(33 nodes) Pyridoxal phosphate-dependent transferase, major domain network (Sarcophilus harrisii)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	GPT	Glutamic--pyruvic transaminase. (495 aa)
	G3W2Y8_SARHA	Aminotran_1_2 domain-containing protein. (544 aa)
	ALAS2	5'-aminolevulinate synthase 2. (677 aa)
	SEPSECS	O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. (507 aa)
	GLDC	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1034 aa)
	SCLY	Selenocysteine lyase. (437 aa)
	OAT	Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa)
	KYAT3	Kynurenine aminotransferase 3. (452 aa)
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
	SPTLC1	Serine palmitoyltransferase long chain base subunit 1. (473 aa)
	CSAD	Cysteine sulfinic acid decarboxylase. (497 aa)
	ACCS	1-aminocyclopropane-1-carboxylate synthase homolog (inactive). (571 aa)
	AADAT	Aminoadipate aminotransferase. (425 aa)
	GCAT	Glycine C-acetyltransferase. (354 aa)
	AGXT2	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (506 aa)
	SPTLC3	Serine palmitoyltransferase long chain base subunit 3. (552 aa)
	PDXDC1	Pyridoxal dependent decarboxylase domain containing 1. (923 aa)
	HDC	Histidine decarboxylase. (663 aa)
	GAD1	Glutamate decarboxylase 1. (595 aa)
	CTH	Cystathionine gamma-lyase. (405 aa)
	GOT2	Aspartate aminotransferase. (408 aa)
	ABAT	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
	GADL1	Glutamate decarboxylase like 1. (470 aa)
	GAD2	Glutamate decarboxylase 2. (587 aa)
	GOT1	Aspartate aminotransferase. (465 aa)
	MOCOS	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (830 aa)
	PHYKPL	5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (516 aa)
	DDC	Dopa decarboxylase. (485 aa)
	GOT1L1	Aminotran_1_2 domain-containing protein. (451 aa)
	NFS1	Aminotran_5 domain-containing protein. (424 aa)
	SGPL1	Sphingosine-1-phosphate lyase 1. (568 aa)
	KYAT1	Aminotran_1_2 domain-containing protein. (424 aa)
	PSAT1	Phosphoserine aminotransferase. (374 aa)

Your Current Organism:

Sarcophilus harrisii

NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AADAT	ABAT	ENSSHAP00000010245	ENSSHAP00000015288	Aminoadipate aminotransferase.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.432
AADAT	AGXT2	ENSSHAP00000010245	ENSSHAP00000011581	Aminoadipate aminotransferase.	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.464
AADAT	CTH	ENSSHAP00000010245	ENSSHAP00000013466	Aminoadipate aminotransferase.	Cystathionine gamma-lyase.	0.400
AADAT	GOT1	ENSSHAP00000010245	ENSSHAP00000016451	Aminoadipate aminotransferase.	Aspartate aminotransferase.	0.524
AADAT	GOT1L1	ENSSHAP00000010245	ENSSHAP00000019868	Aminoadipate aminotransferase.	Aminotran_1_2 domain-containing protein.	0.435
AADAT	GOT2	ENSSHAP00000010245	ENSSHAP00000013576	Aminoadipate aminotransferase.	Aspartate aminotransferase.	0.589
AADAT	KYAT1	ENSSHAP00000010245	ENSSHAP00000022288	Aminoadipate aminotransferase.	Aminotran_1_2 domain-containing protein.	0.940
AADAT	KYAT3	ENSSHAP00000010245	ENSSHAP00000004193	Aminoadipate aminotransferase.	Kynurenine aminotransferase 3.	0.940
AADAT	OAT	ENSSHAP00000010245	ENSSHAP00000005291	Aminoadipate aminotransferase.	Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.416
AADAT	PHYKPL	ENSSHAP00000010245	ENSSHAP00000018656	Aminoadipate aminotransferase.	5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.432
ABAT	AADAT	ENSSHAP00000015288	ENSSHAP00000010245	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Aminoadipate aminotransferase.	0.432
ABAT	AGXT2	ENSSHAP00000015288	ENSSHAP00000011581	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.934
ABAT	CSAD	ENSSHAP00000015288	ENSSHAP00000001658	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Cysteine sulfinic acid decarboxylase.	0.482
ABAT	DDC	ENSSHAP00000015288	ENSSHAP00000019261	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Dopa decarboxylase.	0.428
ABAT	GAD1	ENSSHAP00000015288	ENSSHAP00000013413	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamate decarboxylase 1.	0.946
ABAT	GAD2	ENSSHAP00000015288	ENSSHAP00000015613	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamate decarboxylase 2.	0.946
ABAT	GADL1	ENSSHAP00000015288	ENSSHAP00000015397	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamate decarboxylase like 1.	0.482
ABAT	GOT1	ENSSHAP00000015288	ENSSHAP00000016451	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Aspartate aminotransferase.	0.475
ABAT	GOT1L1	ENSSHAP00000015288	ENSSHAP00000019868	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Aminotran_1_2 domain-containing protein.	0.513
ABAT	HDC	ENSSHAP00000015288	ENSSHAP00000013033	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Histidine decarboxylase.	0.426