STRINGSTRING
G3VA31_SARHA G3VA31_SARHA UHMK1 UHMK1 HSPB1 HSPB1 G3W744_SARHA G3W744_SARHA NOS3 NOS3 AKT1 AKT1 GNB2 GNB2 G3W3I4_SARHA G3W3I4_SARHA EGFR EGFR ESR2 ESR2 PIK3R1 PIK3R1 PDPK1 PDPK1 PRMT8 PRMT8 KRAS KRAS GNAI1 GNAI1 AREG AREG MMP9 MMP9 S1PR3 S1PR3 LOC100920799 LOC100920799 GNGT1 GNGT1 PRMT1 PRMT1 G3VKV5_SARHA G3VKV5_SARHA GNG12 GNG12 STRN STRN MMP7 MMP7 GNG13 GNG13 IGF1R IGF1R STRN3 STRN3 CREB1 CREB1 G3WQ31_SARHA G3WQ31_SARHA CAV2 CAV2 ESR1 ESR1 CAV1 CAV1 HBEGF HBEGF GNB3 GNB3 PIK3CA PIK3CA SPHK1 SPHK1 EPGN EPGN EREG EREG GNB4 GNB4 ZDHHC21 ZDHHC21 GNB5 GNB5 GNG5 GNG5 GNAI2 GNAI2 GNG8 GNG8 EGF EGF PIK3R2 PIK3R2 CSDE1 CSDE1 ZDHHC7 ZDHHC7 TGFA TGFA WDR64 WDR64 PTK2 PTK2 XPO1 XPO1 AKT3 AKT3 GNB1 GNB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G3VA31_SARHAWD_REPEATS_REGION domain-containing protein. (279 aa)
UHMK1U2AF homology motif kinase 1. (413 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (218 aa)
G3W744_SARHAProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (349 aa)
NOS3Nitric oxide synthase 3. (1022 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
GNB2G protein subunit beta 2. (340 aa)
G3W3I4_SARHAWD_REPEATS_REGION domain-containing protein. (348 aa)
EGFRReceptor protein-tyrosine kinase. (1152 aa)
ESR2Estrogen receptor 2. (559 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
PDPK1Protein kinase domain-containing protein. (558 aa)
PRMT8Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (334 aa)
KRASKRAS proto-oncogene, GTPase. (198 aa)
GNAI1G protein subunit alpha i1. (354 aa)
AREGEGF-like domain-containing protein. (243 aa)
MMP9Matrix metallopeptidase 9. (717 aa)
S1PR3Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (377 aa)
LOC100920799Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
PRMT1Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (369 aa)
G3VKV5_SARHAUncharacterized protein. (438 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
STRNStriatin. (708 aa)
MMP7ZnMc domain-containing protein. (264 aa)
GNG13G protein subunit gamma 13. (67 aa)
IGF1RTyrosine-protein kinase receptor. (1061 aa)
STRN3Striatin 3. (719 aa)
CREB1cAMP responsive element binding protein 1. (327 aa)
G3WQ31_SARHARecep_L_domain domain-containing protein. (181 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (588 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (188 aa)
HBEGFHeparin binding EGF like growth factor. (210 aa)
GNB3G protein subunit beta 3. (340 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
SPHK1Sphingosine kinase 1. (453 aa)
EPGNEpithelial mitogen. (147 aa)
EREGEpiregulin. (165 aa)
GNB4G protein subunit beta 4. (340 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (266 aa)
GNB5G protein subunit beta 5. (395 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNAI2G protein subunit alpha i2. (319 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
EGFEpidermal growth factor. (1129 aa)
PIK3R2Uncharacterized protein. (738 aa)
CSDE1Cold shock domain containing E1. (816 aa)
ZDHHC7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (308 aa)
TGFATransforming growth factor alpha. (159 aa)
WDR64WD repeat domain 64. (1029 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1052 aa)
XPO1Exportin 1. (1071 aa)
AKT3AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily. (402 aa)
GNB1G protein subunit beta 1. (340 aa)
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.