STRINGSTRING
GATA3 GATA3 JAG2 JAG2 GBX2 GBX2 TSKU TSKU WNT1 WNT1 KCNQ1 KCNQ1 G3VFR5_SARHA G3VFR5_SARHA G3VGL8_SARHA G3VGL8_SARHA BMP4 BMP4 WHRN WHRN FREM2 FREM2 LRRC51 LRRC51 G3VL00_SARHA G3VL00_SARHA ATG4B ATG4B ADAM10 ADAM10 ANP32B ANP32B TFAP2A TFAP2A TBX3 TBX3 FZD6 FZD6 SLC26A5 SLC26A5 TSHR TSHR COL2A1 COL2A1 NOTCH1 NOTCH1 G3VR94_SARHA G3VR94_SARHA G3VRC6_SARHA G3VRC6_SARHA GABRA5 GABRA5 CXCL14 CXCL14 ZEB1 ZEB1 LRIG3 LRIG3 GSDME GSDME G3VTN7_SARHA G3VTN7_SARHA SCRIB SCRIB DLX5 DLX5 MYO15A MYO15A CTHRC1 CTHRC1 PTPN11 PTPN11 DVL3 DVL3 STOX1 STOX1 SEC24B SEC24B FRZB FRZB TTC39C TTC39C G3VWZ7_SARHA G3VWZ7_SARHA RIPOR2 RIPOR2 C1QTNF5 C1QTNF5 CCM2 CCM2 G3VZM2_SARHA G3VZM2_SARHA OTOP1 OTOP1 CECR2 CECR2 GJB2 GJB2 SLC44A4 SLC44A4 GRXCR2 GRXCR2 TMIE TMIE CDH23 CDH23 RPGRIP1L RPGRIP1L DVL2 DVL2 GRHL3 GRHL3 S1PR2 S1PR2 TPRN TPRN ATOH1 ATOH1 G3W5D9_SARHA G3W5D9_SARHA G3W5H9_SARHA G3W5H9_SARHA TRIP11 TRIP11 WDPCP WDPCP ALDH1A3 ALDH1A3 KCNQ4 KCNQ4 GLI3 GLI3 EYA1 EYA1 PJVK PJVK GRXCR1 GRXCR1 FGF2 FGF2 ATG5 ATG5 FOXG1 FOXG1 OTX1 OTX1 LRIG1 LRIG1 MCM2 MCM2 LHX3 LHX3 CHD7 CHD7 SLC17A8 SLC17A8 PAX8 PAX8 BMPER BMPER TBX2 TBX2 BLOC1S5 BLOC1S5 MKS1 MKS1 MYO6 MYO6 BMP2 BMP2 PTK7 PTK7 HESX1 HESX1 IFT20 IFT20 CYTL1 CYTL1 LHFPL5 LHFPL5 ITGA8 ITGA8 EYA4 EYA4 PTPRQ PTPRQ INSIG1 INSIG1 PAFAH1B1 PAFAH1B1 SDC4 SDC4 PDZD7 PDZD7 G3WKZ4_SARHA G3WKZ4_SARHA G3WLT4_SARHA G3WLT4_SARHA STRC STRC TTC8 TTC8 C1QC C1QC HES5 HES5 DLL1 DLL1 NAGLU NAGLU PHOX2B PHOX2B TCAP TCAP PLS1 PLS1 G3WSB4_SARHA G3WSB4_SARHA MCOLN3 MCOLN3 SIX4 SIX4 GATA2 GATA2 REST REST G3WUU6_SARHA G3WUU6_SARHA ROR1 ROR1 CLRN2 CLRN2 PROX1 PROX1 HOXA13 HOXA13 HOXA1 HOXA1 SLC4A7 SLC4A7 SOBP SOBP PCDH15 PCDH15 FZD3 FZD3 USH1C USH1C LRRC1 LRRC1 CHRNA9 CHRNA9 MAPKAPK2 MAPKAPK2 CLRN1 CLRN1 KCNK2 KCNK2 JAG1 JAG1 FOXI1 FOXI1 INSIG2 INSIG2 USH1G USH1G G3X3F5_SARHA G3X3F5_SARHA SLC9A3R1 SLC9A3R1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GATA3GATA binding protein 3. (444 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1245 aa)
GBX2Homeobox domain-containing protein. (199 aa)
TSKUTsukushi, small leucine rich proteoglycan. (353 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (342 aa)
KCNQ1Ion_trans domain-containing protein; Belongs to the potassium channel family. (329 aa)
G3VFR5_SARHAUncharacterized protein. (335 aa)
G3VGL8_SARHAUncharacterized protein. (300 aa)
BMP4Bone morphogenetic protein 4. (410 aa)
WHRNWhirlin. (798 aa)
FREM2FRAS1 related extracellular matrix 2. (3178 aa)
LRRC51Uncharacterized protein. (325 aa)
G3VL00_SARHAUncharacterized protein. (503 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (401 aa)
ADAM10ADAM metallopeptidase domain 10. (754 aa)
ANP32BAcidic nuclear phosphoprotein 32 family member B. (263 aa)
TFAP2ATranscription factor AP-2 alpha. (443 aa)
TBX3T-box transcription factor 3. (682 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (718 aa)
SLC26A5Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (747 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (705 aa)
COL2A1Collagen type II alpha 1 chain. (1491 aa)
NOTCH1Notch receptor 1. (2672 aa)
G3VR94_SARHAUncharacterized protein; Belongs to the peptidase S1 family. (452 aa)
G3VRC6_SARHAUncharacterized protein. (397 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (463 aa)
CXCL14C-X-C motif chemokine ligand 14. (100 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1101 aa)
LRIG3Leucine rich repeats and immunoglobulin like domains 3. (994 aa)
GSDMEGasdermin E. (500 aa)
G3VTN7_SARHAUncharacterized protein. (502 aa)
SCRIBScribble planar cell polarity protein. (1625 aa)
DLX5Distal-less homeobox 5. (163 aa)
MYO15AMyosin XVA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3566 aa)
CTHRC1Collagen triple helix repeat containing 1. (247 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (602 aa)
DVL3Uncharacterized protein. (272 aa)
STOX1Stork_head domain-containing protein. (897 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1213 aa)
FRZBFrizzled related protein. (321 aa)
TTC39CTetratricopeptide repeat domain 39C. (526 aa)
G3VWZ7_SARHAMyosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (758 aa)
RIPOR2PL48 domain-containing protein. (1081 aa)
C1QTNF5C1q and TNF related 5. (199 aa)
CCM2CCM2 scaffold protein. (452 aa)
G3VZM2_SARHAUncharacterized protein. (2931 aa)
OTOP1Otopetrin 1. (471 aa)
CECR2CECR2 histone acetyl-lysine reader. (985 aa)
