STRINGSTRING
IMPACT IMPACT G3VA16_SARHA G3VA16_SARHA HSF1 HSF1 TIRAP TIRAP CDT1 CDT1 MSN MSN FERMT2 FERMT2 G3VCH7_SARHA G3VCH7_SARHA CYRIA CYRIA ARFGEF1 ARFGEF1 ARF6 ARF6 FCHSD2 FCHSD2 TPPP2 TPPP2 G3VDB1_SARHA G3VDB1_SARHA G3VDG2_SARHA G3VDG2_SARHA G3VDJ5_SARHA G3VDJ5_SARHA ZNF827 ZNF827 LCMT1 LCMT1 ELN ELN CAMSAP1 CAMSAP1 CAMSAP2 CAMSAP2 APOE APOE G3VEA0_SARHA G3VEA0_SARHA EIF2AK2 EIF2AK2 SYK SYK CLUL1 CLUL1 G3VEX3_SARHA G3VEX3_SARHA MKKS MKKS BBS10 BBS10 PLEK PLEK PTK2B PTK2B PARP1 PARP1 EML2 EML2 G3VGL6_SARHA G3VGL6_SARHA SCIN SCIN G3VH30_SARHA G3VH30_SARHA NOP53 NOP53 FLII FLII G3VHX7_SARHA G3VHX7_SARHA WNT10B WNT10B SH3GLB1 SH3GLB1 DHX33 DHX33 G3VJ63_SARHA G3VJ63_SARHA MAPK15 MAPK15 TWF2 TWF2 VASP VASP ARL2 ARL2 G3VL00_SARHA G3VL00_SARHA DBNL DBNL FER FER G3VL49_SARHA G3VL49_SARHA PYCARD PYCARD LOC100924383 LOC100924383 COTL1 COTL1 BAIAP2 BAIAP2 FNIP1 FNIP1 LGALS3 LGALS3 CAPG CAPG G3VPT4_SARHA G3VPT4_SARHA TPPP TPPP PAK3 PAK3 G3VR90_SARHA G3VR90_SARHA NUMA1 NUMA1 BAK1 BAK1 G3VRW8_SARHA G3VRW8_SARHA SLAIN1 SLAIN1 RPL13A RPL13A TBCD TBCD G3VSN1_SARHA G3VSN1_SARHA MAPK9 MAPK9 CPTP CPTP TOGARAM1 TOGARAM1 STXBP6 STXBP6 CAPZB CAPZB CYFIP1 CYFIP1 ANKRD27 ANKRD27 PFN1 PFN1 KANK1 KANK1 TFRC TFRC G3VUW4_SARHA G3VUW4_SARHA PTPN11 PTPN11 PAK1 PAK1 TGFB1 TGFB1 G3VVU2_SARHA G3VVU2_SARHA STMN1 STMN1 NCK1 NCK1 ADD2 ADD2 GIT1 GIT1 CDC42EP3 CDC42EP3 EP300 EP300 FBLIM1 FBLIM1 SOST SOST ATAT1 ATAT1 G3VXY1_SARHA G3VXY1_SARHA CLU CLU G3VYH8_SARHA G3VYH8_SARHA BAIAP2L2 BAIAP2L2 NCLN NCLN NCK2 NCK2 CXCL13 CXCL13 G3W0N3_SARHA G3W0N3_SARHA LCAT LCAT MECP2 MECP2 NCKAP1 NCKAP1 GBA GBA SMAD6 SMAD6 RNF4 RNF4 KANK3 KANK3 CLDN7 CLDN7 DAB2IP DAB2IP PINK1 PINK1 MYADM MYADM MAP2 MAP2 PRKCD PRKCD G3W342_SARHA G3W342_SARHA SAR1A SAR1A KIRREL1 KIRREL1 ABITRAM ABITRAM AIDA AIDA HSPA5 HSPA5 SKAP1 SKAP1 NAPB NAPB CALY CALY BID BID TRAF3IP1 TRAF3IP1 ARHGAP28 ARHGAP28 CLIP1 CLIP1 FES FES PRRT2 PRRT2 FERMT1 FERMT1 SLF1 SLF1 KIF9 KIF9 PIK3R2 PIK3R2 LMOD2 LMOD2 AVIL AVIL SPTA1 SPTA1 G3W8M0_SARHA G3W8M0_SARHA G3W8Q5_SARHA G3W8Q5_SARHA SPTBN1 SPTBN1 BCL2L11 BCL2L11 CARMIL1 CARMIL1 TRABD2A TRABD2A OPRD1 OPRD1 MAP1B MAP1B ARPC1A ARPC1A TAL1 TAL1 STUB1 STUB1 IL5 IL5 HCLS1 HCLS1 LMOD1 LMOD1 ATM ATM STX1B STX1B FCHSD1 FCHSD1 CORO1A CORO1A CTNNBIP1 CTNNBIP1 FAF1 FAF1 RPS3 RPS3 RICTOR RICTOR PMEPA1 PMEPA1 TRABD2B TRABD2B SENP6 SENP6 BMF BMF ADD1 ADD1 PLCG2 PLCG2 DNAJC15 DNAJC15 MAPRE3 MAPRE3 SVIL SVIL SLC39A12 SLC39A12 RIOK3 RIOK3 SPTB SPTB NCKAP1L NCKAP1L DYRK1A DYRK1A MYD88 MYD88 FNIP2 FNIP2 PREB PREB SEPTIN8 SEPTIN8 USP50 USP50 SSH1 SSH1 ARHGEF5 ARHGEF5 MPP7 MPP7 JAM3 JAM3 HIP1R HIP1R RACK1 RACK1 MTOR MTOR DRG1 DRG1 TTBK1 TTBK1 HAX1 HAX1 FARP2 FARP2 FAM49B FAM49B AJUBA AJUBA ANKRA2 ANKRA2 LCP1 LCP1 ULK1 ULK1 CRYAB CRYAB THRA THRA ARPC5 ARPC5 TRAPPC12 TRAPPC12 TMOD4 TMOD4 WARS1 WARS1 CSF3 CSF3 TFIP11 TFIP11 EPS8 EPS8 ASAP1 ASAP1 GBA2 GBA2 TWF1 TWF1 DBN1 DBN1 KIF14 KIF14 G3WND9_SARHA G3WND9_SARHA PPM1A PPM1A PTGER4 PTGER4 SPIDR SPIDR ARPC3 ARPC3 G3WQ48_SARHA G3WQ48_SARHA SAR1B SAR1B IFNG IFNG DKK1 DKK1 LDLRAD4 LDLRAD4 NLRC3 NLRC3 ESAM ESAM SORL1 SORL1 ESR1 ESR1 G3WRI4_SARHA G3WRI4_SARHA EVL EVL TMOD1 TMOD1 ARPC4 ARPC4 TP53 TP53 VEGFA VEGFA CDC42EP4 CDC42EP4 MTPN MTPN AMBRA1 AMBRA1 ATR ATR MET MET ADD3 ADD3 PARK7 PARK7 CYFIP2 CYFIP2 G3WU11_SARHA G3WU11_SARHA VIL1 VIL1 BAIAP2L1 BAIAP2L1 STX1A STX1A TBX20 TBX20 BBS4 BBS4 CKAP5 CKAP5 CDC42EP1 CDC42EP1 G3WV84_SARHA G3WV84_SARHA CAPZA2 CAPZA2 ARHGAP40 ARHGAP40 CDH17 CDH17 LMOD3 LMOD3 TMOD2 TMOD2 ARPC2 ARPC2 VCP VCP TMOD3 TMOD3 ARHGAP18 ARHGAP18 PDE4DIP PDE4DIP RASA1 RASA1 MLST8 MLST8 MAPT MAPT PEX5 PEX5 DCTN1 DCTN1 TENM1 TENM1 TLR4 TLR4 CCL21 CCL21 BAG4 BAG4 LATS1 LATS1 CDH5 CDH5 ATF7IP ATF7IP IKBKE IKBKE GSN GSN DMTN DMTN PSRC1 PSRC1 STMN2 STMN2 TMC8 TMC8 SLIT2 SLIT2 G3X1T9_SARHA G3X1T9_SARHA GRB2 GRB2 DACT1 DACT1 SLAIN2 SLAIN2 KANK4 KANK4 ICE1 ICE1 SPTAN1 SPTAN1 SNX9 SNX9 PFN2 PFN2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IMPACTImpact RWD domain protein. (320 aa)
