(27 nodes) Lung morphogenesis network (Sarcophilus harrisii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G3VA64_SARHA	RRM domain-containing protein. (423 aa)
	FOXA1	Forkhead box A1. (494 aa)
	PLOD3	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (757 aa)
	TCF21	Transcription factor 21. (179 aa)
	DLG5	Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1956 aa)
	CELSR1	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2555 aa)
	SEC24B	SEC24 homolog B, COPII coat complex component. (1213 aa)
	SPRY1	Sprouty RTK signaling antagonist 1. (319 aa)
	CTSH	Cathepsin H; Belongs to the peptidase C1 family. (334 aa)
	MAPK1	Mitogen-activated protein kinase. (348 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	LIF	LIF interleukin 6 family cytokine. (202 aa)
	NODAL	Nodal growth differentiation factor. (326 aa)
	MAPK3	Mitogen-activated protein kinase. (375 aa)
	RSPO2	R-spondin 2. (243 aa)
	HHIP	Hedgehog interacting protein. (701 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (409 aa)
	SRF	Serum response factor. (306 aa)
	CTSZ	Cathepsin Z; Belongs to the peptidase C1 family. (308 aa)
	RDH10	Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
	HPS1	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (711 aa)
	HOXA5	Homeobox A5. (271 aa)
	DAG1	Dystroglycan 1. (895 aa)
	WNT2B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (290 aa)
	WNT2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
	AP3B1	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1086 aa)
	STK40	Serine/threonine kinase 40. (435 aa)

Your Current Organism:

Sarcophilus harrisii

NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTNNB1	MAPK1	ENSSHAP00000009775	ENSSHAP00000008915	Catenin beta 1.	Mitogen-activated protein kinase.	0.490
CTNNB1	MAPK3	ENSSHAP00000009775	ENSSHAP00000012745	Catenin beta 1.	Mitogen-activated protein kinase.	0.490
CTNNB1	TGFBR2	ENSSHAP00000009775	ENSSHAP00000014662	Catenin beta 1.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.498
CTNNB1	WNT2	ENSSHAP00000009775	ENSSHAP00000020263	Catenin beta 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.566
CTNNB1	WNT2B	ENSSHAP00000009775	ENSSHAP00000020232	Catenin beta 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.566
CTSH	CTSZ	ENSSHAP00000008593	ENSSHAP00000015579	Cathepsin H; Belongs to the peptidase C1 family.	Cathepsin Z; Belongs to the peptidase C1 family.	0.528
CTSZ	CTSH	ENSSHAP00000015579	ENSSHAP00000008593	Cathepsin Z; Belongs to the peptidase C1 family.	Cathepsin H; Belongs to the peptidase C1 family.	0.528
MAPK1	CTNNB1	ENSSHAP00000008915	ENSSHAP00000009775	Mitogen-activated protein kinase.	Catenin beta 1.	0.490
MAPK1	MAPK3	ENSSHAP00000008915	ENSSHAP00000012745	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.901
MAPK3	CTNNB1	ENSSHAP00000012745	ENSSHAP00000009775	Mitogen-activated protein kinase.	Catenin beta 1.	0.490
MAPK3	MAPK1	ENSSHAP00000012745	ENSSHAP00000008915	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.901
SRF	TCF21	ENSSHAP00000014927	ENSSHAP00000005574	Serum response factor.	Transcription factor 21.	0.489
TCF21	SRF	ENSSHAP00000005574	ENSSHAP00000014927	Transcription factor 21.	Serum response factor.	0.489
TGFBR2	CTNNB1	ENSSHAP00000014662	ENSSHAP00000009775	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Catenin beta 1.	0.498
WNT2	CTNNB1	ENSSHAP00000020263	ENSSHAP00000009775	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Catenin beta 1.	0.566
WNT2B	CTNNB1	ENSSHAP00000020232	ENSSHAP00000009775	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Catenin beta 1.	0.566