(15 nodes) Regulation of early endosome to late endosome transport network (Sarcophilus harrisii)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MSN	FERM domain-containing protein. (234 aa)
	G3VKI5_SARHA	ERM domain-containing protein. (220 aa)
	LOC100926479	PX domain-containing protein. (168 aa)
	LOC100924383	FERM domain-containing protein. (378 aa)
	SNX12	PX domain-containing protein. (112 aa)
	PTPN23	Uncharacterized protein. (1109 aa)
	MAPK1	Mitogen-activated protein kinase. (348 aa)
	DAB2	PID domain-containing protein. (457 aa)
	G3W2I8_SARHA	BRO1 domain-containing protein. (571 aa)
	EZR	Ezrin. (586 aa)
	VPS11	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (935 aa)
	MAPK3	Mitogen-activated protein kinase. (375 aa)
	DENND10	UDENN domain-containing protein. (356 aa)
	DNAJC13	DnaJ heat shock protein family (Hsp40) member C13. (2245 aa)
	SNX3	Sorting nexin 3. (181 aa)

Your Current Organism:

Sarcophilus harrisii

NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EZR	LOC100924383	ENSSHAP00000011003	ENSSHAP00000004206	Ezrin.	FERM domain-containing protein.	0.992
EZR	MSN	ENSSHAP00000011003	ENSSHAP00000000699	Ezrin.	FERM domain-containing protein.	0.993
G3VKI5_SARHA	LOC100924383	ENSSHAP00000003690	ENSSHAP00000004206	ERM domain-containing protein.	FERM domain-containing protein.	0.883
G3VKI5_SARHA	MSN	ENSSHAP00000003690	ENSSHAP00000000699	ERM domain-containing protein.	FERM domain-containing protein.	0.894
G3W2I8_SARHA	MAPK1	ENSSHAP00000009643	ENSSHAP00000008915	BRO1 domain-containing protein.	Mitogen-activated protein kinase.	0.449
G3W2I8_SARHA	MAPK3	ENSSHAP00000009643	ENSSHAP00000012745	BRO1 domain-containing protein.	Mitogen-activated protein kinase.	0.449
G3W2I8_SARHA	PTPN23	ENSSHAP00000009643	ENSSHAP00000008711	BRO1 domain-containing protein.	Uncharacterized protein.	0.936
LOC100924383	EZR	ENSSHAP00000004206	ENSSHAP00000011003	FERM domain-containing protein.	Ezrin.	0.992
LOC100924383	G3VKI5_SARHA	ENSSHAP00000004206	ENSSHAP00000003690	FERM domain-containing protein.	ERM domain-containing protein.	0.883
LOC100924383	MSN	ENSSHAP00000004206	ENSSHAP00000000699	FERM domain-containing protein.	FERM domain-containing protein.	0.990
LOC100926479	SNX12	ENSSHAP00000003876	ENSSHAP00000005321	PX domain-containing protein.	PX domain-containing protein.	0.901
MAPK1	G3W2I8_SARHA	ENSSHAP00000008915	ENSSHAP00000009643	Mitogen-activated protein kinase.	BRO1 domain-containing protein.	0.449
MAPK1	MAPK3	ENSSHAP00000008915	ENSSHAP00000012745	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.901
MAPK1	PTPN23	ENSSHAP00000008915	ENSSHAP00000008711	Mitogen-activated protein kinase.	Uncharacterized protein.	0.449
MAPK3	G3W2I8_SARHA	ENSSHAP00000012745	ENSSHAP00000009643	Mitogen-activated protein kinase.	BRO1 domain-containing protein.	0.449
MAPK3	MAPK1	ENSSHAP00000012745	ENSSHAP00000008915	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.901
MAPK3	PTPN23	ENSSHAP00000012745	ENSSHAP00000008711	Mitogen-activated protein kinase.	Uncharacterized protein.	0.449
MSN	EZR	ENSSHAP00000000699	ENSSHAP00000011003	FERM domain-containing protein.	Ezrin.	0.993
MSN	G3VKI5_SARHA	ENSSHAP00000000699	ENSSHAP00000003690	FERM domain-containing protein.	ERM domain-containing protein.	0.894
MSN	LOC100924383	ENSSHAP00000000699	ENSSHAP00000004206	FERM domain-containing protein.	FERM domain-containing protein.	0.990