G3VA16_SARHAPH domain-containing protein. (788 aa)
HSF1Heat shock transcription factor 1. (446 aa)
TIRAPTIR domain containing adaptor protein. (218 aa)
CDT1Chromatin licensing and DNA replication factor 1. (422 aa)
MSNFERM domain-containing protein. (234 aa)
FERMT2Fermitin family member 2. (687 aa)
G3VCH7_SARHAUncharacterized protein. (156 aa)
CYRIAUncharacterized protein. (275 aa)
ARFGEF1ADP ribosylation factor guanine nucleotide exchange factor 1. (1829 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (187 aa)
FCHSD2Uncharacterized protein. (616 aa)
TPPP2Tubulin polymerization promoting protein family member 2. (168 aa)
G3VDB1_SARHAUBP-type domain-containing protein. (1054 aa)
G3VDG2_SARHAUncharacterized protein. (490 aa)
G3VDJ5_SARHAUncharacterized protein. (109 aa)
ZNF827Uncharacterized protein. (289 aa)
LCMT1Uncharacterized protein. (173 aa)
ELNUncharacterized protein. (578 aa)
CAMSAP1Calmodulin regulated spectrin associated protein 1. (1614 aa)
CAMSAP2Calmodulin regulated spectrin associated protein family member 2. (1271 aa)
APOEUncharacterized protein. (256 aa)
G3VEA0_SARHAUncharacterized protein. (110 aa)
EIF2AK2Uncharacterized protein. (563 aa)
SYKTyrosine-protein kinase. (466 aa)
CLUL1Clusterin; Belongs to the clusterin family. (473 aa)
G3VEX3_SARHAUncharacterized protein. (106 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
BBS10Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (799 aa)
PLEKPleckstrin. (350 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1012 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (972 aa)
EML2EMAP like 2. (725 aa)
G3VGL6_SARHAIPPc domain-containing protein. (697 aa)
SCINScinderin. (646 aa)
G3VH30_SARHAUncharacterized protein. (258 aa)
NOP53Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (411 aa)
FLIIFLII actin remodeling protein. (992 aa)
G3VHX7_SARHAUncharacterized protein. (495 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
SH3GLB1SH3 domain containing GRB2 like, endophilin B1. (368 aa)
DHX33DEAH-box helicase 33. (726 aa)
G3VJ63_SARHAUncharacterized protein. (160 aa)
MAPK15Mitogen-activated protein kinase. (564 aa)
TWF2Twinfilin actin binding protein 2. (343 aa)
VASPVasodilator stimulated phosphoprotein. (382 aa)
ARL2Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (184 aa)
G3VL00_SARHAUncharacterized protein. (503 aa)
DBNLDrebrin like. (430 aa)
FERProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (272 aa)
G3VL49_SARHAANK_REP_REGION domain-containing protein. (385 aa)
PYCARDUncharacterized protein. (200 aa)
LOC100924383FERM domain-containing protein. (378 aa)
COTL1Coactosin like F-actin binding protein 1. (142 aa)
BAIAP2BAI1 associated protein 2. (503 aa)
FNIP1Folliculin interacting protein 1. (1114 aa)
LGALS3Galectin. (273 aa)
CAPGCapping actin protein, gelsolin like. (351 aa)
G3VPT4_SARHACalponin-homology (CH) domain-containing protein. (173 aa)
TPPPTubulin polymerization promoting protein. (218 aa)
PAK3Non-specific serine/threonine protein kinase. (544 aa)
G3VR90_SARHADUF4502 domain-containing protein. (194 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2096 aa)
BAK1BCL2 antagonist/killer 1. (208 aa)
G3VRW8_SARHADUF4592 domain-containing protein. (1065 aa)
SLAIN1SLAIN motif family member 1. (509 aa)
RPL13ARibosomal protein L13a. (118 aa)
