(44 nodes) Protein complex involved in cell adhesion network (Sarcophilus harrisii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (784 aa)
	ITGB8	Integrin beta; Belongs to the integrin beta chain family. (726 aa)
	G3VDC3_SARHA	Integrin_alpha2 domain-containing protein. (216 aa)
	ITGB7	Integrin beta; Belongs to the integrin beta chain family. (808 aa)
	LOC100922451	VWFA domain-containing protein; Belongs to the integrin alpha chain family. (1160 aa)
	LGALS1	Galectin. (135 aa)
	G3VNX1_SARHA	VWFA domain-containing protein. (1185 aa)
	PLAUR	Uncharacterized protein. (246 aa)
	LAMB1	Laminin subunit beta 1. (1788 aa)
	ITGA11	Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1163 aa)
	ITGAL	Integrin subunit alpha L; Belongs to the integrin alpha chain family. (1258 aa)
	CD80	Uncharacterized protein. (311 aa)
	ITGAM	VWFA domain-containing protein; Belongs to the integrin alpha chain family. (785 aa)
	ITGA10	Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1166 aa)
	ITGB4	Integrin beta. (1796 aa)
	PLAU	Plasminogen activator, urokinase. (431 aa)
	ITGAV	Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1013 aa)
	TNC	Tenascin C. (1730 aa)
	ITGA7	Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1169 aa)
	ITGB5	Integrin beta; Belongs to the integrin beta chain family. (800 aa)
	G3WA86_SARHA	Galectin. (132 aa)
	G3WAS8_SARHA	Galectin. (136 aa)
	G3WAT5_SARHA	Integrin_alpha2 domain-containing protein. (367 aa)
	ITGB6	Integrin beta; Belongs to the integrin beta chain family. (788 aa)
	G3WBR7_SARHA	Galectin. (147 aa)
	G3WBW0_SARHA	VWFA domain-containing protein; Belongs to the integrin alpha chain family. (881 aa)
	ITGA5	Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1061 aa)
	JAM2	Junctional adhesion molecule 2. (297 aa)
	LYN	Tyrosine-protein kinase. (514 aa)
	ITGA9	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (494 aa)
	EMILIN1	EMI domain-containing protein. (133 aa)
	ITGA3	Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1051 aa)
	VTN	SMB domain-containing protein. (474 aa)
	JAM3	Junctional adhesion molecule 3. (308 aa)
	ITGA8	Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (997 aa)
	TNN	Tenascin N. (1243 aa)
	ITGA4	Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
	ITGAD	Integrin subunit alpha D; Belongs to the integrin alpha chain family. (1162 aa)
	TNR	Tenascin R. (1358 aa)
	ITGA2B	Integrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1057 aa)
	CTLA4	Cytotoxic T-lymphocyte associated protein 4. (223 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (799 aa)
	LGALS2	Galectin. (130 aa)
	ITGA6	Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1080 aa)

Your Current Organism:

Sarcophilus harrisii

NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD80	CTLA4	ENSSHAP00000008651	ENSSHAP00000019057	Uncharacterized protein.	Cytotoxic T-lymphocyte associated protein 4.	0.998
CD80	ITGAL	ENSSHAP00000008651	ENSSHAP00000008221	Uncharacterized protein.	Integrin subunit alpha L; Belongs to the integrin alpha chain family.	0.451
CD80	LYN	ENSSHAP00000008651	ENSSHAP00000013646	Uncharacterized protein.	Tyrosine-protein kinase.	0.554
CTLA4	CD80	ENSSHAP00000019057	ENSSHAP00000008651	Cytotoxic T-lymphocyte associated protein 4.	Uncharacterized protein.	0.998
CTLA4	LYN	ENSSHAP00000019057	ENSSHAP00000013646	Cytotoxic T-lymphocyte associated protein 4.	Tyrosine-protein kinase.	0.421
G3VDC3_SARHA	G3WBW0_SARHA	ENSSHAP00000001177	ENSSHAP00000012915	Integrin_alpha2 domain-containing protein.	VWFA domain-containing protein; Belongs to the integrin alpha chain family.	0.578
G3VDC3_SARHA	ITGA10	ENSSHAP00000001177	ENSSHAP00000021980	Integrin_alpha2 domain-containing protein.	Integrin subunit alpha 10; Belongs to the integrin alpha chain family.	0.479
G3VDC3_SARHA	ITGA2B	ENSSHAP00000001177	ENSSHAP00000018932	Integrin_alpha2 domain-containing protein.	Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.	0.428
G3VDC3_SARHA	ITGA3	ENSSHAP00000001177	ENSSHAP00000014874	Integrin_alpha2 domain-containing protein.	Integrin subunit alpha 3; Belongs to the integrin alpha chain family.	0.539
G3VDC3_SARHA	ITGA6	ENSSHAP00000001177	ENSSHAP00000020410	Integrin_alpha2 domain-containing protein.	Integrin subunit alpha 6; Belongs to the integrin alpha chain family.	0.611
G3VDC3_SARHA	ITGA7	ENSSHAP00000001177	ENSSHAP00000011190	Integrin_alpha2 domain-containing protein.	Integrin subunit alpha 7; Belongs to the integrin alpha chain family.	0.514
G3VDC3_SARHA	ITGA8	ENSSHAP00000001177	ENSSHAP00000015216	Integrin_alpha2 domain-containing protein.	Integrin subunit alpha 8; Belongs to the integrin alpha chain family.	0.514
G3VDC3_SARHA	ITGAV	ENSSHAP00000001177	ENSSHAP00000010452	Integrin_alpha2 domain-containing protein.	Integrin subunit alpha V; Belongs to the integrin alpha chain family.	0.575
G3VDC3_SARHA	ITGB1	ENSSHAP00000001177	ENSSHAP00000019282	Integrin_alpha2 domain-containing protein.	Integrin beta; Belongs to the integrin beta chain family.	0.936
G3VDC3_SARHA	ITGB3	ENSSHAP00000001177	ENSSHAP00000020984	Integrin_alpha2 domain-containing protein.	Integrin beta; Belongs to the integrin beta chain family.	0.767
G3VDC3_SARHA	ITGB4	ENSSHAP00000001177	ENSSHAP00000020995	Integrin_alpha2 domain-containing protein.	Integrin beta.	0.682
G3VDC3_SARHA	ITGB5	ENSSHAP00000001177	ENSSHAP00000011860	Integrin_alpha2 domain-containing protein.	Integrin beta; Belongs to the integrin beta chain family.	0.692
G3VDC3_SARHA	ITGB6	ENSSHAP00000001177	ENSSHAP00000012632	Integrin_alpha2 domain-containing protein.	Integrin beta; Belongs to the integrin beta chain family.	0.643
G3VDC3_SARHA	ITGB7	ENSSHAP00000001177	ENSSHAP00000001367	Integrin_alpha2 domain-containing protein.	Integrin beta; Belongs to the integrin beta chain family.	0.605
G3VDC3_SARHA	ITGB8	ENSSHAP00000001177	ENSSHAP00000000970	Integrin_alpha2 domain-containing protein.	Integrin beta; Belongs to the integrin beta chain family.	0.508