GJB2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (226 aa)
SLC44A4Solute carrier family 44 member 4; Belongs to the CTL (choline transporter-like) family. (708 aa)
GRXCR2Glutaredoxin and cysteine rich domain containing 2. (247 aa)
TMIETransmembrane inner ear. (147 aa)
CDH23Cadherin related 23. (2976 aa)
RPGRIP1LRPGRIP1 like. (1268 aa)
DVL2Dishevelled segment polarity protein 2. (731 aa)
GRHL3Grainyhead like transcription factor 3. (599 aa)
S1PR2Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (350 aa)
TPRNPhostensin domain-containing protein. (656 aa)
ATOH1Atonal bHLH transcription factor 1. (364 aa)
G3W5D9_SARHALaminin N-terminal domain-containing protein. (181 aa)
G3W5H9_SARHAMCM domain-containing protein; Belongs to the MCM family. (393 aa)
TRIP11Thyroid hormone receptor interactor 11. (1975 aa)
WDPCPWD repeat containing planar cell polarity effector. (720 aa)
ALDH1A3Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (512 aa)
KCNQ4Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (599 aa)
GLI3GLI family zinc finger 3. (1583 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (552 aa)
PJVKPejvakin. (354 aa)
GRXCR1Glutaredoxin and cysteine rich domain containing 1. (291 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (203 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
FOXG1Forkhead box G1. (455 aa)
OTX1Orthodenticle homeobox 1. (360 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (984 aa)
MCM2Uncharacterized protein. (483 aa)
LHX3LIM homeobox 3. (403 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2999 aa)
SLC17A8Solute carrier family 17 member 8. (589 aa)
PAX8Paired box 8. (457 aa)
BMPERBMP binding endothelial regulator. (586 aa)
TBX2T-box transcription factor 2. (653 aa)
BLOC1S5Biogenesis of lysosome-related organelles complex 1 subunit 5; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). (195 aa)
MKS1MKS transition zone complex subunit 1. (563 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1294 aa)
BMP2Bone morphogenetic protein 2. (394 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1062 aa)
HESX1HESX homeobox 1. (189 aa)
IFT20Intraflagellar transport 20. (133 aa)
CYTL1Cytokine like 1. (140 aa)
LHFPL5LHFPL tetraspan subfamily member 5. (227 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (997 aa)
EYA4Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (619 aa)
PTPRQUncharacterized protein. (134 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (203 aa)
PDZD7Uncharacterized protein. (451 aa)
G3WKZ4_SARHAPDZ domain-containing protein. (80 aa)
G3WLT4_SARHAUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (886 aa)
STRCStereocilin. (1769 aa)
TTC8Tetratricopeptide repeat domain 8. (506 aa)
C1QCC1q domain-containing protein. (369 aa)
HES5Hes family bHLH transcription factor 5. (165 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (733 aa)
NAGLUN-acetyl-alpha-glucosaminidase. (618 aa)
PHOX2BPaired like homeobox 2B. (267 aa)
TCAPTitin-cap. (171 aa)
PLS1Plastin 1. (636 aa)
G3WSB4_SARHAWD_REPEATS_REGION domain-containing protein. (393 aa)
MCOLN3Mucolipin 3. (489 aa)
SIX4SIX homeobox 4. (685 aa)
GATA2GATA binding protein 2. (398 aa)
RESTUncharacterized protein. (918 aa)
G3WUU6_SARHAUncharacterized protein. (396 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (882 aa)
CLRN2Clarin 2. (233 aa)
PROX1Prospero homeobox 1. (664 aa)
HOXA13Homeobox domain-containing protein. (190 aa)
HOXA1Homeobox A1. (333 aa)
SLC4A7Anion exchange protein. (1217 aa)
SOBPUncharacterized protein. (661 aa)
PCDH15Uncharacterized protein. (598 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
USH1CUSH1 protein network component harmonin. (884 aa)
LRRC1Leucine rich repeat containing 1. (574 aa)
CHRNA9Cholinergic receptor nicotinic alpha 9 subunit. (477 aa)
MAPKAPK2MAPK activated protein kinase 2. (307 aa)
CLRN1Clarin 1. (149 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (322 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1189 aa)
FOXI1Forkhead box I1. (377 aa)
INSIG2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (239 aa)
USH1GUSH1 protein network component sans. (462 aa)
G3X3F5_SARHAUncharacterized protein. (207 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (343 aa)
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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