TBCDTFCD_C domain-containing protein. (325 aa)
G3VSN1_SARHADilute domain-containing protein. (602 aa)
MAPK9Mitogen-activated protein kinase. (429 aa)
CPTPCeramide-1-phosphate transfer protein. (217 aa)
TOGARAM1TOG array regulator of axonemal microtubules 1. (1833 aa)
STXBP6Syntaxin binding protein 6. (210 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (274 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1265 aa)
ANKRD27Ankyrin repeat domain 27. (1023 aa)
PFN1Profilin; Belongs to the profilin family. (140 aa)
KANK1KN motif and ankyrin repeat domains 1. (1343 aa)
TFRCTransferrin receptor. (770 aa)
G3VUW4_SARHATelomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (369 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (602 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
TGFB1TGF_BETA_2 domain-containing protein. (162 aa)
G3VVU2_SARHAAAA domain-containing protein; Belongs to the AAA ATPase family. (389 aa)
STMN1Stathmin; Belongs to the stathmin family. (180 aa)
NCK1Cytoplasmic protein. (377 aa)
ADD2Adducin 2. (730 aa)
GIT1GIT ArfGAP 1. (722 aa)
CDC42EP3CDC42 effector protein 3. (255 aa)
EP300E1A binding protein p300. (1895 aa)
FBLIM1Filamin binding LIM protein 1. (374 aa)
SOSTSclerostin. (212 aa)
ATAT1Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] (422 aa)
G3VXY1_SARHAUncharacterized protein. (2099 aa)
CLUClusterin; Belongs to the clusterin family. (405 aa)
G3VYH8_SARHADUF4502 domain-containing protein. (182 aa)
BAIAP2L2BAI1 associated protein 2 like 2. (539 aa)
NCLNNicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. (552 aa)
NCK2Cytoplasmic protein. (380 aa)
CXCL13SCY domain-containing protein. (104 aa)
G3W0N3_SARHAUncharacterized protein. (1571 aa)
LCATLecithin-cholesterol acyltransferase. (446 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (492 aa)
NCKAP1NCK associated protein 1. (1055 aa)
GBAGlucosylceramidase. (536 aa)
SMAD6Mothers against decapentaplegic homolog. (367 aa)
RNF4Ring finger protein 4. (194 aa)
KANK3ANK_REP_REGION domain-containing protein. (829 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
DAB2IPDAB2 interacting protein. (783 aa)
PINK1PTEN induced kinase 1. (453 aa)
MYADMMyeloid associated differentiation marker. (321 aa)
MAP2Microtubule-associated protein. (1790 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (677 aa)
G3W342_SARHAUncharacterized protein. (69 aa)
SAR1ASecretion associated Ras related GTPase 1A; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
KIRREL1Kirre like nephrin family adhesion molecule 1. (842 aa)
ABITRAMActin binding transcription modulator. (157 aa)
AIDAAxin interactor, dorsalization associated. (247 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (656 aa)
SKAP1Src kinase associated phosphoprotein 1. (281 aa)
NAPBNSF attachment protein beta. (299 aa)
CALYUncharacterized protein. (193 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (194 aa)
TRAF3IP1TRAF3 interacting protein 1. (713 aa)
ARHGAP28Rho-GAP domain-containing protein. (695 aa)
CLIP1CAP-Gly domain containing linker protein 1. (1392 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
PRRT2Uncharacterized protein. (359 aa)
FERMT1Fermitin family member 1. (677 aa)
SLF1ANK_REP_REGION domain-containing protein. (414 aa)
KIF9Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (807 aa)
PIK3R2Uncharacterized protein. (738 aa)
LMOD2Leiomodin 2. (553 aa)
AVILAdvillin. (818 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2419 aa)
G3W8M0_SARHAUncharacterized protein. (323 aa)
G3W8Q5_SARHAUncharacterized protein. (148 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2368 aa)
