRH GHRH WT1 WT1 CYP1B1 CYP1B1 PAX1 PAX1 GSX1 GSX1 PDX1 PDX1 MNX1 MNX1 OTP OTP GATA3 GATA3 NF1 NF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CRKLCRK like proto-oncogene, adaptor protein. (194 aa)
BMP4Bone morphogenetic protein 4. (410 aa)
PCSK1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (752 aa)
CDK6Cyclin dependent kinase 6. (202 aa)
RFX3Regulatory factor X3. (752 aa)
NKX2-2NK2 homeobox 2. (273 aa)
NR0B1NR LBD domain-containing protein. (208 aa)
HNF1BHNF1 homeobox B. (558 aa)
BAK1BCL2 antagonist/killer 1. (208 aa)
G3VSB8_SARHAHomeobox domain-containing protein. (216 aa)
PITX2Homeobox protein. (330 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (246 aa)
GLI1GLI family zinc finger 1. (1097 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1081 aa)
GATA6GATA binding protein 6. (462 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
MAPK1Mitogen-activated protein kinase. (348 aa)
PDPK1Protein kinase domain-containing protein. (558 aa)
POU1F1POU domain protein. (318 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (759 aa)
NKX2-5Homeobox domain-containing protein. (320 aa)
GDF11Growth differentiation factor 11. (386 aa)
RFX6Regulatory factor X6. (929 aa)
SALL1Spalt like transcription factor 1. (1307 aa)
ANXA1Annexin. (346 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (203 aa)
GCM2Glial cells missing transcription factor 2. (486 aa)
MAPK3Mitogen-activated protein kinase. (375 aa)
LHX3LIM homeobox 3. (403 aa)
STRA6Uncharacterized protein. (487 aa)
PAX8Paired box 8. (457 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa)
ARID5BAT-rich interaction domain 5B. (994 aa)
HOXB3Homeobox B3. (426 aa)
BMP2Bone morphogenetic protein 2. (394 aa)
HESX1HESX homeobox 1. (189 aa)
SRFSerum response factor. (306 aa)
BMP6Bone morphogenetic protein 6. (439 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1101 aa)
DKK3Dickkopf WNT signaling pathway inhibitor 3. (377 aa)
TGThyroglobulin. (2428 aa)
PITX1Homeobox protein. (306 aa)
THRAThyroid hormone receptor alpha. (408 aa)
IL6RUncharacterized protein. (468 aa)
CREB1cAMP responsive element binding protein 1. (327 aa)
ARMC5Armadillo repeat containing 5. (817 aa)
GIPGLUCAGON domain-containing protein. (78 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (733 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (454 aa)
FOXA2Forkhead box A2. (460 aa)
NKX6-1NK6 homeobox 1. (379 aa)
EDN1Endothelin 1. (214 aa)
PAX4Paired box 4. (296 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (716 aa)
HOXD3Homeobox D3. (430 aa)
GATA2GATA binding protein 2. (398 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (264 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (619 aa)
PAX6Paired box 6. (436 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (475 aa)
HOXA5Homeobox A5. (271 aa)
HOXA3Homeobox A3. (443 aa)
GHRHGLUCAGON domain-containing protein. (170 aa)
WT1WT1 transcription factor. (399 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (545 aa)
PAX1Paired box 1. (453 aa)
GSX1GS homeobox 1. (262 aa)
PDX1Homeobox domain-containing protein. (287 aa)
MNX1Motor neuron and pancreas homeobox 1. (363 aa)
OTPOrthopedia homeobox. (325 aa)
GATA3GATA binding protein 3. (444 aa)
NF1Neurofibromin 1. (2775 aa)
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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