STRINGSTRING
DGAT1 DGAT1 PIK3CB PIK3CB SOCS1 SOCS1 ETNK2 ETNK2 G3VBD4_SARHA G3VBD4_SARHA PIK3C2A PIK3C2A DGKH DGKH LPIN1 LPIN1 MOGAT2 MOGAT2 G3VE45_SARHA G3VE45_SARHA DGKE DGKE UVRAG UVRAG G3VEU8_SARHA G3VEU8_SARHA TAZ TAZ AGPAT2 AGPAT2 G3VG98_SARHA G3VG98_SARHA DGKB DGKB PLA2G15 PLA2G15 RGSL1 RGSL1 MOGAT3 MOGAT3 EFR3B EFR3B G3VIA2_SARHA G3VIA2_SARHA PLD2 PLD2 G3VJE5_SARHA G3VJE5_SARHA HDHD5 HDHD5 G3VKQ2_SARHA G3VKQ2_SARHA G3VKV5_SARHA G3VKV5_SARHA IMPA2 IMPA2 SOCS2 SOCS2 SOCS4 SOCS4 PI4KA PI4KA CHKB CHKB BPNT1 BPNT1 PYURF PYURF TTC7A TTC7A G3VPN9_SARHA G3VPN9_SARHA PIGK PIGK G3VQR7_SARHA G3VQR7_SARHA PIP5K1B PIP5K1B PIGA PIGA GPAA1 GPAA1 PLSCR3 PLSCR3 SH3YL1 SH3YL1 DGAT2 DGAT2 VAC14 VAC14 AGPAT4 AGPAT4 PI4K2B PI4K2B FIG4 FIG4 PTDSS1 PTDSS1 PIK3C2B PIK3C2B ANG ANG PTDSS2 PTDSS2 INPPL1 INPPL1 DGKI DGKI G3VYH5_SARHA G3VYH5_SARHA DPM3 DPM3 INPP4A INPP4A PLD1 PLD1 LPIN2 LPIN2 GPAT3 GPAT3 ITPKB ITPKB IP6K3 IP6K3 LCAT LCAT CHKA CHKA G3W118_SARHA G3W118_SARHA LOC111719032 LOC111719032 PIP4K2C PIP4K2C PIK3R1 PIK3R1 DGKA DGKA CHPT1 CHPT1 PCYT1A PCYT1A IMPAD1 IMPAD1 PIK3R4 PIK3R4 PIK3CG PIK3CG GPAT2 GPAT2 AGPAT3 AGPAT3 ATG14 ATG14 G3W510_SARHA G3W510_SARHA SOCS5 SOCS5 MBOAT7 MBOAT7 SLA2 SLA2 PIKFYVE PIKFYVE PIK3R2 PIK3R2 MPPE1 MPPE1 IPMK IPMK CDIPT CDIPT PGAP2 PGAP2 PCYT2 PCYT2 FAM126A FAM126A PIP4K2A PIP4K2A AGPAT1 AGPAT1 PIGF PIGF FGF2 FGF2 ABHD4 ABHD4 PIGB PIGB ATM ATM G3WBT6_SARHA G3WBT6_SARHA CDS2 CDS2 IMPA1 IMPA1 PLCG2 PLCG2 CEPT1 CEPT1 CLN3 CLN3 PIGH PIGH ETNK1 ETNK1 SLC27A1 SLC27A1 G3WEN1_SARHA G3WEN1_SARHA PGAP4 PGAP4 LPCAT2 LPCAT2 PCK1 PCK1 IP6K2 IP6K2 FAM126B FAM126B PIGG PIGG AJUBA AJUBA PIGQ PIGQ PISD PISD PIGV PIGV PIGS PIGS PIP5K1A PIP5K1A PRR14L PRR14L PIGT PIGT SOCS6 SOCS6 PI4KB PI4KB PIGP PIGP PIGN PIGN PIK3C3 PIK3C3 PCYT1B PCYT1B TTC7B TTC7B DGKQ DGKQ INPP1 INPP1 INPP4B INPP4B PLCE1 PLCE1 PGAP3 PGAP3 CDS1 CDS1 MORN2 MORN2 MOGAT1 MOGAT1 DGKZ DGKZ TMEM150A TMEM150A GPAT4 GPAT4 PIK3CA PIK3CA LPCAT3 LPCAT3 LPCAT1 LPCAT1 PIGO PIGO PLA2G4A PLA2G4A PGAP1 PGAP1 PCK2 PCK2 FAM102B FAM102B ITPKA ITPKA LPIN3 LPIN3 SMG1 SMG1 PTPMT1 PTPMT1 PIGU PIGU PGS1 PGS1 IP6K1 IP6K1 FAR1 FAR1 SOCS3 SOCS3 SOCS7 SOCS7 PEMT PEMT PI4K2A PI4K2A PIGC PIGC G3X1G2_SARHA G3X1G2_SARHA ABHD5 ABHD5 G3X1U4_SARHA G3X1U4_SARHA G3X2F5_SARHA G3X2F5_SARHA FAM102A FAM102A GPAM GPAM DPM1 DPM1 TAMM41 TAMM41 CISH CISH
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DGAT1Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family. (384 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (802 aa)
SOCS1Suppressor of cytokine signaling 1. (154 aa)
ETNK2Ethanolamine kinase 2. (375 aa)
G3VBD4_SARHAUncharacterized protein. (270 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1350 aa)
DGKHDiacylglycerol kinase. (1095 aa)
LPIN1Lipin 1. (927 aa)
MOGAT2Uncharacterized protein. (334 aa)
G3VE45_SARHAUncharacterized protein. (538 aa)
DGKEDiacylglycerol kinase. (570 aa)
UVRAGUncharacterized protein. (179 aa)
G3VEU8_SARHAPNPLA domain-containing protein. (329 aa)
TAZTafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (289 aa)
AGPAT21-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (221 aa)
G3VG98_SARHAUncharacterized protein. (512 aa)
DGKBDAGKa domain-containing protein. (95 aa)
PLA2G15Phospholipase A2 group XV. (388 aa)
RGSL1RGS domain-containing protein. (399 aa)
MOGAT3Monoacylglycerol O-acyltransferase 3. (336 aa)
EFR3BEFR3 homolog B. (814 aa)
G3VIA2_SARHAUncharacterized protein. (603 aa)
PLD2Phospholipase. (934 aa)
G3VJE5_SARHAUncharacterized protein. (327 aa)
HDHD5Haloacid dehalogenase like hydrolase domain containing 5. (393 aa)
G3VKQ2_SARHAKinase; Belongs to the inositol phosphokinase (IPK) family. (345 aa)
G3VKV5_SARHAUncharacterized protein. (438 aa)
IMPA2Inositol-1-monophosphatase. (256 aa)
SOCS2Suppressor of cytokine signaling 2. (199 aa)
SOCS4Suppressor of cytokine signaling 4. (439 aa)
PI4KAPI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (230 aa)
CHKBCholine kinase beta. (360 aa)
