STRINGSTRING
G3VA64_SARHA G3VA64_SARHA G3VB80_SARHA G3VB80_SARHA UBC UBC FGF4 FGF4 POLR2A POLR2A G3VL00_SARHA G3VL00_SARHA FGF3 FGF3 MKNK1 MKNK1 NCBP2 NCBP2 FRS2 FRS2 RPS27A RPS27A HNRNPM HNRNPM PTBP1 PTBP1 POLR2G POLR2G PTPN11 PTPN11 POLR2H POLR2H POLR2K POLR2K FGF9 FGF9 KRAS KRAS FNDC3B FNDC3B RBFOX2 RBFOX2 UBA52 UBA52 MAPK1 MAPK1 CBL CBL PIK3R1 PIK3R1 MKNK2 MKNK2 POLR2F POLR2F PPP2CB PPP2CB FGF8 FGF8 FGF23 FGF23 FGF22 FGF22 GAB1 GAB1 FGF1 FGF1 CSDE1 CSDE1 FNDC3A FNDC3A POLR2J POLR2J FGF2 FGF2 POLR2E POLR2E G3WB69_SARHA G3WB69_SARHA MAPK3 MAPK3 FGF16 FGF16 SPRY2 SPRY2 LOC100921959 LOC100921959 TIAL1 TIAL1 TIA1 TIA1 UBB UBB LOC100932920 LOC100932920 FGF20 FGF20 PTBP3 PTBP3 SOS1 SOS1 POLR2D POLR2D NCBP1 NCBP1 BRAF BRAF POLR2B POLR2B PTBP2 PTBP2 G3WUZ8_SARHA G3WUZ8_SARHA PIK3CA PIK3CA PPP2CA PPP2CA FGF7 FGF7 G3WZ44_SARHA G3WZ44_SARHA PLCG1 PLCG1 G3X039_SARHA G3X039_SARHA FGF17 FGF17 FGF5 FGF5 GRB2 GRB2 FGFBP2 FGFBP2 FGFBP1 FGFBP1 FGFBP3 FGFBP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G3VA64_SARHARRM domain-containing protein. (423 aa)
G3VB80_SARHATranscription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (513 aa)
UBCUncharacterized protein. (303 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1921 aa)
G3VL00_SARHAUncharacterized protein. (503 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (263 aa)
MKNK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (346 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (132 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
RPS27AUbiquitin-like domain-containing protein. (163 aa)
HNRNPMHeterogeneous nuclear ribonucleoprotein M. (547 aa)
PTBP1Polypyrimidine tract binding protein 1. (557 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (602 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (138 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
KRASKRAS proto-oncogene, GTPase. (198 aa)
FNDC3BFibronectin type III domain containing 3B. (1058 aa)
RBFOX2RNA binding protein fox-1 homolog 2; RNA-binding protein that regulates alternative splicing events. (400 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
MAPK1Mitogen-activated protein kinase. (348 aa)
CBLCbl proto-oncogene. (774 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
MKNK2MAPK interacting serine/threonine kinase 2. (369 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (249 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (245 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (182 aa)
GAB1GRB2 associated binding protein 1. (694 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
CSDE1Cold shock domain containing E1. (816 aa)
FNDC3AFibronectin type III domain containing 3A. (1199 aa)
POLR2JRNA polymerase II subunit J. (85 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (203 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
G3WB69_SARHATranscription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (479 aa)
MAPK3Mitogen-activated protein kinase. (375 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (115 aa)
SPRY2Sprouty RTK signaling antagonist 2. (353 aa)
LOC100921959Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (156 aa)
TIAL1TIA1 cytotoxic granule associated RNA binding protein like 1. (395 aa)
TIA1TIA1 cytotoxic granule associated RNA binding protein. (386 aa)
UBBUbiquitin B. (233 aa)
LOC100932920Uncharacterized protein. (1215 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa)
PTBP3Polypyrimidine tract binding protein 3. (579 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1325 aa)
POLR2DRPOL4c domain-containing protein. (142 aa)
NCBP1Nuclear cap binding protein subunit 1. (738 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (716 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1167 aa)
PTBP2Polypyrimidine tract binding protein 2. (463 aa)
G3WUZ8_SARHAUncharacterized protein. (526 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
PPP2CASerine/threonine-protein phosphatase. (333 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
G3WZ44_SARHAUncharacterized protein. (206 aa)
PLCG1Phosphoinositide phospholipase C. (1225 aa)
G3X039_SARHASerine/threonine-protein phosphatase. (322 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (269 aa)
GRB2Growth factor receptor bound protein 2. (191 aa)
FGFBP2Uncharacterized protein. (224 aa)
FGFBP1Uncharacterized protein. (233 aa)
FGFBP3Fibroblast growth factor binding protein 3. (252 aa)
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
Server load: low (12%) [HD]