STRINGSTRING
UBB UBB MTOR MTOR G3VNL0_SARHA G3VNL0_SARHA RPS27A RPS27A MAPKAP1 MAPKAP1 RFFL RFFL KXD1 KXD1 UBA52 UBA52 DAXX DAXX CCNG1 CCNG1 CCNA1 CCNA1 CCNA2 CCNA2 MDM4 MDM4 PDPK1 PDPK1 CDK2 CDK2 SGK1 SGK1 PPP2CB PPP2CB AKT1 AKT1 G3W744_SARHA G3W744_SARHA PRDM1 PRDM1 MDM2 MDM2 TXNDC11 TXNDC11 ATM ATM RICTOR RICTOR USP7 USP7 PPP2R1A PPP2R1A AKT3 AKT3 UBC UBC PHF20 PHF20 G3X039_SARHA G3X039_SARHA CDK1 CDK1 MLST8 MLST8 RNF34 RNF34 PPP2CA PPP2CA TP53 TP53 PPP2R1B PPP2R1B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UBBUbiquitin B. (233 aa)
MTORSerine/threonine-protein kinase mTOR. (1680 aa)
G3VNL0_SARHAUncharacterized protein. (333 aa)
RPS27AUbiquitin-like domain-containing protein. (163 aa)
MAPKAP1MAPK associated protein 1. (522 aa)
RFFLUncharacterized protein. (379 aa)
KXD1KxDL motif containing 1. (181 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
DAXXDeath domain associated protein. (754 aa)
CCNG1Cyclin G1; Belongs to the cyclin family. (298 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (469 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (363 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (491 aa)
PDPK1Protein kinase domain-containing protein. (558 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
SGK1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (431 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
G3W744_SARHAProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (349 aa)
PRDM1PR/SET domain 1. (816 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (488 aa)
TXNDC11Thioredoxin domain containing 11. (872 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3068 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1675 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1075 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (490 aa)
AKT3AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily. (402 aa)
UBCUncharacterized protein. (303 aa)
PHF20PHD finger protein 20. (1033 aa)
G3X039_SARHASerine/threonine-protein phosphatase. (322 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
MLST8MTOR associated protein, LST8 homolog. (326 aa)
RNF34Ring finger protein 34. (395 aa)
PPP2CASerine/threonine-protein phosphatase. (333 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (371 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (540 aa)
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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