BPNT13'(2'), 5'-bisphosphate nucleotidase 1. (308 aa)
PYURFPIGY upstream reading frame. (119 aa)
TTC7ATetratricopeptide repeat domain 7A. (801 aa)
G3VPN9_SARHAPIPK domain-containing protein. (650 aa)
PIGKGPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (350 aa)
G3VQR7_SARHAPLA2c domain-containing protein. (590 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (431 aa)
PIGAPhosphatidylinositol glycan anchor biosynthesis class A. (492 aa)
GPAA1Glycosylphosphatidylinositol anchor attachment 1. (621 aa)
PLSCR3Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (284 aa)
SH3YL1SH3 and SYLF domain containing 1. (341 aa)
DGAT2Diacylglycerol O-acyltransferase 2. (361 aa)
VAC14Uncharacterized protein. (778 aa)
AGPAT41-acylglycerol-3-phosphate O-acyltransferase 4. (380 aa)
PI4K2BPhosphatidylinositol 4-kinase type 2 beta. (390 aa)
FIG4FIG4 phosphoinositide 5-phosphatase. (906 aa)
PTDSS1Phosphatidylserine synthase 1. (433 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1643 aa)
ANGAngiogenin; Belongs to the pancreatic ribonuclease family. (153 aa)
PTDSS2Phosphatidylserine synthase 2. (366 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (958 aa)
DGKIANK_REP_REGION domain-containing protein. (126 aa)
G3VYH5_SARHAUncharacterized protein. (478 aa)
DPM3Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family. (92 aa)
INPP4AInositol polyphosphate-4-phosphatase type I A. (968 aa)
PLD1Phospholipase. (946 aa)
LPIN2Lipin 2. (898 aa)
GPAT3Glycerol-3-phosphate acyltransferase 3. (438 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (298 aa)
IP6K3Kinase; Belongs to the inositol phosphokinase (IPK) family. (403 aa)
LCATLecithin-cholesterol acyltransferase. (446 aa)
CHKACholine kinase alpha. (341 aa)
G3W118_SARHATYR_PHOSPHATASE_2 domain-containing protein. (203 aa)
LOC111719032Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (390 aa)
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (363 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
DGKADiacylglycerol kinase. (788 aa)
CHPT1Choline phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (339 aa)
PCYT1APhosphate cytidylyltransferase 1, choline, alpha. (323 aa)
IMPAD1Inositol monophosphatase domain containing 1. (231 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1363 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1103 aa)
GPAT2Glycerol-3-phosphate acyltransferase 2, mitochondrial. (792 aa)
AGPAT3PlsC domain-containing protein. (378 aa)
ATG14Autophagy related 14. (511 aa)
G3W510_SARHAKinase; Belongs to the inositol phosphokinase (IPK) family. (650 aa)
SOCS5Suppressor of cytokine signaling 5. (539 aa)
MBOAT7Membrane bound O-acyltransferase domain containing 7; Belongs to the membrane-bound acyltransferase family. (406 aa)
SLA2Src like adaptor 2. (294 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2164 aa)
PIK3R2Uncharacterized protein. (738 aa)
MPPE1Metallophosphoesterase 1. (375 aa)
IPMKKinase; Belongs to the inositol phosphokinase (IPK) family. (356 aa)
CDIPTCDP-diacylglycerol--inositol 3-phosphatidyltransferase. (148 aa)
PGAP2Post-GPI attachment to proteins 2. (255 aa)
PCYT2Phosphate cytidylyltransferase 2, ethanolamine. (370 aa)
FAM126AFamily with sequence similarity 126 member A. (517 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (365 aa)
AGPAT11-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (287 aa)
PIGFPhosphatidylinositol glycan anchor biosynthesis class F. (219 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (203 aa)
ABHD4Abhydrolase domain containing 4. (355 aa)
PIGBMannosyltransferase. (363 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3068 aa)
G3WBT6_SARHAUncharacterized protein. (261 aa)
CDS2Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (447 aa)
IMPA1Inositol-1-monophosphatase. (279 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1264 aa)
CEPT1Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (416 aa)
CLN3Battenin. (438 aa)
