STRINGSTRING
GREB1 GREB1 SRD5A2 SRD5A2 KLHL10 KLHL10 ROR2 ROR2 G3VL00_SARHA G3VL00_SARHA DHCR24 DHCR24 HNF1B HNF1B BAK1 BAK1 AXL AXL G3VSY5_SARHA G3VSY5_SARHA PTPN11 PTPN11 HSD17B3 HSD17B3 TP63 TP63 CTNNB1 CTNNB1 ASB1 ASB1 CHD7 CHD7 STRA6 STRA6 GREB1L GREB1L LGR4 LGR4 BMP6 BMP6 PDGFRA PDGFRA WNT9B WNT9B ESR1 ESR1 G3WRP0_SARHA G3WRP0_SARHA MERTK MERTK HOXD13 HOXD13 PKD1 PKD1 HOXA13 HOXA13 AR AR LRP2 LRP2 TYRO3 TYRO3 WT1 WT1 G3WYL0_SARHA G3WYL0_SARHA G3X0T6_SARHA G3X0T6_SARHA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GREB1Uncharacterized protein. (1951 aa)
SRD5A23-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (252 aa)
KLHL10Kelch like family member 10. (650 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1022 aa)
G3VL00_SARHAUncharacterized protein. (503 aa)
DHCR2424-dehydrocholesterol reductase. (365 aa)
HNF1BHNF1 homeobox B. (558 aa)
BAK1BCL2 antagonist/killer 1. (208 aa)
AXLAXL receptor tyrosine kinase. (864 aa)
G3VSY5_SARHAUncharacterized protein. (1521 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (602 aa)
HSD17B3Hydroxysteroid 17-beta dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (310 aa)
TP63Tumor protein p63. (458 aa)
CTNNB1Catenin beta 1. (781 aa)
ASB1Ankyrin repeat and SOCS box containing 1. (335 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2999 aa)
STRA6Uncharacterized protein. (487 aa)
GREB1LUncharacterized protein. (724 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (889 aa)
BMP6Bone morphogenetic protein 6. (439 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1101 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (588 aa)
G3WRP0_SARHAUncharacterized protein. (372 aa)
MERTKUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (571 aa)
HOXD13Homeobox D13. (285 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4232 aa)
HOXA13Homeobox domain-containing protein. (190 aa)
ARUncharacterized protein. (388 aa)
LRP2Uncharacterized protein. (3969 aa)
TYRO3TYRO3 protein tyrosine kinase. (841 aa)
WT1WT1 transcription factor. (399 aa)
G3WYL0_SARHAUncharacterized protein. (681 aa)
G3X0T6_SARHAUncharacterized protein. (1188 aa)
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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