BCL2L11BCL2 like 11. (200 aa)
CARMIL1Uncharacterized protein. (98 aa)
TRABD2ATraB domain containing 2A. (297 aa)
OPRD1Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (308 aa)
MAP1BUncharacterized protein. (2223 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (398 aa)
TAL1BHLH domain-containing protein. (188 aa)
STUB1STIP1 homology and U-box containing protein 1. (256 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (135 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (558 aa)
LMOD1Leiomodin 1. (580 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3068 aa)
STX1BSyntaxin 1B; Belongs to the syntaxin family. (288 aa)
FCHSD1FCH and double SH3 domains 1. (690 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (503 aa)
CTNNBIP1Catenin beta interacting protein 1. (63 aa)
FAF1Fas associated factor 1. (550 aa)
RPS3KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (242 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1675 aa)
PMEPA1Prostate transmembrane protein, androgen induced 1. (282 aa)
TRABD2BUncharacterized protein. (189 aa)
SENP6SUMO specific peptidase 6. (1140 aa)
BMFBcl2 modifying factor. (184 aa)
ADD1Adducin 1. (738 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1264 aa)
DNAJC15DnaJ heat shock protein family (Hsp40) member C15. (148 aa)
MAPRE3Microtubule associated protein RP/EB family member 3. (285 aa)
SVILSupervillin. (2205 aa)
SLC39A12Solute carrier family 39 member 12. (694 aa)
RIOK3Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. (520 aa)
SPTBSpectrin beta chain; Belongs to the spectrin family. (2319 aa)
NCKAP1LNCK associated protein 1 like. (1136 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (754 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
FNIP2Folliculin interacting protein 2. (839 aa)
PREBProlactin regulatory element binding. (420 aa)
SEPTIN8Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (442 aa)
USP50Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (395 aa)
SSH1Slingshot protein phosphatase 1. (950 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5. (1585 aa)
MPP7Membrane palmitoylated protein 7; Belongs to the MAGUK family. (576 aa)
JAM3Junctional adhesion molecule 3. (308 aa)
HIP1RHuntingtin interacting protein 1 related. (1071 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
MTORSerine/threonine-protein kinase mTOR. (1680 aa)
DRG1Developmentally regulated GTP binding protein 1. (259 aa)
TTBK1Tau tubulin kinase 1. (1337 aa)
HAX1HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (277 aa)
FARP2FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1062 aa)
FAM49BFamily with sequence similarity 49 member B. (324 aa)
AJUBAUncharacterized protein. (193 aa)
ANKRA2Ankyrin repeat family A member 2. (313 aa)
LCP1Lymphocyte cytosolic protein 1. (632 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1063 aa)
CRYABCrystallin alpha B; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (174 aa)
THRAThyroid hormone receptor alpha. (408 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (135 aa)
TRAPPC12Trafficking protein particle complex 12. (809 aa)
TMOD4Tropomodulin 4. (453 aa)
WARS1Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (476 aa)
CSF3Colony stimulating factor 3. (221 aa)
TFIP11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (834 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (822 aa)
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 1. (1113 aa)
GBA2Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (892 aa)
TWF1Twinfilin actin binding protein 1. (350 aa)
DBN1Drebrin 1. (693 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1643 aa)