PIGHPhosphatidylinositol glycan anchor biosynthesis class H. (190 aa)
ETNK1Uncharacterized protein. (170 aa)
SLC27A1Solute carrier family 27 member 1. (646 aa)
G3WEN1_SARHAUncharacterized protein. (529 aa)
PGAP4Transmembrane protein 246. (404 aa)
LPCAT2Lysophosphatidylcholine acyltransferase 2. (554 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (624 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (447 aa)
FAM126BFamily with sequence similarity 126 member B. (530 aa)
PIGGPhosphatidylinositol glycan anchor biosynthesis class G. (984 aa)
AJUBAUncharacterized protein. (193 aa)
PIGQUncharacterized protein. (314 aa)
PISDPhosphatidylserine decarboxylase. (373 aa)
PIGVGPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. (495 aa)
PIGSPhosphatidylinositol glycan anchor biosynthesis class S. (579 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (547 aa)
PRR14LTantalus domain-containing protein. (2068 aa)
PIGTPhosphatidylinositol glycan anchor biosynthesis class T. (582 aa)
SOCS6Suppressor of cytokine signaling 6. (517 aa)
PI4KBPhosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family. (811 aa)
PIGPPhosphatidylinositol N-acetylglucosaminyltransferase subunit P; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. (134 aa)
PIGNPhosphatidylinositol glycan anchor biosynthesis class N. (791 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (742 aa)
PCYT1BPhosphate cytidylyltransferase 1, choline, beta. (369 aa)
TTC7BTetratricopeptide repeat domain 7B. (801 aa)
DGKQDiacylglycerol kinase. (859 aa)
INPP1Inositol polyphosphate-1-phosphatase. (402 aa)
INPP4BInositol polyphosphate-4-phosphatase type II B. (779 aa)
PLCE1Phosphoinositide phospholipase C. (1808 aa)
PGAP3Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. (258 aa)
CDS1Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (381 aa)
MORN2Uncharacterized protein. (169 aa)
MOGAT1Monoacylglycerol O-acyltransferase 1. (335 aa)
DGKZDiacylglycerol kinase zeta. (781 aa)
TMEM150ATransmembrane protein 150A. (271 aa)
GPAT4Glycerol-3-phosphate acyltransferase 4. (455 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
LPCAT3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (440 aa)
LPCAT1Lysophosphatidylcholine acyltransferase 1. (486 aa)
PIGOPhosphatidylinositol glycan anchor biosynthesis class O. (1093 aa)
PLA2G4APhospholipase A2. (755 aa)
PGAP1Post-GPI attachment to proteins 1. (930 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
FAM102BFamily with sequence similarity 102 member B. (362 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (120 aa)
LPIN3LNS2 domain-containing protein. (903 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3638 aa)
PTPMT1TYR_PHOSPHATASE_2 domain-containing protein. (155 aa)
PIGUPhosphatidylinositol glycan anchor biosynthesis class U. (435 aa)
PGS1CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family. (509 aa)
IP6K1Kinase; Belongs to the inositol phosphokinase (IPK) family. (441 aa)
FAR1Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (492 aa)
SOCS3Suppressor of cytokine signaling 3. (228 aa)
SOCS7Suppressor of cytokine signaling 7. (568 aa)
PEMTPhosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family. (199 aa)
PI4K2API3K/PI4K domain-containing protein. (344 aa)
PIGCPhosphatidylinositol glycan anchor biosynthesis class C. (297 aa)
G3X1G2_SARHAUncharacterized protein. (325 aa)
ABHD5Abhydrolase domain containing 5. (337 aa)
G3X1U4_SARHAPlsC domain-containing protein. (376 aa)
G3X2F5_SARHAPIPK domain-containing protein. (487 aa)
FAM102AFamily with sequence similarity 102 member A. (336 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (830 aa)
DPM1Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (266 aa)
TAMM41Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane. (294 aa)
CISHCytokine inducible SH2 containing protein. (253 aa)
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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