STRINGSTRING
STXBP3 STXBP3 TYRO3 TYRO3 P2RY12 P2RY12 ITGB3 ITGB3 PLEK PLEK G3VHK5_SARHA G3VHK5_SARHA GP1BA GP1BA GATA1 GATA1 UBASH3B UBASH3B COMP COMP BLOC1S4 BLOC1S4 SLC7A11 SLC7A11 PDGFRA PDGFRA FGG FGG FGB FGB STXBP1 STXBP1 PTPN6 PTPN6 PEAR1 PEAR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STXBP3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (597 aa)
TYRO3TYRO3 protein tyrosine kinase. (841 aa)
P2RY12Purinergic receptor P2Y12. (343 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
PLEKPleckstrin. (350 aa)
G3VHK5_SARHAUncharacterized protein. (631 aa)
GP1BALRRCT domain-containing protein. (706 aa)
GATA1Uncharacterized protein. (331 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (630 aa)
COMPCartilage oligomeric matrix protein. (761 aa)
BLOC1S4Uncharacterized protein. (156 aa)
SLC7A11Solute carrier family 7 member 11. (504 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1101 aa)
FGGFibrinogen gamma chain. (443 aa)
FGBFibrinogen beta chain. (494 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (580 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
PEAR1Platelet endothelial aggregation receptor 1. (1047 aa)
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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