G3WND9_SARHASCY domain-containing protein. (64 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (382 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (511 aa)
SPIDRDUF4503 domain-containing protein. (362 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
G3WQ48_SARHAUncharacterized protein. (246 aa)
SAR1BSecretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (167 aa)
DKK1Uncharacterized protein. (138 aa)
LDLRAD4Low density lipoprotein receptor class A domain containing 4. (269 aa)
NLRC3NLR family CARD domain containing 3. (1071 aa)
ESAMEndothelial cell adhesion molecule. (391 aa)
SORL1Sortilin related receptor 1. (2120 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (588 aa)
G3WRI4_SARHATelomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (396 aa)
EVLEnah/Vasp-like. (305 aa)
TMOD1Tropomodulin 1. (359 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (371 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (359 aa)
CDC42EP4CDC42 effector protein 4. (354 aa)
MTPNMyotrophin. (118 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1290 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2566 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1379 aa)
ADD3Adducin 3. (706 aa)
PARK7Parkinsonism associated deglycase. (192 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
G3WU11_SARHAUncharacterized protein. (123 aa)
VIL1Villin 1. (827 aa)
BAIAP2L1BAI1 associated protein 2 like 1. (512 aa)
STX1ASyntaxin 1A. (204 aa)
TBX20T-box transcription factor 20. (451 aa)
BBS4Bardet-Biedl syndrome 4. (537 aa)
CKAP5Cytoskeleton associated protein 5. (2033 aa)
CDC42EP1CRIB domain-containing protein. (373 aa)
G3WV84_SARHAUncharacterized protein. (534 aa)
CAPZA2F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
ARHGAP40Rho GTPase activating protein 40. (636 aa)
CDH17Cadherin 17. (838 aa)
LMOD3Leiomodin 3. (575 aa)
TMOD2Tropomodulin 2. (353 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (290 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (802 aa)
TMOD3Tropomodulin 3. (352 aa)
ARHGAP18Rho GTPase activating protein 18. (666 aa)
PDE4DIPPhosphodiesterase 4D interacting protein. (2334 aa)
RASA1RAS p21 protein activator 1. (884 aa)
MLST8MTOR associated protein, LST8 homolog. (326 aa)
MAPTMicrotubule-associated protein. (711 aa)
PEX5Peroxisomal biogenesis factor 5. (646 aa)
DCTN1CAP-Gly domain-containing protein. (1283 aa)
TENM1Teneurin transmembrane protein 1. (2038 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (828 aa)
CCL21C-C motif chemokine ligand 21. (139 aa)
BAG4BCL2 associated athanogene 4. (373 aa)
LATS1Large tumor suppressor kinase 1. (1134 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (784 aa)
ATF7IPActivating transcription factor 7 interacting protein. (1099 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (727 aa)
GSNGelsolin. (777 aa)
DMTNHP domain-containing protein. (401 aa)
PSRC1Proline and serine rich coiled-coil 1. (324 aa)
STMN2Stathmin; Belongs to the stathmin family. (179 aa)
TMC8Transmembrane channel-like protein. (719 aa)
SLIT2Slit guidance ligand 2. (1375 aa)
G3X1T9_SARHAUncharacterized protein. (316 aa)
GRB2Growth factor receptor bound protein 2. (191 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (866 aa)
SLAIN2SLAIN motif family member 2. (477 aa)
KANK4KN motif and ankyrin repeat domains 4. (921 aa)
ICE1Uncharacterized protein. (2251 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2472 aa)
SNX9Sorting nexin. (592 aa)
PFN2Profilin; Belongs to the profilin family. (110 aa)
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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